Propolis: a natural compound with potential as an adjuvant in cancer therapy - a review of signaling pathways

• Published in: Molecular biology reports Vol. 51; no. 1; p. 931
• Main Authors: Valivand, Nassim, Aravand, Sara, Lotfi, Hajie, Esfahani, Azam Janati, Ahmadpour-Yazdi, Hossein, Gheibi, Nematollah
• Format: Journal Article
• Language: English
• Published: Dordrecht Springer Netherlands 01.12.2024; Springer Nature B.V
• Subjects: 1-Phosphatidylinositol 3-kinase; adjuvants; Adverse events; AKT protein; Angiogenesis; Animal Anatomy; Animal Biochemistry; Animals; Antifungal agents; Antineoplastic Agents - pharmacology; Antineoplastic Agents - therapeutic use; antioxidants; Antiviral agents; Antiviral drugs; Apoptosis; Bioactive compounds; Biological activity; Biological Products - pharmacology; Biological Products - therapeutic use; Biomedical and Life Sciences; Caffeic acid; Caffeic Acids - chemistry; Caffeic Acids - pharmacology; Caffeic Acids - therapeutic use; Cancer therapies; cancer therapy; Cell cycle; cell cycle checkpoints; Cell therapy; chemical composition; Chemotherapy; chrysin; Cyclin D; cyclins; drug therapy; Extracellular signal-regulated kinase; Flavonoids - pharmacology; Flavonoids - therapeutic use; Genistein; Histology; Humans; Life Sciences; MAP kinase; Metastases; metastasis; Morphology; Natural products; Neoplasms - drug therapy; Original Article; Oxidants; p-Coumaric acid; Phenylethyl Alcohol - analogs & derivatives; Phenylpropionates; propolis; Propolis - chemistry; Propolis - pharmacology; Propolis - therapeutic use; Quercetin; Radiation therapy; radiotherapy; Signal transduction; Signal Transduction - drug effects; stem cells; Up-regulation; Natural product; Chemotherapy; Radiotherapy; Propolis; Molecular mechanism; Cancer

Propolis is a natural product used in cancer treatment, which is produced by bees via different sources. The chemical composition of Propolis is determined based on the climatic and geographical conditions, as well as harvesting time and method. This compound has been the subject of numerous investi...