Identification of candidate vaccine antigens of bovine hemoparasites Theileria parva and Babesia bovis by use of helper T cell clones

• Published in: Veterinary Parasitology [VET. PARASITOL.]. Vol. 57, no. 1-3. 1995 Vol. 57; no. 1; pp. 189 - 203
• Main Authors: Brown, Wendy C., Zhao, Shumin, Logan, Kathleen S., Grab, Dennis J., Rice-Ficht, Allison C.
• Format: Journal Article Conference Proceeding
• Language: English
• Published: Netherlands Elsevier B.V 01.03.1995
• Subjects: Animals; ANTIGENE; ANTIGENOS; ANTIGENS; Antigens, Protozoan - immunology; BABESIA BOVIS; Babesia bovis - immunology; Babesiosis - immunology; Babesiosis - prevention & control; BOVINAE; Cattle; Cattle Diseases; CD4-Positive T-Lymphocytes - immunology; Clone Cells; Cytokines - biosynthesis; Immune response-Protozoa; Protozoan Vaccines; T-Lymphocytes, Helper-Inducer - immunology; THEILERIA PARVA; Theileria parva - immunology; Theileriasis - immunology; Theileriasis - prevention & control; VACCIN; VACCINES; VACUNA; Immune response-Protozoa; Babesia bovis; Vaccines; Theileria parva

Current vaccines for bovine hemoparasites utilize live attenuated organisms or virulent organisms administered concurrently with antiparasitic drugs. Although such vaccines can be effective, for most hemoparasites the mechanisms of acquired resistance to challenge infection with heterologous parasit...