Association Between Circulating Zinc Levels and Risk Factors of Metabolic Syndrome: Insights from a Bi-directional Mendelian Randomization Analysis and Cross-Sectional Study

• Published in: Biological trace element research Vol. 202; no. 7; pp. 3051 - 3061
• Main Authors: Wu, Yuanyuan, Xu, Guoqiong, Bai, Ruixue, Yu, Pingping, He, Zhongxiang, Chen, Mengxue, Hu, Yukun, Jiang, Tao, Yang, Yuanhang, Liu, Dongfang, Mei, Ying, Qi, Xiaoya, Cheng, Feifei
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.07.2024; Springer Nature B.V
• Subjects: Adult; Biochemistry; Biomedical and Life Sciences; Biotechnology; blood; Blood levels; Cross-Sectional Studies; Female; Humans; Life Sciences; Low density lipoprotein; Male; Mendelian Randomization Analysis; Metabolic disorders; Metabolic syndrome; Metabolic Syndrome - blood; Metabolic Syndrome - genetics; Middle Aged; Nutrition; Oncology; Randomization; Retrospective Studies; risk; Risk Factors; Trace elements; Zinc; Zinc - blood; Obesity; Lipids; Mendelian randomization; Metabolic syndrome; Zinc

Previous studies on the relationship between zinc and metabolic syndrome (MetS) have yielded inconsistent results. This comprehensive study aimed to elaborately explore the impact of zinc on MetS risk factors. The bi-directional Mendelian randomization (MR) analyses were performed to estimate the ca...