The effectiveness of desensitization versus rechallenge treatment in HIV-positive patients with previous hypersensitivity to TMP-SMX: a randomized multicentric study

• Published in: Biomedicine & pharmacotherapy Vol. 54; no. 1; pp. 45 - 49
• Main Authors: Bonfanti, P., Pusterla, L., Parazzini, F., Libanore, M., Cagni, A.E., Franzetti, M., Faggion, I., Landonio, S., Quirino, T.
• Format: Journal Article
• Language: English
• Published: Elsevier SAS 2000
• Subjects: desensitization; HIV infection; trimethoprim-sulphamethoxazole; HIV infection; desensitization; trimethoprim-sulphamethoxazole

Our study was undertaken to evaluate if desensitization treatment is more effective than rechallenge in preventing hypersensitivity reactions in HIV-positive patients with previous allergic reactions to TMP-SMX; the secondary aim was to evaluate the frequency of reactions to TMP alone. This was a ra...