A double-blind comparison of carbamazepine and clomethiazole in the treatment of alcohol withdrawal syndrome
The efficacy and tolerability of carbamazepine and clomethiazole in the treatment of alcohol withdrawal symptoms were compared in a double-blind study with 68 hospitalized patients. Target withdrawal symptoms, the patient's subjective feeling and unwanted effects were recorded daily during the...
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| Published in | Acta psychiatrica Scandinavica Vol. 64; no. 3; p. 254 |
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| Main Authors | , |
| Format | Journal Article |
| Language | English |
| Published |
United States
01.09.1981
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| Subjects | |
| Online Access | Get more information |
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| Abstract | The efficacy and tolerability of carbamazepine and clomethiazole in the treatment of alcohol withdrawal symptoms were compared in a double-blind study with 68 hospitalized patients. Target withdrawal symptoms, the patient's subjective feeling and unwanted effects were recorded daily during the 1 week-treatment period. No significant differences between the two treatments could be demonstrated in the parameters studied. It appears that carbamazepine, which is widely used as an antiepileptic drug, well tolerated and not likely to produce any addiction as such, might offer a valuable alternative treatment for the symptoms of alcohol withdrawal. |
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| AbstractList | The efficacy and tolerability of carbamazepine and clomethiazole in the treatment of alcohol withdrawal symptoms were compared in a double-blind study with 68 hospitalized patients. Target withdrawal symptoms, the patient's subjective feeling and unwanted effects were recorded daily during the 1 week-treatment period. No significant differences between the two treatments could be demonstrated in the parameters studied. It appears that carbamazepine, which is widely used as an antiepileptic drug, well tolerated and not likely to produce any addiction as such, might offer a valuable alternative treatment for the symptoms of alcohol withdrawal. |
| Author | Ritola, E Malinen, L |
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| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/7034468$$D View this record in MEDLINE/PubMed |
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| Snippet | The efficacy and tolerability of carbamazepine and clomethiazole in the treatment of alcohol withdrawal symptoms were compared in a double-blind study with 68... |
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| SubjectTerms | Adult Carbamazepine - therapeutic use Chlormethiazole - therapeutic use Clinical Trials as Topic Double-Blind Method Ethanol - adverse effects Humans Male Random Allocation Substance Withdrawal Syndrome - drug therapy |
| Title | A double-blind comparison of carbamazepine and clomethiazole in the treatment of alcohol withdrawal syndrome |
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