CT-Defined Prosthesis–Patient Mismatch Downgrades Frequency and Severity, and Demonstrates No Association With Adverse Outcomes After Transcatheter Aortic Valve Replacement

• Published in: JACC. Cardiovascular interventions Vol. 10; no. 15; pp. 1578 - 1587
• Main Authors: Mooney, John, Sellers, Stephanie L., Blanke, Phillip, Pibarot, Philippe, Hahn, Rebecca T., Dvir, Danny, Douglas, Pamela S., Weissman, Neil J., Kodali, Susheel K., Thourani, Vinod H., Jilaihawi, Hasan, Khalique, Omar, Smith, Craig R., Kueh, Shaw Hua, Ohana, Mickael, Grover, Romi, Naoum, Christopher, Crowley, Aaron, Jaber, Wael A., Alu, Maria C., Parvataneni, Rupa, Mack, Michael, Webb, John G., Leon, Martin B., Leipsic, Jonathon A.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 14.08.2017
• Subjects: Aged; Aged, 80 and over; Aortic Valve - diagnostic imaging; Aortic Valve - physiopathology; Aortic Valve - surgery; Aortic Valve Stenosis - diagnostic imaging; Aortic Valve Stenosis - mortality; Aortic Valve Stenosis - physiopathology; Aortic Valve Stenosis - surgery; Area Under Curve; echocardiography; Echocardiography, Doppler; Female; Heart Valve Prosthesis; Humans; Hypertrophy, Left Ventricular - diagnostic imaging; Hypertrophy, Left Ventricular - physiopathology; Kaplan-Meier Estimate; Male; Postoperative Complications - diagnostic imaging; Postoperative Complications - mortality; Postoperative Complications - physiopathology; Postoperative Complications - prevention & control; Predictive Value of Tests; Prosthesis Design; prosthesis–patient mismatch; Registries; Reproducibility of Results; Risk Assessment; Risk Factors; ROC Curve; Severity of Illness Index; Tomography, X-Ray Computed; transcatheter aortic valve replacement; Transcatheter Aortic Valve Replacement - adverse effects; Transcatheter Aortic Valve Replacement - instrumentation; Transcatheter Aortic Valve Replacement - mortality; Treatment Outcome; TTE; CI; echocardiography; LV; VTI; LVOT; PPM; TIA; TAVR; AUC; mRS; CT; AR; BSA; EOAi; STS; prosthesis–patient mismatch; transcatheter aortic valve replacement

This study sought to determine if indexed effective orifice area (EOAi), using left ventricular outflow tract measured from computed tomography (EOAiCT), reclassified prosthesis–patient mismatch (PPM) compared with conventional echocardiogram-defined measurements (EOAiTTE). PPM does not predict mort...