Preanalytical, analytical (DiaSorin LIAISON) and clinical variables potentially affecting the 25-OH Vitamin D estimation

• Published in: Clinical biochemistry Vol. 45; no. 18; pp. 1652 - 1657
• Main Authors: Bianchi, Sara, Maffei, Silvia, Prontera, Concetta, Battaglia, Debora, Vassalle, Cristina
• Format: Journal Article
• Language: English
• Published: Amsterdam Elsevier Inc 01.12.2012; Elsevier
• Subjects: Analytical evaluation; Biochemistry - methods; Biological and medical sciences; Cardiovascular risk factors; Female; Humans; Hypovitaminosis D; Investigative techniques, diagnostic techniques (general aspects); LIAISON; Male; Medical sciences; Middle Aged; Regression Analysis; Seasonal variation; Vitamin D; Vitamin D - analogs & derivatives; Vitamin D - blood; Vitamin D; LIAISON; Seasonal variation; Cardiovascular risk factors; Analytical evaluation; Hypovitaminosis D; Performance evaluation; Variable; Steroid hormone; Estimation; Nutrition disorder; Hypovitaminosis; Cardiovascular disease; Epidemiology; Pre analytical step; Clinical biology; Cholecalciferol(25-hydroxy); Risk factor; Cardiovascular risk

Vitamin D (25-OHD) physiological functions have been expanded beyond traditional bone health, increasing the importance of its estimation in Laboratory Medicine, which renders validation of available methods mandatory. We evaluated some preanalytical and analytical aspects of 25-OHD determination an...