Circulating microRNA-1290 as a novel diagnostic and prognostic biomarker in human colorectal cancer

• Published in: Annals of oncology Vol. 27; no. 10; pp. 1879 - 1886
• Main Authors: Imaoka, H., Toiyama, Y., Fujikawa, H., Hiro, J., Saigusa, S., Tanaka, K., Inoue, Y., Mohri, Y., Mori, T., Kato, T., Toden, S., Goel, A., Kusunoki, M.
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.10.2016
• Subjects: Aged; Biomarkers, Tumor - blood; Biomarkers, Tumor - genetics; Circulating MicroRNA - blood; Circulating MicroRNA - genetics; colorectal adenoma; colorectal cancer; Colorectal Neoplasms - blood; Colorectal Neoplasms - genetics; Colorectal Neoplasms - pathology; diagnosis; Early Detection of Cancer; Female; Gene Expression Regulation, Neoplastic; Humans; Male; MicroRNAs - blood; MicroRNAs - genetics; Middle Aged; miR-1290; Neoplasm Recurrence, Local - blood; Neoplasm Recurrence, Local - pathology; Prognosis; serum; colorectal adenoma; diagnosis; miR-1290; colorectal cancer; serum; prognosis

Circulating microRNAs (miRNAs) are attracting major interest as potential non-invasive biomarkers for colorectal cancer (CRC). This study aimed to identify a novel serum miRNA biomarker for the early detection and/or evaluating prognosis of CRC patients. Comprehensive miRNA array analysis was carrie...