Vaccine design of coronavirus spike (S) glycoprotein in chicken: immunoinformatics and computational approaches

• Published in: Translational medicine communications Vol. 5; no. 1; p. 13
• Main Authors: Awadelkareem, Eman A, Ali, Sumaia A
• Format: Journal Article
• Language: English
• Published: England BioMed Central 01.01.2020; BMC
• Subjects: Antigens; B-and T-cell epitopes; Bronchitis; Computational approaches; Coronaviruses; Disease transmission; Glycoproteins; IBV; Lymphocytes; Mortality; Pathogens; Phylogenetics; Poultry; Proteins; Spike protein; Vaccine design; Vaccines; Viruses; Sweden; Netherlands; Singapore; United Kingdom > UK; United States > US; China; India; B-and T-cell epitopes; Vaccine design; Computational approaches; Spike protein; IBV

Infectious bronchitis (IB) is a highly contagious respiratory disease in chickens and produces economic loss within the poultry industry. This disease is caused by a single stranded RNA virus belonging to Cronaviridae family. This study aimed to design a potential multi-epitopes vaccine against infe...