Anesthetic Success Using Nitrous Oxide and a Combination of Lidocaine/Clonidine for the Inferior Alveolar Nerve Block and the Effects on Blood Pressure and Pulse in Patients with Symptomatic Irreversible Pulpitis: A Prospective, Randomized, Double-blind Study

• Published in: Journal of endodontics Vol. 47; no. 4; pp. 558 - 565
• Main Authors: MacDonald, Ellen, Drum, Melissa, Nusstein, John, Fowler, Sara, Beck, Mike, Reader, Al
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.04.2021
• Subjects: Anesthesia, Dental; Anesthetics, Local; Blood Pressure; Clonidine; Double-Blind Method; endodontic pain; Humans; inferior alveolar nerve block; Lidocaine; Mandibular Nerve; Nerve Block; Nitrous Oxide; Prospective Studies; Pulpitis - drug therapy; Pulpitis - surgery; symptomatic irreversible pulpitis; endodontic pain; symptomatic irreversible pulpitis; Clonidine; inferior alveolar nerve block; nitrous oxide; lidocaine

The pulpal anesthetic success rates for an inferior alveolar nerve block (IANB) alone in patients presenting with symptomatic irreversible pulpitis are less than adequate. Nitrous oxide and clonidine have shown increases in IANB success when administered individually, but their success has not been...