SYNTAX Score Predicts the Left Ventricle Thrombus Development in Patients Undergoing Primary Percutaneous Coronary Intervention for First Anterior Myocardial Infarction

• Published in: Clinical and applied thrombosis/hemostasis Vol. 20; no. 7; pp. 698 - 705
• Main Authors: Gökdeniz, Tayyar, Boyacı, Faruk, Hatem, Engin, Aslan, Ahmet Oguz, Aykan, Ahmet Çağrı, Gül, İlker, Turan, Turhan, Kalaycıoğlu, Ezgi, Çelik, Şükrü
• Format: Journal Article
• Language: English
• Published: Los Angeles, CA SAGE Publications 01.10.2014; SAGE PUBLICATIONS, INC
• Subjects: Aged; Angioplasty; Blood clots; Echocardiography; Electrocardiography; Female; Heart attacks; Heart Ventricles - diagnostic imaging; Heart Ventricles - physiopathology; Humans; Male; Middle Aged; Myocardial Infarction - diagnostic imaging; Myocardial Infarction - physiopathology; Myocardial Infarction - surgery; Percutaneous Coronary Intervention - adverse effects; Postoperative Complications - diagnostic imaging; Postoperative Complications - physiopathology; Predictive Value of Tests; Prospective Studies; Stroke Volume; Thrombosis - diagnostic imaging; Thrombosis - etiology; Thrombosis - physiopathology; left ventricle thrombus development; SYNTAX scores; first anterior wall myocardial infarction; primary percutaneous coronary intervention
• ISSN: 1076-0296; 1938-2723
• DOI: 10.1177/1076029613478158

Objectives: The aim of this study is to investigate the relationship between left ventricular thrombus (LVT) developments and the SYNTAX score (SS) in patients undergoing primary percutaneous coronary intervention (PPCI) for first anterior wall ST-segment elevation myocardial infarction (STEMI). Methods: We enrolled 160 patients. All participants were evaluated by serial transthoracic echocardiography. Baseline clinical, echocardiographic, and procedural features of PPCI were analyzed to find predictors of LVT development. Results: The LVT was detected in 32 (20%) patients. Left ventricular ejection fraction (LVEF) and SS-I were found to be independent predictors of LVT development. Receiver–operating characteristic curve analysis revealed a cutoff value >19.5 for SS-I (area under the curve: 0.697, 95% confidence interval 0.620-0.767, P < .001) with a specificity of 45.3% and a sensitivity of 84.3%. Conclusion: High SS which was obtained through diagnostic angiogram of PPCI may be associated with LVT development in patients with first anterior wall STEMI.