New light on an old syndrome: Role of Api g 7 in mugwort pollen–related celery allergy

• Published in: Journal of allergy and clinical immunology Vol. 154; no. 3; pp. 679 - 689.e5
• Main Authors: Ballmer-Weber, Barbara K., Wangorsch, Andrea, Bures, Peter, Hanschmann, Kay-Martin, Gadermaier, Gabriele, Mattsson, Lars, Mills, Clare E.N., van Ree, Ronald, Lidholm, Jonas, Vieths, Stefan
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.09.2024
• Subjects: Adolescent; Adult; Aged; Allergens - immunology; Anaphylaxis - diagnosis; Anaphylaxis - etiology; Anaphylaxis - immunology; Antigens, Plant - immunology; Apium - adverse effects; Apium - immunology; Artemisia - immunology; birch pollen; celeriac; celery root; Child; Component-resolved diagnosis; cross-reactivity; defensin-like protein 1; Female; food challenge; Food Hypersensitivity - diagnosis; Food Hypersensitivity - immunology; Humans; Immunoglobulin E - blood; Immunoglobulin E - immunology; Male; Middle Aged; mugwort pollen; Plant Proteins - immunology; Pollen - immunology; pollen food syndrome; Rhinitis, Allergic, Seasonal - diagnosis; Rhinitis, Allergic, Seasonal - immunology; Syndrome; threshold dose; Young Adult; nsLTP; defensin-like protein 1; pollen food syndrome; OR; CCD; CI; threshold dose; mugwort pollen; Api g; LTP; cross-reactivity; Component-resolved diagnosis; celeriac; Art v; birch pollen; food challenge; CRD; Bet v; LOAEL; celery root; ED10; Pru p

[Display omitted] Celery root is known to cause severe allergic reactions in patients sensitized to mugwort pollen. We studied clinically well-characterized patients with celery allergy by IgE testing with a comprehensive panel of celery allergens to disentangle the molecular basis of what is known...