Myostatin Mutation Associated with Gross Muscle Hypertrophy in a Child

To the Editor: Schuelke et al. (June 24 issue) 1 describe a child with muscle hypertrophy in association with a mutation in the myostatin gene. Another possible case of a myostatin mutation in an exceptionally strong child was described more than 2500 years ago in Greek mythology, in the story about...

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Published inThe New England journal of medicine Vol. 351; no. 10; pp. 1030 - 1031
Main Author Williams, Marc S
Format Journal Article
LanguageEnglish
Published United States Massachusetts Medical Society 02.09.2004
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Abstract To the Editor: Schuelke et al. (June 24 issue) 1 describe a child with muscle hypertrophy in association with a mutation in the myostatin gene. Another possible case of a myostatin mutation in an exceptionally strong child was described more than 2500 years ago in Greek mythology, in the story about Hercules. As an infant, Hercules strangled a snake in each hand when the goddess Hera tried to kill him. His legendary strength was obvious from the time of his birth, and it was not the result of any exercise program. To the Editor: Schuelke et al. report a case of . . .
AbstractList To the Editor: Schuelke et al. (June 24 issue) 1 describe a child with muscle hypertrophy in association with a mutation in the myostatin gene. Another possible case of a myostatin mutation in an exceptionally strong child was described more than 2500 years ago in Greek mythology, in the story about Hercules. As an infant, Hercules strangled a snake in each hand when the goddess Hera tried to kill him. His legendary strength was obvious from the time of his birth, and it was not the result of any exercise program. To the Editor: Schuelke et al. report a case of . . .
Author Catipović, Branimir
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Cites_doi 10.1056/NEJMoa040933
10.1002/(SICI)1097-0223(199610)16:10<958::AID-PD971>3.0.CO;2-U
10.1038/387083a0
10.1038/ng0997-71
10.1002/ajmg.1320560213
10.1007/BF00441965
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References 15215484 - N Engl J Med. 2004 Jun 24;350(26):2682-8
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  publication-title: J Pediatr Endocrinol Metab
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    fullname: Butler MG
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SubjectTerms Greece, Ancient
Hercules
History, Ancient
Humans
Hypertrophy - genetics
Hypertrophy - history
Male
Muscle, Skeletal - pathology
Mutation
Myostatin
Mythology
Transforming Growth Factor beta - genetics
Title Myostatin Mutation Associated with Gross Muscle Hypertrophy in a Child
URI http://dx.doi.org/10.1056/NEJM200409023511018
https://www.ncbi.nlm.nih.gov/pubmed/15342814
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Volume 351
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