Arabidopsis MADS-box factor AGL16 is a negative regulator of plant response to salt stress by downregulating salt-responsive genes

• Sessile plants constantly experience environmental stresses in nature. They must have evolved effective mechanisms to balance growth with stress response. Here we report the MADS-box transcription factor AGL16 acting as a negative regulator in stress response in Arabidopsis. • Loss-of-AGL16 confer...

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Published inThe New phytologist Vol. 232; no. 6; pp. 2418 - 2439
Main Authors Zhao, Ping-Xia, Zhang, Jing, Chen, Si-Yan, Wu, Jie, Xia, Jing-Qiu, Sun, Liang-Qi, Ma, Shi-Song, Xiang, Cheng-Bin
Format Journal Article
LanguageEnglish
Published England Wiley 01.12.2021
Wiley Subscription Services, Inc
Subjects
ABA signalling
Abiotic stress
Abscisic Acid
AGL16
Arabidopsis
Arabidopsis - genetics
Arabidopsis - metabolism
Arabidopsis Proteins - genetics
Arabidopsis Proteins - metabolism
Arabidopsis thaliana
Down-regulation
Elongation
Environmental stress
Gene Expression Regulation, Plant
Genes
Genetic analysis
Germination
Germination - genetics
Homeostasis
MADS‐box
Mutants
Phenotypes
plant response
Plants, Genetically Modified - metabolism
primary root elongation
root growth
Salt Stress
Salts
Seed germination
Seedlings - metabolism
Stress response
Stress, Physiological - genetics
Transcription
transcription (genetics)
Transcription factors
Transcriptomics
Arabidopsis thaliana
MADS-box
ABA signalling
primary root elongation
salt stress
seed germination
AGL16
Online AccessGet full text
ISSN0028-646X
1469-8137
1469-8137
DOI10.1111/nph.17760

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Abstract • Sessile plants constantly experience environmental stresses in nature. They must have evolved effective mechanisms to balance growth with stress response. Here we report the MADS-box transcription factor AGL16 acting as a negative regulator in stress response in Arabidopsis. • Loss-of-AGL16 confers resistance to salt stress in seed germination, root elongation and soil-grown plants, while elevated AGL16 expression confers the opposite phenotypes compared with wild-type. However, the sensitivity to abscisic acid (ABA) in seed germination is inversely correlated with AGL16 expression levels. • Transcriptomic comparison revealed that the improved salt resistance of agl16 mutants was largely attributed to enhanced expression of stress-responsive transcriptional factors and the genes involved in ABA signalling and ion homeostasis. We further demonstrated that AGL16 directly binds to the CArG motifs in the promoter of HKT1;1, HsfA6a and MYB102 and represses their expression. Genetic analyses with double mutants also support that HsfA6a and MYB102 are target genes of AGL16. • Taken together, our results show that AGL16 acts as a negative regulator transcriptionally suppressing key components in the stress response and may play a role in balancing stress response with growth.
AbstractList • Sessile plants constantly experience environmental stresses in nature. They must have evolved effective mechanisms to balance growth with stress response. Here we report the MADS-box transcription factor AGL16 acting as a negative regulator in stress response in Arabidopsis. • Loss-of-AGL16 confers resistance to salt stress in seed germination, root elongation and soil-grown plants, while elevated AGL16 expression confers the opposite phenotypes compared with wild-type. However, the sensitivity to abscisic acid (ABA) in seed germination is inversely correlated with AGL16 expression levels. • Transcriptomic comparison revealed that the improved salt resistance of agl16 mutants was largely attributed to enhanced expression of stress-responsive transcriptional factors and the genes involved in ABA signalling and ion homeostasis. We further demonstrated that AGL16 directly binds to the CArG motifs in the promoter of HKT1;1, HsfA6a and MYB102 and represses their expression. Genetic analyses with double mutants also support that HsfA6a and MYB102 are target genes of AGL16. • Taken together, our results show that AGL16 acts as a negative regulator transcriptionally suppressing key components in the stress response and may play a role in balancing stress response with growth.
Sessile plants constantly experience environmental stresses in nature. They must have evolved effective mechanisms to balance growth with stress response. Here we report the MADS-box transcription factor AGL16 acting as a negative regulator in stress response in Arabidopsis. Loss-of-AGL16 confers resistance to salt stress in seed germination, root elongation and soil-grown plants, while elevated AGL16 expression confers the opposite phenotypes compared with wild-type. However, the sensitivity to abscisic acid (ABA) in seed germination is inversely correlated with AGL16 expression levels. Transcriptomic comparison revealed that the improved salt resistance of agl16 mutants was largely attributed to enhanced expression of stress-responsive transcriptional factors and the genes involved in ABA signalling and ion homeostasis. We further demonstrated that AGL16 directly binds to the CArG motifs in the promoter of HKT1;1, HsfA6a and MYB102 and represses their expression. Genetic analyses with double mutants also support that HsfA6a and MYB102 are target genes of AGL16. Taken together, our results show that AGL16 acts as a negative regulator transcriptionally suppressing key components in the stress response and may play a role in balancing stress response with growth.
Summary Sessile plants constantly experience environmental stresses in nature. They must have evolved effective mechanisms to balance growth with stress response. Here we report the MADS‐box transcription factor AGL16 acting as a negative regulator in stress response in Arabidopsis. Loss‐of‐AGL16 confers resistance to salt stress in seed germination, root elongation and soil‐grown plants, while elevated AGL16 expression confers the opposite phenotypes compared with wild‐type. However, the sensitivity to abscisic acid (ABA) in seed germination is inversely correlated with AGL16 expression levels. Transcriptomic comparison revealed that the improved salt resistance of agl16 mutants was largely attributed to enhanced expression of stress‐responsive transcriptional factors and the genes involved in ABA signalling and ion homeostasis. We further demonstrated that AGL16 directly binds to the CArG motifs in the promoter of HKT1;1, HsfA6a and MYB102 and represses their expression. Genetic analyses with double mutants also support that HsfA6a and MYB102 are target genes of AGL16. Taken together, our results show that AGL16 acts as a negative regulator transcriptionally suppressing key components in the stress response and may play a role in balancing stress response with growth.
Sessile plants constantly experience environmental stresses in nature. They must have evolved effective mechanisms to balance growth with stress response. Here we report the MADS‐box transcription factor AGL16 acting as a negative regulator in stress response in Arabidopsis. Loss‐of‐ AGL16 confers resistance to salt stress in seed germination, root elongation and soil‐grown plants, while elevated AGL16 expression confers the opposite phenotypes compared with wild‐type. However, the sensitivity to abscisic acid (ABA) in seed germination is inversely correlated with AGL16 expression levels. Transcriptomic comparison revealed that the improved salt resistance of agl16 mutants was largely attributed to enhanced expression of stress‐responsive transcriptional factors and the genes involved in ABA signalling and ion homeostasis. We further demonstrated that AGL16 directly binds to the CArG motifs in the promoter of HKT1;1 , HsfA6a and MYB102 and represses their expression. Genetic analyses with double mutants also support that HsfA6a and MYB102 are target genes of AGL16. Taken together, our results show that AGL16 acts as a negative regulator transcriptionally suppressing key components in the stress response and may play a role in balancing stress response with growth.
Sessile plants constantly experience environmental stresses in nature. They must have evolved effective mechanisms to balance growth with stress response. Here we report the MADS-box transcription factor AGL16 acting as a negative regulator in stress response in Arabidopsis. Loss-of-AGL16 confers resistance to salt stress in seed germination, root elongation and soil-grown plants, while elevated AGL16 expression confers the opposite phenotypes compared with wild-type. However, the sensitivity to abscisic acid (ABA) in seed germination is inversely correlated with AGL16 expression levels. Transcriptomic comparison revealed that the improved salt resistance of agl16 mutants was largely attributed to enhanced expression of stress-responsive transcriptional factors and the genes involved in ABA signalling and ion homeostasis. We further demonstrated that AGL16 directly binds to the CArG motifs in the promoter of HKT1;1, HsfA6a and MYB102 and represses their expression. Genetic analyses with double mutants also support that HsfA6a and MYB102 are target genes of AGL16. Taken together, our results show that AGL16 acts as a negative regulator transcriptionally suppressing key components in the stress response and may play a role in balancing stress response with growth.Sessile plants constantly experience environmental stresses in nature. They must have evolved effective mechanisms to balance growth with stress response. Here we report the MADS-box transcription factor AGL16 acting as a negative regulator in stress response in Arabidopsis. Loss-of-AGL16 confers resistance to salt stress in seed germination, root elongation and soil-grown plants, while elevated AGL16 expression confers the opposite phenotypes compared with wild-type. However, the sensitivity to abscisic acid (ABA) in seed germination is inversely correlated with AGL16 expression levels. Transcriptomic comparison revealed that the improved salt resistance of agl16 mutants was largely attributed to enhanced expression of stress-responsive transcriptional factors and the genes involved in ABA signalling and ion homeostasis. We further demonstrated that AGL16 directly binds to the CArG motifs in the promoter of HKT1;1, HsfA6a and MYB102 and represses their expression. Genetic analyses with double mutants also support that HsfA6a and MYB102 are target genes of AGL16. Taken together, our results show that AGL16 acts as a negative regulator transcriptionally suppressing key components in the stress response and may play a role in balancing stress response with growth.
Author Zhang, Jing
Sun, Liang-Qi
Chen, Si-Yan
Wu, Jie
Xiang, Cheng-Bin
Zhao, Ping-Xia
Xia, Jing-Qiu
Ma, Shi-Song
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  surname: Zhao
  fullname: Zhao, Ping-Xia
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  givenname: Si-Yan
  surname: Chen
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  surname: Wu
  fullname: Wu, Jie
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  fullname: Xia, Jing-Qiu
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  surname: Ma
  fullname: Ma, Shi-Song
– sequence: 8
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  surname: Xiang
  fullname: Xiang, Cheng-Bin
BackLink https://www.ncbi.nlm.nih.gov/pubmed/34605021$$D View this record in MEDLINE/PubMed
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ContentType Journal Article
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IsPeerReviewed true
IsScholarly true
Issue 6
Keywords Arabidopsis thaliana
MADS-box
ABA signalling
primary root elongation
salt stress
seed germination
AGL16
Language English
License 2021 The Authors. New Phytologist © 2021 New Phytologist Foundation.
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Snippet • Sessile plants constantly experience environmental stresses in nature. They must have evolved effective mechanisms to balance growth with stress response....
Summary Sessile plants constantly experience environmental stresses in nature. They must have evolved effective mechanisms to balance growth with stress...
Sessile plants constantly experience environmental stresses in nature. They must have evolved effective mechanisms to balance growth with stress response. Here...
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StartPage 2418
SubjectTerms ABA signalling
Abiotic stress
Abscisic Acid
AGL16
Arabidopsis
Arabidopsis - genetics
Arabidopsis - metabolism
Arabidopsis Proteins - genetics
Arabidopsis Proteins - metabolism
Arabidopsis thaliana
Down-regulation
Elongation
Environmental stress
Gene Expression Regulation, Plant
Genes
Genetic analysis
Germination
Germination - genetics
Homeostasis
MADS‐box
Mutants
Phenotypes
plant response
Plants, Genetically Modified - metabolism
primary root elongation
root growth
Salt Stress
Salts
Seed germination
Seedlings - metabolism
Stress response
Stress, Physiological - genetics
Transcription
transcription (genetics)
Transcription factors
Transcriptomics
Title Arabidopsis MADS-box factor AGL16 is a negative regulator of plant response to salt stress by downregulating salt-responsive genes
URI https://www.jstor.org/stable/27112012
https://onlinelibrary.wiley.com/doi/abs/10.1111%2Fnph.17760
https://www.ncbi.nlm.nih.gov/pubmed/34605021
https://www.proquest.com/docview/2598390820
https://www.proquest.com/docview/2579093128
https://www.proquest.com/docview/2636507558
Volume 232
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