Systemic inflammation and delirium: important co-factors in the progression of dementia

• Published in: Biochemical Society transactions Vol. 39; no. 4; p. 945
• Main Author: Cunningham, Colm
• Format: Journal Article
• Language: English
• Published: England 01.08.2011
• Subjects: Animals; Anti-Inflammatory Agents, Non-Steroidal - therapeutic use; Central Nervous System - physiopathology; Delirium - complications; Delirium - pathology; Dementia - complications; Dementia - drug therapy; Dementia - pathology; Disease Progression; Humans; Inflammation - complications

It is widely accepted that inflammation plays some role in the progression of chronic neurodegenerative diseases such as AD (Alzheimer's disease), but its precise role remains elusive. It has been known for many years that systemic inflammatory insults can signal to the brain to induce changes...