Combined capillary column gas chromatography/electron capture negative ion chemical ionization mass spectrometry of dihydropyridine calcium antagonists

• Published in: Biomedical & environmental mass spectrometry Vol. 13; no. 5; p. 251
• Main Authors: Tokuma, Y, Fujiwara, T, Noguchi, H
• Format: Journal Article
• Language: English
• Published: England 01.05.1986
• Subjects: Body Fluids - analysis; Calcium Channel Blockers - analysis; Chromatography, Gas; Dihydropyridines; Humans; Mass Spectrometry; Oxidation-Reduction; Pyridines - analysis

Several dihydropyridine calcium antagonists showed intense [M]-. ion peaks as the base peaks and a few fragment peaks in the electron capture negative ion chemical ionization mass spectra. The peak intensities of the [M]-. ion of these antagonists were about 100 times as high as those of the most ab...