Optimal strategies of social distancing and vaccination against seasonal influenza

• Published in: Mathematical biosciences and engineering : MBE Vol. 10; no. 5-6; pp. 1615 - 1634
• Main Author: Shim, Eunha
• Format: Journal Article
• Language: English
• Published: United States AIMS Press 01.10.2013
• Subjects: Adolescent; Adult; Basic Reproduction Number; Child; Child, Preschool; Disease Outbreaks - prevention & control; Epidemiology; Humans; Infant; influenza; Influenza Vaccines - therapeutic use; Influenza, Human - epidemiology; Influenza, Human - prevention & control; Influenza, Human - transmission; Middle Aged; Models, Theoretical; optimal control theory; Patient Isolation; Probability; Seasons; social distancing; Time Factors; United States; vaccination; Young Adult; United States

Optimal control strategies for controlling seasonal influenza transmission in the US are of high interest, because of the significant epidemiological and economic burden of influenza. To evaluate optimal strategies of vaccination and social distancing, we used an age-structured dynamic model of seas...