Multi-Channel-Based Differential Pathlength Factor Estimation for Continuous-Wave fNIRS

• Published in: IEEE access Vol. 9; pp. 37386 - 37396
• Main Authors: Huang, Ruisen, Hong, Keum-Shik
• Format: Journal Article
• Language: English
• Published: Piscataway IEEE 2021; The Institute of Electrical and Electronics Engineers, Inc. (IEEE)
• Subjects: Absorption; Bouguer law; Brain; Confidence; Continuous radiation; Differential pathlength factor (DPF); Emitters; Estimation; Finite element method; finite element method (FEM); functional near-infrared spectroscopy (fNIRS); Hemodynamic responses; Infrared spectra; Jacobi matrix method; Jacobian matrix; Kalman filter; Kalman filters; Luminous intensity; Mathematical model; Medical imaging; Near infrared radiation; Parameter estimation; Parameter modification; Scattering; State space models; state-space method; State-space methods; Wavelength measurement

Functional near-infrared spectroscopy (fNIRS) in brain imaging needs to be robust to subject-wise variability. The use of a fixed differential pathlength factor (DPF) per wavelength for the entire brain will degrade the accuracy of hemodynamic responses. Since the tissue composition varies within th...