The effect of cryopreservation on canine menisci: a biochemical, morphologic, and biomechanical evaluation

• Published in: Journal of orthopaedic research Vol. 6; no. 1; p. 1
• Main Authors: Arnoczky, S P, McDevitt, C A, Schmidt, M B, Mow, V C, Warren, R F
• Format: Journal Article
• Language: English
• Published: United States 1988
• Subjects: Animals; Cell Survival; Dimethyl Sulfoxide; Dogs; Freezing; Glycosaminoglycans - biosynthesis; Menisci, Tibial - cytology; Menisci, Tibial - metabolism; Menisci, Tibial - physiology; Stress, Mechanical; Sulfur Radioisotopes - metabolism; Tensile Strength; Time Factors; Tissue Preservation - methods

This study evaluated the effect of cryopreservation on the structural organization, biosynthetic activity, and material properties of canine menisci. The menisci were cryopreserved by incubating them in a 4% solution of dimethyl sulfoxide (DMSO) in physiologic media and freezing them to -100 degrees...