GW5074 Increases Microglial Phagocytic Activities: Potential Therapeutic Direction for Alzheimer’s Disease - Connor, Sarah M.; Rashid, Mamunur; Ryan, Katie J.; Patel, Kruti; Boyd, Justin D.; Smith, Jennifer; Elyaman, Wassim; Bennett, David A.; Bradshaw, Elizabeth M. (Frontiers in cellular neuroscience, 2022)
Keywords: Alzheimer's disease; Apoptosis; c-RAF; Cell culture; Central nervous system; Cerebellum; Consent; Dementia; Genome-wide association studies; Genomes; Granule cells; GW5074; high content drug screening; Homeostasis; Human subjects; Immune clearance; Kinases; Memory; Microglia; Monocytes; Neurodegeneration; Neurodegenerative diseases; Neuroprotection; Neuroscience; Phagocytes; Phagocytosis; Protein-serine/threonine kinase; TREM2; Minneapolis Minnesota; New York; United States--US; GW5074; TYROBP; Alzheimer’s disease; c-RAF; high content drug screening; TREM2; microglia