7T MRI cerebral leptomeningeal enhancement is common in relapsing-remitting multiple sclerosis and is associated with cortical and thalamic lesions

• Published in: Multiple sclerosis Vol. 26; no. 2; pp. 177 - 187
• Main Authors: Zurawski, Jonathan, Tauhid, Shahamat, Chu, Renxin, Khalid, Fariha, Healy, Brian C, Weiner, Howard L, Bakshi, Rohit
• Format: Journal Article
• Language: English
• Published: London, England SAGE Publications 01.02.2020
• Subjects: Adult; Brain - diagnostic imaging; Brain - pathology; Female; Humans; Image Interpretation, Computer-Assisted; Magnetic Resonance Imaging - methods; Male; Meninges - diagnostic imaging; Meninges - pathology; Middle Aged; Multiple Sclerosis, Relapsing-Remitting - diagnostic imaging; Multiple Sclerosis, Relapsing-Remitting - pathology; Neuroimaging - methods; 7T MRI; Leptomeningeal enhancement; cortical lesions; thalamic lesions; multiple sclerosis

Background: Meningeal inflammation may contribute to gray matter (GM) involvement in multiple sclerosis (MS) and is proposed to manifest as magnetic resonance imaging (MRI) leptomeningeal enhancement (LME). Objective: To investigate how LME relates to GM lesions in relapsing-remitting multiple scler...