Vertebral morphometry : Repeat scan precision using the Lunar expert-XL and the hologic 4500A. A Study for the 'WISDOM' RCT of hormone replacement therapy

• Published in: Osteoporosis international Vol. 11; no. 6; pp. 537 - 543
• Main Authors: CRABTREE, N, WRIGHT, J, REEVE, J, WALGROVE, A, REA, J, HANRATTY, L, LUNT, M, FOGELMAN, I, PALMER, R, VICKERS, M, COMPSTON, J. E
• Format: Journal Article
• Language: English
• Published: London Springer 01.07.2000; Springer Nature B.V
• Subjects: Absorptiometry, Photon - methods; Absorptiometry, Photon - standards; Aged; Biological and medical sciences; Body mass index; Bone Density; Clinical trials; Drug dosages; Estrogen Replacement Therapy; Feasibility Studies; Female; Fractures; Health care; Hormone replacement therapy; Humans; Investigative techniques, diagnostic techniques (general aspects); Lumbar Vertebrae - diagnostic imaging; Lumbar Vertebrae - physiopathology; Medical sciences; Middle Aged; Osteoarticular system. Muscles; Osteoporosis; Osteoporosis, Postmenopausal - prevention & control; Pilot Projects; Preventive medicine; Radiation; Radiodiagnosis. Nmr imagery. Nmr spectrometry; Randomized Controlled Trials as Topic; Reproducibility; Reproducibility of Results; Software; Spine - diagnostic imaging; Spine - physiopathology; Thoracic Vertebrae - diagnostic imaging; Thoracic Vertebrae - physiopathology; Treatment Outcome; Women; United Kingdom > UK; United States > US; Human; Evaluation; Replacement therapy; Healthy subject; Treatment efficiency; Diseases of the osteoarticular system; Estrogen; Vertebra; Bone disease; Ovarian hormone; Prevention; Osteoporosis; X ray absorption spectrometry; Postmenopause; Adult; Clinical trial; Female; Sex steroid hormone; Morphometry

On radiation safety grounds there is concern about the morbidity attributable to routine radiographs of the spine for the identification of new fractures in large-scale trials of fracture prevention. However, the role of the potentially safer low-radiation-dose technique of vertebral morphometry per...