The Efficacy of Recombinant FVIII Low-Dose Prophylaxis in Chinese Pediatric Patients With Severe Hemophilia A: A Retrospective Analysis From the ReCARE Study

• Published in: Clinical and applied thrombosis/hemostasis Vol. 23; no. 7; pp. 851 - 858
• Main Authors: Yao, Wanru, Xiao, Juan, Cheng, Xiaoling, Feng, Guoshuang, Li, Changgang, Zhang, Xinsheng, Hu, Qun, Xu, Weiqun, Sun, Jing, Yang, Renchi, Li, Xiaojing, Zhou, Rongfu, Lian, Shimei, Gu, Jian, Wu, Junde, Zhao, Yongqiang, Wu, Runhui
• Format: Journal Article
• Language: English
• Published: Los Angeles, CA SAGE Publications 01.10.2017; SAGE PUBLICATIONS, INC
• Subjects: Adolescent; Asian Continental Ancestry Group; Child; Child, Preschool; Factor VIII - administration & dosage; Factor VIII - therapeutic use; Hemarthrosis - drug therapy; Hemarthrosis - prevention & control; Hemophilia; Hemophilia A - complications; Hemophilia A - drug therapy; Humans; Infant; Pediatrics; Premedication - methods; Recombinant Proteins - therapeutic use; Retrospective Studies; Treatment Outcome; rFVIII-FS; annual bleeding rate; annual joint bleeding rate; low-dose prophylaxis; severe hemophilia A; China

Objective: This study explores the efficacy of recombinant factor VIII (rFVIII) low-dose prophylaxis in Chinese pediatric patients with severe hemophilia A from the Retrospective Study in Chinese Pediatric Hemophilia A Patients With rFVIII Contained Regular Prophylaxis (ReCARE) population. Methods:...