E-cadherin as an epithelial barrier protein in exhaled breath condensate

• Published in: Journal of breath research Vol. 8; no. 4; p. 046006
• Main Authors: Yuksel, Hasan, Turkeli, Ahmet, Taneli, Fatma, Horasan, Gonul Dinc, Kanik, Esra Toprak, Kizilkaya, Metehan, Gozukara, Ceyhun, Yilmaz, Ozge
• Format: Journal Article
• Language: English
• Published: England IOP Publishing 07.11.2014
• Subjects: adherens junction proteins; Adult; Asthma; Asthma - metabolism; Asthma - physiopathology; atopy; Breath Tests - methods; Cadherins - metabolism; Case-Control Studies; Child; children; Demography; E-cadherin; Eosinophils; epithelial barrier deficiency; Epithelium - metabolism; Epithelium - physiopathology; Exhalation; exhaled breath condensate; Female; Humans; Immunoglobulin E - blood; Leukocyte Count; Male; Respiratory Function Tests

Airway epithelium plays an important role as a physical barrier and a modulator of allergic response. Junctions between cells provide epithelial integrity and barrier function. The aim of this study was to investigate the influence of atopy on airway epithelial integrity in asthma and to measure E-c...