Perspectives on liquid biopsy for label‐free detection of “circulating tumor cells” through intelligent lab‐on‐chips

• Published in: View (Beijing, China) Vol. 1; no. 3
• Main Authors: Miccio, Lisa, Cimmino, Flora, Kurelac, Ivana, Villone, Massimiliano M., Bianco, Vittorio, Memmolo, Pasquale, Merola, Francesco, Mugnano, Martina, Capasso, Mario, Iolascon, Achille, Maffettone, Pier Luca, Ferraro, Pietro
• Format: Journal Article
• Language: English
• Published: Wiley 01.09.2020
• Subjects: cancer; CTCs detection; digital holography artificial intelligence; label‐free; liquid biopsy; microfluidics; Quantitative Phase‐Contrast Imaging

Circulating tumor cells (CTCs) are rare tumor cells released from primary, metastatic, or recurrent tumors in the peripheral blood of cancer patients. CTCs isolation from peripheral blood and their molecular characterization represent a new marker in cancer screening, a diagnostic tool called “liqui...