Myostatin Mutation Associated with Gross Muscle Hypertrophy in a Child

To the Editor: Schuelke et al. (June 24 issue) 1 describe a child with muscle hypertrophy in association with a mutation in the myostatin gene. Another possible case of a myostatin mutation in an exceptionally strong child was described more than 2500 years ago in Greek mythology, in the story about...

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Bibliographic Details
Published inThe New England journal of medicine Vol. 351; no. 10; pp. 1030 - 1031
Main Author Williams, Marc S
Format Journal Article
LanguageEnglish
Published United States Massachusetts Medical Society 02.09.2004
Subjects
Greece, Ancient
Hercules
History, Ancient
Humans
Hypertrophy - genetics
Hypertrophy - history
Male
Muscle, Skeletal - pathology
Mutation
Myostatin
Mythology
Transforming Growth Factor beta - genetics
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Summary:To the Editor: Schuelke et al. (June 24 issue) 1 describe a child with muscle hypertrophy in association with a mutation in the myostatin gene. Another possible case of a myostatin mutation in an exceptionally strong child was described more than 2500 years ago in Greek mythology, in the story about Hercules. As an infant, Hercules strangled a snake in each hand when the goddess Hera tried to kill him. His legendary strength was obvious from the time of his birth, and it was not the result of any exercise program. To the Editor: Schuelke et al. report a case of . . .
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ISSN:0028-4793
1533-4406
DOI:10.1056/NEJM200409023511018