Earlier vs. later time period of COVID-19 infection and emergent autoimmune signs, symptoms, and serologies

• Published in: Journal of autoimmunity Vol. 148; p. 103299
• Main Authors: Oakes, Emily G., Dillon, Eilish, Buhler, Katherine A., Guan, Hongshu, Paudel, Misti, Marks, Kathryne, Adejoorin, Ifeoluwakiisi, Yee, Jeong, Ellrodt, Jack, Tedeschi, Sara, Sparks, Jeffrey, Case, Siobhan M., Hsu, Tiffany, Solomon, Daniel H., Jonsson, A. Helena, Alexander, Roberta Vezza, Rao, Deepak A., Choi, May Y., Costenbader, Karen H.
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.09.2024
• Subjects: Adult; Aged; Antibodies, Antinuclear - blood; Antibodies, Antinuclear - immunology; Autoantibodies - blood; Autoantibodies - immunology; Autoimmune Diseases - diagnosis; Autoimmune Diseases - epidemiology; Autoimmune Diseases - immunology; Autoimmunity; B-Lymphocytes - immunology; Connective Tissue Diseases - diagnosis; Connective Tissue Diseases - epidemiology; Connective Tissue Diseases - immunology; COVID-19; COVID-19 - epidemiology; COVID-19 - immunology; Female; Humans; Immunophenotyping; Male; Middle Aged; SARS-CoV-2 - immunology; Serologic tests; Time Factors; COVID-19; Autoimmunity; Serologic tests; Immunophenotyping

Autoantibodies and autoimmune diseases after SARS-CoV-2 infection are widely reported. Given evolving variants, milder infections, and increasing population vaccination, we hypothesized that SARS-CoV-2 infection earlier in the pandemic would be associated with more autoimmune connective tissue disea...