First-trimester preterm preeclampsia prediction with metabolite biomarkers: differential prediction according to maternal body mass index

• Published in: American journal of obstetrics and gynecology Vol. 229; no. 1; pp. 55.e1 - 55.e10
• Main Authors: Tuytten, Robin, Syngelaki, Argyro, Thomas, Grégoire, Panigassi, Ana, Brown, Leslie W., Ortea, Paloma, Nicolaides, Kypros H.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.07.2023
• Subjects: biomarkers; first-trimester screening; metabolites; metabolomics; prediction; preeclampsia; pregnancy; preterm; metabolomics; biomarkers; pregnancy; first-trimester screening; prediction; preterm; preeclampsia; metabolites

Prediction of preeclampsia risk is key to informing effective maternal care. Current screening for preeclampsia at 11 to 13 weeks of gestation using maternal demographic characteristics and medical history with measurements of mean arterial pressure, uterine artery pulsatility index, and serum place...