Analysis of MUC6 polymorphisms on the clinicopathologic characteristics of Asian patients with oral squamous cell carcinoma

• Published in: Journal of cellular and molecular medicine Vol. 27; no. 17; pp. 2594 - 2602
• Main Authors: Hua, Chun‐Hung, Chuang, Chun‐Yi, Chien, Yi‐Chung, Su, Chun‐Wen, Chen, Shuo‐Chueh, Liu, Liang‐Chih, Yang, Shun‐Fa, Yu, Yung‐Luen
• Format: Journal Article
• Language: English
• Published: England John Wiley & Sons, Inc 01.09.2023; John Wiley and Sons Inc
• Subjects: Alcohol; Alcohol abuse; Carcinogens; Drug abuse; Genetic diversity; Glycoproteins; Head & neck cancer; Head and neck carcinoma; Liver cancer; lymph node metastasis; Lymph nodes; Medical prognosis; Metastases; Metastasis; MUC6; Mucin; Oral cancer; Oral carcinoma; Oral squamous cell carcinoma; Original; Phenotypes; Regression analysis; Single-nucleotide polymorphism; single‐nucleotide polymorphisms; Smoking; Software; Squamous cell carcinoma; Taiwan; oral squamous cell carcinoma; single-nucleotide polymorphisms; MUC6; lymph node metastasis

Head and neck squamous cell carcinomas (HNSCCs) are generally associated with tobacco consumption, alcohol abuse or both. Mucins (MUCs) are high‐molecular‐weight glycoproteins produced by many epithelial tissues. Many studies have indicated that MUCs play an important role in cancer metastasis. MUC6...