NPC1L1 rs217434 A > G as a Novel Single Nucleotide Polymorphism Related to Dyslipidemia in a Korean Population

• Published in: Biochemical genetics Vol. 62; no. 5; pp. 4103 - 4119
• Main Authors: Cho, Dahyun, Huang, Ximei, Han, Youngmin, Kim, Minjoo
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.10.2024; Springer Nature B.V
• Subjects: Adult; Aged; Aged, 80 and over; Asian People - genetics; Biochemistry; Biomedical and Life Sciences; Biomedicine; Blood pressure; C-reactive protein; Cholesterol; Cross-Sectional Studies; diastolic blood pressure; Dyslipidemia; Dyslipidemias - genetics; Female; Gene polymorphism; Genetic Predisposition to Disease; Genotype; Genotype & phenotype; Glucose; Human Genetics; Humans; hyperlipidemia; inflammation; lipid composition; Lipids; low density lipoprotein cholesterol; Male; Medical Microbiology; Membrane Proteins - genetics; Membrane Transport Proteins - genetics; Metabolic disorders; Middle Aged; Niemann-Pick disease; Nucleotides; Original Article; Oxidative stress; Parameter sensitivity; Polymorphism; Polymorphism, Single Nucleotide; Population studies; Prostaglandin F2a; Republic of Korea; Single-nucleotide polymorphism; Young Adult; Zoology; Republic of Korea; NPC1L1; Cholesterol; Dyslipidemia; Polymorphism

A relationship between cholesterol levels and Niemann-Pick C1-Like 1 ( NPC1L1 ) polymorphisms in diverse populations was found in previous studies. However, relevant research on this association in the Korean population is relatively scarce. Therefore, the current study sought to examine the correla...