Correlations between serum hepatitis B surface antigen and hepatitis B core antibody titers and liver fibrosis in treatment-naïve CHB patients

• Published in: Journal of the Chinese Medical Association Vol. 81; no. 12; pp. 1052 - 1059
• Main Authors: Li, Min-Ran, Zheng, Huan-Wei, Ma, Shun-Mao, Liu, Yun-Yan, Qie, Lan-Xia, Li, Jun-Qing, Wang, De-Hua, Sun, Xing-Li, Ren, Gui-Fang, Zheng, Yan-Hua, Wang, Yu-Ling, Dai, Er-Hei
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Taiwan LLC 01.12.2018
• Subjects: Adult; Chronic hepatitis B; Cross-Sectional Studies; Female; Hepatitis B Antibodies - blood; Hepatitis B Core Antigens - immunology; Hepatitis B surface antigen; Hepatitis B Surface Antigens - blood; Hepatitis B virus - classification; Hepatitis B virus - genetics; Hepatitis B, Chronic - complications; Humans; Liver - pathology; Liver Cirrhosis - etiology; Liver Cirrhosis - microbiology; Liver Cirrhosis - pathology; Liver fibrosis; Logistic Models; Male; Middle Aged; Quantitative anti-HBc; Hepatitis B surface antigen; Liver fibrosis; Chronic hepatitis B; Quantitative anti-HBc
• ISSN: 1726-4901; 1728-7731; 1728-7731
• DOI: 10.1016/j.jcma.2018.05.007

Previous studies have revealed that quantitative hepatitis B surface antigen (HBsAg) or hepatitis B core antibody (qAnti-HBc) levels can be used as predictors of treatment response in both interferon-α and nucleoside analogue therapies. Few data have been published regarding the relationship between...