Advances in Research on the Toxicological Effects of Selenium

Selenium is a trace element necessary for the growth of organisms. Moreover, selenium supplementation can improve the immunity and fertility of the body, as well as its ability to resist oxidation, tumors, heavy metals, and pathogenic microorganisms. However, owing to the duality of selenium, excess...

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Bibliographic Details
Published inBulletin of environmental contamination and toxicology Vol. 106; no. 5; pp. 715 - 726
Main Authors Lv, Qizhuang, Liang, Xiaomei, Nong, Keyi, Gong, Zifeng, Qin, Ting, Qin, Xinyun, Wang, Daobo, Zhu, Yulin
Format Journal Article
LanguageEnglish
Published New York Springer US 01.05.2021
Springer Nature B.V
Subjects
Aquatic Pollution
death
Dietary Supplements
Drug development
Earth and Environmental Science
Ecotoxicology
Enriched foods
Environment
Environmental Chemistry
Environmental Health
Fertility
Focused Review
growth and development
Heavy metals
immunity
Metals, Heavy
Micronutrients
Microorganisms
Oxidation
Pharmaceutical Preparations
Pollution
R&D
Research & development
Selenium
Selenium - toxicity
Soil Science & Conservation
Toxicity
Toxicology
Trace Elements
Trace elements (nutrients)
Tumors
Waste Water Technology
Water Management
Water Pollution Control
Selenium (Se)
Toxicological effects
Mechanism
Functional agriculture
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Summary:Selenium is a trace element necessary for the growth of organisms. Moreover, selenium supplementation can improve the immunity and fertility of the body, as well as its ability to resist oxidation, tumors, heavy metals, and pathogenic microorganisms. However, owing to the duality of selenium, excessive selenium supplementation can cause certain toxic effects on the growth and development of the body and may even result in death in severe cases. At present, increasing attention is being paid to the development and utilization of selenium as a micronutrient, but its potential toxicity tends to be neglected. This study systematically reviews recent research on the toxicological effects of selenium, aiming to provide theoretical references for selenium toxicology-related research and theoretical support for the development of selenium-containing drugs, selenium-enriched dietary supplements, and selenium-enriched foods.
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ISSN:0007-4861
1432-0800
1432-0800
DOI:10.1007/s00128-020-03094-3