Predictive capacity of the brain natriuretic peptide in the screening of heart failure in a high altitude population

• Published in: Respiratory physiology & neurobiology Vol. 289; p. 103654
• Main Authors: Calderón-Gerstein, Walter, Bruno-Huamán, Astrid, Damián-Mucha, Milagros, Huayllani-Flores, Lizet
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.07.2021
• Subjects: Adult; Aged; Aged, 80 and over; Altitude; BNP; Brain natriuretic peptide; Cross-Sectional Studies; Diagnosis; Echocardiography, Doppler; Female; Heart failure; Heart Failure - blood; Heart Failure - diagnosis; Heart Failure - etiology; Humans; Hypertension, Pulmonary - blood; Hypertension, Pulmonary - diagnosis; Hypoxia; Hypoxia - complications; Lung Diseases, Interstitial - blood; Lung Diseases, Interstitial - diagnosis; Male; Middle Aged; Natriuretic Peptide, Brain - blood; Peru; Vital Capacity; Peru; Heart failure; Brain natriuretic peptide; Hypoxia; Diagnosis; BNP; Altitude

•BNP values are increased in cardiac and non – cardiac conditions at high altitude.•Usual BNP cut-off of > 100 pg/mL has good sensitivity but very low specificity for heart failure diagnosis at altitude.•Right-sided heart failure, pulmonary hypertension and interstitial lung disease are associate...