Multistep Approach Points to Compounds Responsible for the Biological Activity and Safety of Hydrolates from Nine Lamiaceae Medicinal Plants on Human Skin Fibroblasts

• Published in: Antioxidants Vol. 12; no. 11; p. 1988
• Main Authors: Smiljanić, Katarina, Prodić, Ivana, Trifunovic, Sara, Krstić Ristivojević, Maja, Aćimović, Milica, Stanković Jeremić, Jovana, Lončar, Biljana, Tešević, Vele
• Format: Journal Article
• Language: English
• Published: Basel MDPI AG 01.11.2023
• Subjects: Acids; anti-proliferative effects; Antioxidants; Biological activity; Borneol; Chromatography; Cineole; Cosmetics; Cytotoxicity; DNA biosynthesis; Essential oils; Fibroblasts; Geranial; Hair; Herbal medicine; hydrolates; Lamiaceae; Linalool; Mass spectrometry; Medicinal plants; natural cosmetics; Neral; Oils & fats; Peptides; proliferative effects; Scientific imaging; Skin; skin fibroblast viability; STITCH database; Terpinene; Terpinene-4-ol; Terpineol; Thymol; Viability; VOCs; Volatile organic compounds; Wound healing; United States > US

As byproducts of essential oil distillation, hydrolates are used in natural cosmetics/biomedicine due to their beneficial skin effects. However, data on their safety with relevant biological targets, such as human skin cells, are scarce. Therefore, we have tested nine hydrolates from the Lamiaceae f...