Liquid chromatography in pharmaceutical analysis VI: determination of dantrolene sodium in a dosage form

• Published in: Journal of pharmaceutical sciences Vol. 66; no. 2; p. 286
• Main Authors: Saxena, S J, Honigberg, I L, Stewart, J T, Keene, G R, Vallner, J J
• Format: Journal Article
• Language: English
• Published: United States 01.02.1977
• Subjects: Capsules - analysis; Chromatography, High Pressure Liquid; Dantrolene - analysis; Hydantoins - analysis; Spectrometry, Fluorescence

Operating conditions are described for the qualitative and quantitative determination of dantrolene sodium by high-pressure liquid chromatography. A 10-mum porous silica column was employed, using carbon tetrachloride-dimethylformamide (90:10) as the mobile phase. The flow rate was 2.0 ml/min (1800...