Therapeutic Hypothermia May Improve Neurological Outcomes in Extracorporeal Life Support for Adult Cardiac Arrest
Background Limited data exists on patients receiving therapeutic hypothermia during extracorporeal life support (ECLS). We investigated outcomes and prognostic factors in these patients. Methods A retrospective review was conducted for 225 consecutive adult patients treated with ECLS between July 20...
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Published in | Heart, lung & circulation Vol. 26; no. 8; pp. 817 - 824 |
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Main Authors | , , , , , , , , , , , , , |
Format | Journal Article |
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Elsevier B.V
01.08.2017
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Abstract | Background Limited data exists on patients receiving therapeutic hypothermia during extracorporeal life support (ECLS). We investigated outcomes and prognostic factors in these patients. Methods A retrospective review was conducted for 225 consecutive adult patients treated with ECLS between July 2003 and January 2016. Extracorporeal life support was initiated for refractory cardiac arrest (>10 mins) in 79 patients (35.1%). Patient demographics, ECLS-related complications, in-hospital mortality and neurological outcomes were analysed. Results The mean age was 49.9 ± 12.4 years. Sixty-two patients (78.5%) were male. The mean duration of CPR and ECLS were respectively, 32.0 ± 23.3 mins and 5.4±4.0 days. Therapeutic hypothermia (34o C) was maintained for 24 hours in 14 patients (17.7%). Thirty-five patients (44.3%) were weaned off ECLS. Twenty-one patients (26.6%) survived to hospital discharge with 16 (20.3%) recovering good neurological function. Compared to ECLS at normothermia, neurologically favourable survival was higher in the hypothermia group (42.9% vs 15.4%, P =0.020). Multivariable analysis identified a non-shockable rhythm [odds ratio (OR) 5.1, confidence interval (CI) 1.5–16.8], ischaemic hepatitis (OR 6.2, CI 1.1–33.6) and hypoxic ischaemic encephalopathy (OR 5.1, CI 1.5–17.1) as predictors of in-hospital mortality. Therapeutic hypothermia (OR 4.9, CI 1.2–20.4) and acute renal failure (OR 0.19, CI 0.05–0.70) were predictors of neurologically favourable survival. Conclusions In this report of patients treated with ECLS, in-hospital survival and survival with good neurological performance were 26.6% and 20.3% respectively. A non-shockable rhythm, ischaemic hepatitis and hypoxic ischaemic encephalopathy were predictors of in-hospital mortality. Therapeutic hypothermia during ECLS was associated with improved neurological outcomes. |
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AbstractList | Background Limited data exists on patients receiving therapeutic hypothermia during extracorporeal life support (ECLS). We investigated outcomes and prognostic factors in these patients. Methods A retrospective review was conducted for 225 consecutive adult patients treated with ECLS between July 2003 and January 2016. Extracorporeal life support was initiated for refractory cardiac arrest (>10 mins) in 79 patients (35.1%). Patient demographics, ECLS-related complications, in-hospital mortality and neurological outcomes were analysed. Results The mean age was 49.9 ± 12.4 years. Sixty-two patients (78.5%) were male. The mean duration of CPR and ECLS were respectively, 32.0 ± 23.3 mins and 5.4±4.0 days. Therapeutic hypothermia (34o C) was maintained for 24 hours in 14 patients (17.7%). Thirty-five patients (44.3%) were weaned off ECLS. Twenty-one patients (26.6%) survived to hospital discharge with 16 (20.3%) recovering good neurological function. Compared to ECLS at normothermia, neurologically favourable survival was higher in the hypothermia group (42.9% vs 15.4%, P =0.020). Multivariable analysis identified a non-shockable rhythm [odds ratio (OR) 5.1, confidence interval (CI) 1.5–16.8], ischaemic hepatitis (OR 6.2, CI 1.1–33.6) and hypoxic ischaemic encephalopathy (OR 5.1, CI 1.5–17.1) as predictors of in-hospital mortality. Therapeutic hypothermia (OR 4.9, CI 1.2–20.4) and acute renal failure (OR 0.19, CI 0.05–0.70) were predictors of neurologically favourable survival. Conclusions In this report of patients treated with ECLS, in-hospital survival and survival with good neurological performance were 26.6% and 20.3% respectively. A non-shockable rhythm, ischaemic hepatitis and hypoxic ischaemic encephalopathy were predictors of in-hospital mortality. Therapeutic hypothermia during ECLS was associated with improved neurological outcomes. Limited data exists on patients receiving therapeutic hypothermia during extracorporeal life support (ECLS). We investigated outcomes and prognostic factors in these patients. A retrospective review was conducted for 225 consecutive adult patients treated with ECLS between July 2003 and January 2016. Extracorporeal life support was initiated for refractory cardiac arrest (>10 mins) in 79 patients (35.1%). Patient demographics, ECLS-related complications, in-hospital mortality and neurological outcomes were analysed. The mean age was 49.9±12.4 years. Sixty-two patients (78.5%) were male. The mean duration of CPR and ECLS were respectively, 32.0±23.3 mins and 5.4±4.0 days. Therapeutic hypothermia (34 C) was maintained for 24hours in 14 patients (17.7%). Thirty-five patients (44.3%) were weaned off ECLS. Twenty-one patients (26.6%) survived to hospital discharge with 16 (20.3%) recovering good neurological function. Compared to ECLS at normothermia, neurologically favourable survival was higher in the hypothermia group (42.9% vs 15.4%, p=0.020). Multivariable analysis identified a non-shockable rhythm [odds ratio (OR) 5.1, confidence interval (CI) 1.5-16.8], ischaemic hepatitis (OR 6.2, CI 1.1-33.6) and hypoxic ischaemic encephalopathy (OR 5.1, CI 1.5-17.1) as predictors of in-hospital mortality. Therapeutic hypothermia (OR 4.9, CI 1.2-20.4) and acute renal failure (OR 0.19, CI 0.05-0.70) were predictors of neurologically favourable survival. In this report of patients treated with ECLS, in-hospital survival and survival with good neurological performance were 26.6% and 20.3% respectively. A non-shockable rhythm, ischaemic hepatitis and hypoxic ischaemic encephalopathy were predictors of in-hospital mortality. Therapeutic hypothermia during ECLS was associated with improved neurological outcomes. Limited data exists on patients receiving therapeutic hypothermia during extracorporeal life support (ECLS). We investigated outcomes and prognostic factors in these patients. A retrospective review was conducted for 225 consecutive adult patients treated with ECLS between July 2003 and January 2016. Extracorporeal life support was initiated for refractory cardiac arrest (>10 mins) in 79 patients (35.1%). Patient demographics, ECLS-related complications, in-hospital mortality and neurological outcomes were analysed. The mean age was 49.9±12.4 years. Sixty-two patients (78.5%) were male. The mean duration of CPR and ECLS were respectively, 32.0±23.3 mins and 5.4±4.0 days. Therapeutic hypothermia (34oC) was maintained for 24hours in 14 patients (17.7%). Thirty-five patients (44.3%) were weaned off ECLS. Twenty-one patients (26.6%) survived to hospital discharge with 16 (20.3%) recovering good neurological function. Compared to ECLS at normothermia, neurologically favourable survival was higher in the hypothermia group (42.9% vs 15.4%, p=0.020). Multivariable analysis identified a non-shockable rhythm [odds ratio (OR) 5.1, confidence interval (CI) 1.5–16.8], ischaemic hepatitis (OR 6.2, CI 1.1–33.6) and hypoxic ischaemic encephalopathy (OR 5.1, CI 1.5–17.1) as predictors of in-hospital mortality. Therapeutic hypothermia (OR 4.9, CI 1.2–20.4) and acute renal failure (OR 0.19, CI 0.05–0.70) were predictors of neurologically favourable survival. In this report of patients treated with ECLS, in-hospital survival and survival with good neurological performance were 26.6% and 20.3% respectively. A non-shockable rhythm, ischaemic hepatitis and hypoxic ischaemic encephalopathy were predictors of in-hospital mortality. Therapeutic hypothermia during ECLS was associated with improved neurological outcomes. BACKGROUNDLimited data exists on patients receiving therapeutic hypothermia during extracorporeal life support (ECLS). We investigated outcomes and prognostic factors in these patients.METHODSA retrospective review was conducted for 225 consecutive adult patients treated with ECLS between July 2003 and January 2016. Extracorporeal life support was initiated for refractory cardiac arrest (>10 mins) in 79 patients (35.1%). Patient demographics, ECLS-related complications, in-hospital mortality and neurological outcomes were analysed.RESULTSThe mean age was 49.9±12.4 years. Sixty-two patients (78.5%) were male. The mean duration of CPR and ECLS were respectively, 32.0±23.3 mins and 5.4±4.0 days. Therapeutic hypothermia (34oC) was maintained for 24hours in 14 patients (17.7%). Thirty-five patients (44.3%) were weaned off ECLS. Twenty-one patients (26.6%) survived to hospital discharge with 16 (20.3%) recovering good neurological function. Compared to ECLS at normothermia, neurologically favourable survival was higher in the hypothermia group (42.9% vs 15.4%, p=0.020). Multivariable analysis identified a non-shockable rhythm [odds ratio (OR) 5.1, confidence interval (CI) 1.5-16.8], ischaemic hepatitis (OR 6.2, CI 1.1-33.6) and hypoxic ischaemic encephalopathy (OR 5.1, CI 1.5-17.1) as predictors of in-hospital mortality. Therapeutic hypothermia (OR 4.9, CI 1.2-20.4) and acute renal failure (OR 0.19, CI 0.05-0.70) were predictors of neurologically favourable survival.CONCLUSIONSIn this report of patients treated with ECLS, in-hospital survival and survival with good neurological performance were 26.6% and 20.3% respectively. A non-shockable rhythm, ischaemic hepatitis and hypoxic ischaemic encephalopathy were predictors of in-hospital mortality. Therapeutic hypothermia during ECLS was associated with improved neurological outcomes. |
Author | Sin, Yoong Kong, MD Huang, Ming Jie, MD Pang, Philip Y.K., MD Abdul Salam, Zakir Hussain, MD, MPH Tahir Sheriff, Ismail Mohamed, BSc Loh, Yee Jim, MD Kerk, Ka Lee, BSc Chao, Victor T.T., MD Hoo, Anne E.E., BSc Lim, Chong Hee, MD Tan, Teing Ee, MD Wee, Gillian H.L., MN Soon, Jia Lin, MD Lim, See Lim, MD |
Author_xml | – sequence: 1 fullname: Pang, Philip Y.K., MD – sequence: 2 fullname: Wee, Gillian H.L., MN – sequence: 3 fullname: Huang, Ming Jie, MD – sequence: 4 fullname: Hoo, Anne E.E., BSc – sequence: 5 fullname: Tahir Sheriff, Ismail Mohamed, BSc – sequence: 6 fullname: Lim, See Lim, MD – sequence: 7 fullname: Tan, Teing Ee, MD – sequence: 8 fullname: Loh, Yee Jim, MD – sequence: 9 fullname: Chao, Victor T.T., MD – sequence: 10 fullname: Soon, Jia Lin, MD – sequence: 11 fullname: Kerk, Ka Lee, BSc – sequence: 12 fullname: Abdul Salam, Zakir Hussain, MD, MPH – sequence: 13 fullname: Sin, Yoong Kong, MD – sequence: 14 fullname: Lim, Chong Hee, MD |
BackLink | https://www.ncbi.nlm.nih.gov/pubmed/28159528$$D View this record in MEDLINE/PubMed |
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Cites_doi | 10.1016/j.athoracsur.2004.06.095 10.1016/j.jtcvs.2015.05.070 10.1186/s13019-016-0437-8 10.1056/NEJM198602133140701 10.1253/circj.CJ-09-0502 10.1016/j.resuscitation.2014.09.026 10.1016/j.resuscitation.2015.04.016 10.1016/S0300-9572(03)00215-6 10.1016/S0140-6736(08)60958-7 10.1016/j.athoracsur.2012.01.032 10.1097/CCM.0b013e31827ca4c8 10.1016/j.resuscitation.2014.09.010 10.1016/j.ijcard.2015.11.165 10.1016/j.resuscitation.2012.07.009 10.1016/j.athoracsur.2013.09.008 10.1016/j.resuscitation.2011.10.013 10.1016/j.ijcard.2013.04.183 10.1016/j.jtcvs.2015.07.061 10.1056/NEJMoa1310519 10.1016/j.resuscitation.2010.03.037 10.1016/j.resuscitation.2014.06.022 10.1056/NEJMoa003289 |
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Copyright | Australian and New Zealand Society of Cardiac and Thoracic Surgeons (ANZSCTS) and the Cardiac Society of Australia and New Zealand (CSANZ) 2017 Australian and New Zealand Society of Cardiac and Thoracic Surgeons (ANZSCTS) and the Cardiac Society of Australia and New Zealand (CSANZ) Copyright © 2017 Australian and New Zealand Society of Cardiac and Thoracic Surgeons (ANZSCTS) and the Cardiac Society of Australia and New Zealand (CSANZ). Published by Elsevier B.V. All rights reserved. |
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Keywords | Therapeutic hypothermia Cardiac arrest Extracorporeal life support |
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References | Shin, Jo, Sim, Song, Yang, Hahn (bib0185) 2013; 168 Wang, Chou, Becker, Lin, Yu, Chi (bib0145) 2014; 85 Nielsen, Wetterslev, Cronberg, Erlinge, Gasche, Hassager (bib0210) 2013; 369 Nagao, Kikushima, Watanabe, Tachibana, Tominaga, Tada (bib0220) 2010; 74 Cheng, Hachamovitch, Kittleson, Patel, Arabia, Moriguchi (bib0225) 2014; 97 Massetti, Tasle, Le Page, Deredec, Babatasi, Buklas (bib0165) 2005; 79 Anselmi, Flécher, Corbineau, Langanay, Le Bouquin, Bedossa (bib0195) 2015; 150 Peberdy, Kaye, Ornato, Larkin, Nadkarni, Mancini (bib0120) 2003; 58 Avalli, Maggioni, Formica, Redaelli, Migliari, Scanziani (bib0155) 2012; 83 Cronberg, Lilja, Horn, Kjaergaard, Wise, Pellis (bib0215) 2015; 72 Sakamoto, Taniguchi, Nakajima, Takahashi (bib0130) 2012; 94 Pozzi, Koffel, Armoiry, Pavlakovic, Neidecker, Prieur (bib0170) 2016; 204 Peigh, Cavarocchi, Hirose (bib0190) 2015; 150 Pang, Wee, Hoo, Sheriff, Lim, Tan (bib0230) 2016; 11 Stub, Bernard, Pellegrino, Smith, Walker, Sheldrake (bib0200) 2015; 86 Maekawa, Tanno, Hase, Mori, Asai (bib0180) 2013; 41 Haneya, Philipp, Diez, Schopka, Bein, Zimmermann (bib0160) 2012; 83 Bednarczyk, White, Ducas, Golian, Nepomuceno, Hiebert (bib0135) 2014; 85 Siao, Chiu, Chiu, Chen, Chen, Hsieh (bib0140) 2015; 92 Kagawa, Inoue, Kawagoe, Ishihara, Shimatani, Kurisu (bib0150) 2010; 81 Chen, Lin, Yu, Ko, Jerng, Chang (bib0125) 2008; 372 (bib0175) 1986; 314 Bernard, Gray, Buist, Jones, Silvester, Gutteridge (bib0205) 2002; 346 (10.1016/j.hlc.2016.11.022_bib0175) 1986; 314 Anselmi (10.1016/j.hlc.2016.11.022_bib0195) 2015; 150 Bednarczyk (10.1016/j.hlc.2016.11.022_bib0135) 2014; 85 Maekawa (10.1016/j.hlc.2016.11.022_bib0180) 2013; 41 Peigh (10.1016/j.hlc.2016.11.022_bib0190) 2015; 150 Cronberg (10.1016/j.hlc.2016.11.022_bib0215) 2015; 72 Cheng (10.1016/j.hlc.2016.11.022_bib0225) 2014; 97 Nielsen (10.1016/j.hlc.2016.11.022_bib0210) 2013; 369 Pozzi (10.1016/j.hlc.2016.11.022_bib0170) 2016; 204 Shin (10.1016/j.hlc.2016.11.022_bib0185) 2013; 168 Wang (10.1016/j.hlc.2016.11.022_bib0145) 2014; 85 Kagawa (10.1016/j.hlc.2016.11.022_bib0150) 2010; 81 Bernard (10.1016/j.hlc.2016.11.022_bib0205) 2002; 346 Peberdy (10.1016/j.hlc.2016.11.022_bib0120) 2003; 58 Sakamoto (10.1016/j.hlc.2016.11.022_bib0130) 2012; 94 Haneya (10.1016/j.hlc.2016.11.022_bib0160) 2012; 83 Massetti (10.1016/j.hlc.2016.11.022_bib0165) 2005; 79 Nagao (10.1016/j.hlc.2016.11.022_bib0220) 2010; 74 Chen (10.1016/j.hlc.2016.11.022_bib0125) 2008; 372 Siao (10.1016/j.hlc.2016.11.022_bib0140) 2015; 92 Pang (10.1016/j.hlc.2016.11.022_bib0230) 2016; 11 Stub (10.1016/j.hlc.2016.11.022_bib0200) 2015; 86 Avalli (10.1016/j.hlc.2016.11.022_bib0155) 2012; 83 |
References_xml | – volume: 58 start-page: 297 year: 2003 end-page: 308 ident: bib0120 article-title: Cardiopulmonary resuscitation of adults in the hospital: a report of 14720 cardiac arrests from the National Registry of Cardiopulmonary Resuscitation publication-title: Resuscitation. contributor: fullname: Mancini – volume: 346 start-page: 557 year: 2002 end-page: 563 ident: bib0205 article-title: Treatment of comatose survivors of out-of-hospital cardiac arrest with induced hypothermia publication-title: N Engl J Med. contributor: fullname: Gutteridge – volume: 369 start-page: 2197 year: 2013 end-page: 2206 ident: bib0210 article-title: Targeted temperature management at 33 publication-title: N Engl J Med. contributor: fullname: Hassager – volume: 168 start-page: 3424 year: 2013 end-page: 3430 ident: bib0185 article-title: Two-year survival and neurological outcome of in-hospital cardiac arrest patients rescued by extracorporeal cardiopulmonary resuscitation publication-title: Int J Cardiol. contributor: fullname: Hahn – volume: 314 start-page: 397 year: 1986 end-page: 403 ident: bib0175 article-title: Randomized clinical study of thiopental loading in comatose survivors of cardiac arrest publication-title: N Engl J Med – volume: 83 start-page: 1331 year: 2012 end-page: 1337 ident: bib0160 article-title: A 5-year experience with cardiopulmonary resuscitation using extracorporeal life support in non-postcardiotomy patients with cardiac arrest publication-title: Resuscitation. contributor: fullname: Zimmermann – volume: 41 start-page: 1186 year: 2013 end-page: 1196 ident: bib0180 article-title: Extracorporeal cardiopulmonary resuscitation for patients with out-of-hospital cardiac arrest of cardiac origin: a propensity-matched study and predictor analysis publication-title: Crit Care Med. contributor: fullname: Asai – volume: 204 start-page: 70 year: 2016 end-page: 76 ident: bib0170 article-title: Extracorporeal life support for refractory out-of-hospital cardiac arrest: Should we still fight for?. A single-centre, 5-year experience publication-title: Int J Cardiol. contributor: fullname: Prieur – volume: 11 start-page: 43 year: 2016 ident: bib0230 article-title: Therapeutic hypothermia in adult patients receiving extracorporeal life support: early results of a randomized controlled study publication-title: J Cardiothorac Surg. contributor: fullname: Tan – volume: 372 start-page: 554 year: 2008 end-page: 561 ident: bib0125 article-title: Cardiopulmonary resuscitation with assisted extracorporeal life-support versus conventional cardiopulmonary resuscitation in adults with in-hospital cardiac arrest: an observational study and propensity analysis publication-title: Lancet. contributor: fullname: Chang – volume: 92 start-page: 70 year: 2015 end-page: 76 ident: bib0140 article-title: Managing cardiac arrest with refractory ventricular fibrillation in the emergency department: Conventional cardiopulmonary resuscitation versus extracorporeal cardiopulmonary resuscitation publication-title: Resuscitation. contributor: fullname: Hsieh – volume: 74 start-page: 77 year: 2010 end-page: 85 ident: bib0220 article-title: Early induction of hypothermia during cardiac arrest improves neurological outcomes in patients with out-of-hospital cardiac arrest who undergo emergency cardiopulmonary bypass and percutaneous coronary intervention publication-title: Circ J. contributor: fullname: Tada – volume: 79 start-page: 178 year: 2005 end-page: 183 ident: bib0165 article-title: Back from irreversibility: extracorporeal life support for prolonged cardiac arrest publication-title: Ann Thorac Surg. contributor: fullname: Buklas – volume: 85 start-page: 1219 year: 2014 end-page: 1224 ident: bib0145 article-title: Improved outcome of extracorporeal cardiopulmonary resuscitation for out-of-hospital cardiac arrest--a comparison with that for extracorporeal rescue for in-hospital cardiac arrest publication-title: Resuscitation. contributor: fullname: Chi – volume: 83 start-page: 579 year: 2012 end-page: 583 ident: bib0155 article-title: Favourable survival of in-hospital compared to out-of-hospital refractory cardiac arrest patients treated with extracorporeal membrane oxygenation: an Italian tertiary care centre experience publication-title: Resuscitation. contributor: fullname: Scanziani – volume: 81 start-page: 968 year: 2010 end-page: 973 ident: bib0150 article-title: Assessment of outcomes and differences between in- and out-of-hospital cardiac arrest patients treated with cardiopulmonary resuscitation using extracorporeal life support publication-title: Resuscitation. contributor: fullname: Kurisu – volume: 97 start-page: 610 year: 2014 end-page: 616 ident: bib0225 article-title: Complications of extracorporeal membrane oxygenation for treatment of cardiogenic shock and cardiac arrest: a meta-analysis of 1,866 adult patients publication-title: Ann Thorac Surg. contributor: fullname: Moriguchi – volume: 94 start-page: 1 year: 2012 end-page: 7 ident: bib0130 article-title: Extracorporeal life support for cardiogenic shock or cardiac arrest due to acute coronary syndrome publication-title: Ann Thorac Surg. contributor: fullname: Takahashi – volume: 85 start-page: 1713 year: 2014 end-page: 1719 ident: bib0135 article-title: Resuscitative extracorporeal membrane oxygenation for in hospital cardiac arrest: a Canadian observational experience publication-title: Resuscitation. contributor: fullname: Hiebert – volume: 150 start-page: 947 year: 2015 end-page: 954 ident: bib0195 article-title: Survival and quality of life after extracorporeal life support for refractory cardiac arrest: A case series publication-title: J Thorac Cardiovasc Surg. contributor: fullname: Bedossa – volume: 150 start-page: 1344 year: 2015 end-page: 1349 ident: bib0190 article-title: Saving life and brain with extracorporeal cardiopulmonary resuscitation: A single-center analysis of in-hospital cardiac arrests publication-title: J Thorac Cardiovasc Surg. contributor: fullname: Hirose – volume: 86 start-page: 88 year: 2015 end-page: 94 ident: bib0200 article-title: Refractory cardiac arrest treated with mechanical CPR, hypothermia, ECMO and early reperfusion (the CHEER trial) publication-title: Resuscitation. contributor: fullname: Sheldrake – volume: 72 start-page: 634 year: 2015 end-page: 641 ident: bib0215 article-title: Neurologic Function and Health-Related Quality of Life in Patients Following Targeted Temperature Management at 33 contributor: fullname: Pellis – volume: 79 start-page: 178 year: 2005 ident: 10.1016/j.hlc.2016.11.022_bib0165 article-title: Back from irreversibility: extracorporeal life support for prolonged cardiac arrest publication-title: Ann Thorac Surg. doi: 10.1016/j.athoracsur.2004.06.095 contributor: fullname: Massetti – volume: 150 start-page: 947 year: 2015 ident: 10.1016/j.hlc.2016.11.022_bib0195 article-title: Survival and quality of life after extracorporeal life support for refractory cardiac arrest: A case series publication-title: J Thorac Cardiovasc Surg. doi: 10.1016/j.jtcvs.2015.05.070 contributor: fullname: Anselmi – volume: 11 start-page: 43 year: 2016 ident: 10.1016/j.hlc.2016.11.022_bib0230 article-title: Therapeutic hypothermia in adult patients receiving extracorporeal life support: early results of a randomized controlled study publication-title: J Cardiothorac Surg. doi: 10.1186/s13019-016-0437-8 contributor: fullname: Pang – volume: 314 start-page: 397 year: 1986 ident: 10.1016/j.hlc.2016.11.022_bib0175 article-title: Randomized clinical study of thiopental loading in comatose survivors of cardiac arrest publication-title: N Engl J Med doi: 10.1056/NEJM198602133140701 – volume: 74 start-page: 77 year: 2010 ident: 10.1016/j.hlc.2016.11.022_bib0220 article-title: Early induction of hypothermia during cardiac arrest improves neurological outcomes in patients with out-of-hospital cardiac arrest who undergo emergency cardiopulmonary bypass and percutaneous coronary intervention publication-title: Circ J. doi: 10.1253/circj.CJ-09-0502 contributor: fullname: Nagao – volume: 85 start-page: 1713 year: 2014 ident: 10.1016/j.hlc.2016.11.022_bib0135 article-title: Resuscitative extracorporeal membrane oxygenation for in hospital cardiac arrest: a Canadian observational experience publication-title: Resuscitation. doi: 10.1016/j.resuscitation.2014.09.026 contributor: fullname: Bednarczyk – volume: 92 start-page: 70 year: 2015 ident: 10.1016/j.hlc.2016.11.022_bib0140 article-title: Managing cardiac arrest with refractory ventricular fibrillation in the emergency department: Conventional cardiopulmonary resuscitation versus extracorporeal cardiopulmonary resuscitation publication-title: Resuscitation. doi: 10.1016/j.resuscitation.2015.04.016 contributor: fullname: Siao – volume: 58 start-page: 297 year: 2003 ident: 10.1016/j.hlc.2016.11.022_bib0120 article-title: Cardiopulmonary resuscitation of adults in the hospital: a report of 14720 cardiac arrests from the National Registry of Cardiopulmonary Resuscitation publication-title: Resuscitation. doi: 10.1016/S0300-9572(03)00215-6 contributor: fullname: Peberdy – volume: 372 start-page: 554 year: 2008 ident: 10.1016/j.hlc.2016.11.022_bib0125 article-title: Cardiopulmonary resuscitation with assisted extracorporeal life-support versus conventional cardiopulmonary resuscitation in adults with in-hospital cardiac arrest: an observational study and propensity analysis publication-title: Lancet. doi: 10.1016/S0140-6736(08)60958-7 contributor: fullname: Chen – volume: 94 start-page: 1 year: 2012 ident: 10.1016/j.hlc.2016.11.022_bib0130 article-title: Extracorporeal life support for cardiogenic shock or cardiac arrest due to acute coronary syndrome publication-title: Ann Thorac Surg. doi: 10.1016/j.athoracsur.2012.01.032 contributor: fullname: Sakamoto – volume: 41 start-page: 1186 year: 2013 ident: 10.1016/j.hlc.2016.11.022_bib0180 article-title: Extracorporeal cardiopulmonary resuscitation for patients with out-of-hospital cardiac arrest of cardiac origin: a propensity-matched study and predictor analysis publication-title: Crit Care Med. doi: 10.1097/CCM.0b013e31827ca4c8 contributor: fullname: Maekawa – volume: 72 start-page: 634 year: 2015 ident: 10.1016/j.hlc.2016.11.022_bib0215 article-title: Neurologic Function and Health-Related Quality of Life in Patients Following Targeted Temperature Management at 33°C vs 36°C After Out-of-Hospital Cardiac Arrest: A Randomized Clinical Trial. JAMA Neurol contributor: fullname: Cronberg – volume: 86 start-page: 88 year: 2015 ident: 10.1016/j.hlc.2016.11.022_bib0200 article-title: Refractory cardiac arrest treated with mechanical CPR, hypothermia, ECMO and early reperfusion (the CHEER trial) publication-title: Resuscitation. doi: 10.1016/j.resuscitation.2014.09.010 contributor: fullname: Stub – volume: 204 start-page: 70 year: 2016 ident: 10.1016/j.hlc.2016.11.022_bib0170 article-title: Extracorporeal life support for refractory out-of-hospital cardiac arrest: Should we still fight for?. A single-centre, 5-year experience publication-title: Int J Cardiol. doi: 10.1016/j.ijcard.2015.11.165 contributor: fullname: Pozzi – volume: 83 start-page: 1331 year: 2012 ident: 10.1016/j.hlc.2016.11.022_bib0160 article-title: A 5-year experience with cardiopulmonary resuscitation using extracorporeal life support in non-postcardiotomy patients with cardiac arrest publication-title: Resuscitation. doi: 10.1016/j.resuscitation.2012.07.009 contributor: fullname: Haneya – volume: 97 start-page: 610 year: 2014 ident: 10.1016/j.hlc.2016.11.022_bib0225 article-title: Complications of extracorporeal membrane oxygenation for treatment of cardiogenic shock and cardiac arrest: a meta-analysis of 1,866 adult patients publication-title: Ann Thorac Surg. doi: 10.1016/j.athoracsur.2013.09.008 contributor: fullname: Cheng – volume: 83 start-page: 579 year: 2012 ident: 10.1016/j.hlc.2016.11.022_bib0155 article-title: Favourable survival of in-hospital compared to out-of-hospital refractory cardiac arrest patients treated with extracorporeal membrane oxygenation: an Italian tertiary care centre experience publication-title: Resuscitation. doi: 10.1016/j.resuscitation.2011.10.013 contributor: fullname: Avalli – volume: 168 start-page: 3424 year: 2013 ident: 10.1016/j.hlc.2016.11.022_bib0185 article-title: Two-year survival and neurological outcome of in-hospital cardiac arrest patients rescued by extracorporeal cardiopulmonary resuscitation publication-title: Int J Cardiol. doi: 10.1016/j.ijcard.2013.04.183 contributor: fullname: Shin – volume: 150 start-page: 1344 year: 2015 ident: 10.1016/j.hlc.2016.11.022_bib0190 article-title: Saving life and brain with extracorporeal cardiopulmonary resuscitation: A single-center analysis of in-hospital cardiac arrests publication-title: J Thorac Cardiovasc Surg. doi: 10.1016/j.jtcvs.2015.07.061 contributor: fullname: Peigh – volume: 369 start-page: 2197 year: 2013 ident: 10.1016/j.hlc.2016.11.022_bib0210 article-title: Targeted temperature management at 33°C versus 36°C after cardiac arrest publication-title: N Engl J Med. doi: 10.1056/NEJMoa1310519 contributor: fullname: Nielsen – volume: 81 start-page: 968 year: 2010 ident: 10.1016/j.hlc.2016.11.022_bib0150 article-title: Assessment of outcomes and differences between in- and out-of-hospital cardiac arrest patients treated with cardiopulmonary resuscitation using extracorporeal life support publication-title: Resuscitation. doi: 10.1016/j.resuscitation.2010.03.037 contributor: fullname: Kagawa – volume: 85 start-page: 1219 year: 2014 ident: 10.1016/j.hlc.2016.11.022_bib0145 article-title: Improved outcome of extracorporeal cardiopulmonary resuscitation for out-of-hospital cardiac arrest--a comparison with that for extracorporeal rescue for in-hospital cardiac arrest publication-title: Resuscitation. doi: 10.1016/j.resuscitation.2014.06.022 contributor: fullname: Wang – volume: 346 start-page: 557 year: 2002 ident: 10.1016/j.hlc.2016.11.022_bib0205 article-title: Treatment of comatose survivors of out-of-hospital cardiac arrest with induced hypothermia publication-title: N Engl J Med. doi: 10.1056/NEJMoa003289 contributor: fullname: Bernard |
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Snippet | Background Limited data exists on patients receiving therapeutic hypothermia during extracorporeal life support (ECLS). We investigated outcomes and prognostic... Limited data exists on patients receiving therapeutic hypothermia during extracorporeal life support (ECLS). We investigated outcomes and prognostic factors in... BACKGROUNDLimited data exists on patients receiving therapeutic hypothermia during extracorporeal life support (ECLS). We investigated outcomes and prognostic... |
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SubjectTerms | Adult Cardiac arrest Cardiovascular Disease-Free Survival Extracorporeal Circulation - adverse effects Extracorporeal Circulation - methods Extracorporeal life support Female Heart Arrest, Induced - adverse effects Heart Arrest, Induced - methods Hospital Mortality Humans Hypothermia, Induced - adverse effects Hypothermia, Induced - methods Male Middle Aged Nervous System Diseases - etiology Nervous System Diseases - mortality Postoperative Complications - mortality Retrospective Studies Survival Rate Therapeutic hypothermia |
Title | Therapeutic Hypothermia May Improve Neurological Outcomes in Extracorporeal Life Support for Adult Cardiac Arrest |
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