Early focal brain injury after subarachnoid hemorrhage correlates with spreading depolarizations

• Published in: Neurology Vol. 92; no. 4; p. e326
• Main Authors: Eriksen, Nina, Rostrup, Egill, Fabricius, Martin, Scheel, Michael, Major, Sebastian, Winkler, Maren K L, Bohner, Georg, Santos, Edgar, Sakowitz, Oliver W, Kola, Vasilis, Reiffurth, Clemens, Hartings, Jed A, Vajkoczy, Peter, Woitzik, Johannes, Martus, Peter, Lauritzen, Martin, Pakkenberg, Bente, Dreier, Jens P
• Format: Journal Article
• Language: English
• Published: United States 22.01.2019
• Subjects: Aged; Brain Injuries - etiology; Cortical Spreading Depression - physiology; Electrocorticography; Female; Humans; Male; Middle Aged; Subarachnoid Hemorrhage - complications; Subarachnoid Hemorrhage - diagnostic imaging; Time Factors; Tomography Scanners, X-Ray Computed

To investigate whether spreading depolarization (SD)-related variables at 2 different time windows (days 1-4 and 5-8) after aneurysmal subarachnoid hemorrhage (aSAH) correlate with the stereologically determined volume of early focal brain injury on the preinterventional CT scan. In this observation...