Urologic Complications in 1523 Renal Transplantations: The Baskent University Experience

• Published in: Transplantation proceedings Vol. 38; no. 2; pp. 543 - 547
• Main Authors: Dalgic, A., Boyvat, F., Karakayali, H., Moray, G., Emiroglu, R., Haberal, M.
• Format: Journal Article Conference Proceeding
• Language: English
• Published: New York, NY Elsevier Inc 01.03.2006; Elsevier Science
• Subjects: Adolescent; Adult; Biological and medical sciences; Child; Female; Fundamental and applied biological sciences. Psychology; Fundamental immunology; Graft Survival; Humans; Immunosuppression - methods; Incidence; Kidney Transplantation - adverse effects; Kidney Transplantation - immunology; Kidney Transplantation - methods; Living Donors; Male; Medical sciences; Middle Aged; Retrospective Studies; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases; Surgery of the urinary system; Tissue, organ and graft immunology; Ureteral Diseases - epidemiology; Urologic Diseases - classification; Urologic Diseases - epidemiology; Urologic Diseases - etiology; Medicine; Experience; Urinary system disease; Treatment; Urinary system; University; Surgery; Complication; Graft; Homotransplantation; Kidney; Kidney transplantation
• DOI: 10.1016/j.transproceed.2005.12.116
• ISSN: 0041-1345

Urologic complications, observed since the beginning of renal transplantation, cause significant morbidity and mortality. In the first few years the procedure was performed, incidence of urologic complications was reported to be 10% to 25%. Recently, the incidence of urologic complications after renal transplantation has decreased to 2.5% to 12.5%; unfortunately, a higher incidence exists in pediatric recipients, reaching approximately 20% with an associated 58% and 74% graft survival rates for cadaveric and living-related transplantation, respectively. We retrospectively analyzed the postoperative urologic complications reported in the medical charts of 1523 consecutive kidney transplantations (1130 men, 74.2%; 393 women, 25.8%; mean age, 31.9 ± 10.9 years; range, 7 to 64 years; 354 cadaveric, 23.2%; 1169 living, 76.8%) performed by our team since 1975. The first 321 procedures took place at Hacettepe University Hospital in Ankara, Turkey, and the remaining 1202 were performed at Baskent University Hospital in Ankara. Urologic complications occurred in 46 (3%) recipients. Twenty-three (1.5%) of these patients had urine leakage, 15 (1%) had urinary obstruction due to ureteral stricture, 6 (0.4%) had distal ureter necrosis, and 2 (0.1%) developed renal calculi in the late postoperative period. Twenty-four out of 46 required reoperation for urologic complications. The remaining 22 patients were treated conservatively in our interventional radiology department with excellent results. In conclusion, urologic complications will always occur in the posttransplant period. Early diagnosis by experienced personnel and use of interventional radiology can greatly reduce the need for surgical treatment.