Intermittent fasting from dawn to sunset for 30 consecutive days is associated with anticancer proteomic signature and upregulates key regulatory proteins of glucose and lipid metabolism, circadian clock, DNA repair, cytoskeleton remodeling, immune system and cognitive function in healthy subjects - Mindikoglu, Ayse L.; Abdulsada, Mustafa M.; Jain, Antrix; Choi, Jong Min; Jalal, Prasun K.; Devaraj, Sridevi; Mezzari, Melissa P.; Petrosino, Joseph F.; Opekun, Antone R.; Jung, Sung Yun (Journal of proteomics, 2020)
Keywords: Alzheimer disease; animal models; blood serum; circadian clocks; cognition; cytoskeleton; diabetes; DNA repair; fasting; gene expression regulation; glucose; humans; immune system; inflammation; insulin; lipid metabolism; low calorie diet; metabolic syndrome; neoplasms; obesity; proteome; proteomics; regulatory proteins; tandem mass spectrometry; therapeutics; ultra-performance liquid chromatography; weight loss