Ubiquitin-proteasome-mediated local protein degradation and synaptic plasticity

A proteolytic pathway in which attachment of a small protein, ubiquitin, marks the substrates for degradation by a multi-subunit complex called the proteasome has been shown to function in synaptic plasticity and in several other physiological processes of the nervous system. Attachment of ubiquitin...

Full description

Saved in:
Bibliographic Details
Published inProgress in neurobiology Vol. 73; no. 5; pp. 311 - 357
Main Author Hegde, Ashok N.
Format Journal Article
LanguageEnglish
Published England 01.08.2004
Subjects
Animals
Humans
Neuronal Plasticity - physiology
Proteasome Endopeptidase Complex - physiology
Protein Denaturation
Synapses - enzymology
Synapses - metabolism
Synapses - physiology
Ubiquitin - physiology
Online AccessGet full text

Cover

Abstract A proteolytic pathway in which attachment of a small protein, ubiquitin, marks the substrates for degradation by a multi-subunit complex called the proteasome has been shown to function in synaptic plasticity and in several other physiological processes of the nervous system. Attachment of ubiquitin to protein substrates occurs through a series of highly specific and regulated steps. Degradation by the proteasome is subject to multiple levels of regulation as well. How does the ubiquitin-proteasome pathway contribute to synaptic plasticity? Long-lasting, protein synthesis-dependent, changes in the synaptic strength occur through activation of molecular cascades in the nucleus in coordination with signaling events in specific synapses. Available evidence indicates that ubiquitin-proteasome-mediated degradation has a role in the molecular mechanisms underlying synaptic plasticity that operate in the nucleus as well as at the synapse. Since the ubiquitin-proteasome pathway has been shown to be versatile in having roles in addition to proteolysis in several other cellular processes relevant to synaptic plasticity, such as endocytosis and transcription, this pathway is highly suited for a localized role in the neuron. Because of its numerous roles, malfunctioning of this pathway leads to several diseases and disorders of the nervous system. In this review, I examine the ubiquitin-proteasome pathway in detail and describe the role of regulated proteolysis in long-term synaptic plasticity. Also, using synaptic tagging theory of synapse-specific plasticity, I provide a model on the possible roles and regulation of local protein degradation by the ubiquitin-proteasome pathway.
AbstractList A proteolytic pathway in which attachment of a small protein, ubiquitin, marks the substrates for degradation by a multi-subunit complex called the proteasome has been shown to function in synaptic plasticity and in several other physiological processes of the nervous system. Attachment of ubiquitin to protein substrates occurs through a series of highly specific and regulated steps. Degradation by the proteasome is subject to multiple levels of regulation as well. How does the ubiquitin-proteasome pathway contribute to synaptic plasticity? Long-lasting, protein synthesis-dependent, changes in the synaptic strength occur through activation of molecular cascades in the nucleus in coordination with signaling events in specific synapses. Available evidence indicates that ubiquitin-proteasome-mediated degradation has a role in the molecular mechanisms underlying synaptic plasticity that operate in the nucleus as well as at the synapse. Since the ubiquitin-proteasome pathway has been shown to be versatile in having roles in addition to proteolysis in several other cellular processes relevant to synaptic plasticity, such as endocytosis and transcription, this pathway is highly suited for a localized role in the neuron. Because of its numerous roles, malfunctioning of this pathway leads to several diseases and disorders of the nervous system. In this review, I examine the ubiquitin-proteasome pathway in detail and describe the role of regulated proteolysis in long-term synaptic plasticity. Also, using synaptic tagging theory of synapse-specific plasticity, I provide a model on the possible roles and regulation of local protein degradation by the ubiquitin-proteasome pathway.A proteolytic pathway in which attachment of a small protein, ubiquitin, marks the substrates for degradation by a multi-subunit complex called the proteasome has been shown to function in synaptic plasticity and in several other physiological processes of the nervous system. Attachment of ubiquitin to protein substrates occurs through a series of highly specific and regulated steps. Degradation by the proteasome is subject to multiple levels of regulation as well. How does the ubiquitin-proteasome pathway contribute to synaptic plasticity? Long-lasting, protein synthesis-dependent, changes in the synaptic strength occur through activation of molecular cascades in the nucleus in coordination with signaling events in specific synapses. Available evidence indicates that ubiquitin-proteasome-mediated degradation has a role in the molecular mechanisms underlying synaptic plasticity that operate in the nucleus as well as at the synapse. Since the ubiquitin-proteasome pathway has been shown to be versatile in having roles in addition to proteolysis in several other cellular processes relevant to synaptic plasticity, such as endocytosis and transcription, this pathway is highly suited for a localized role in the neuron. Because of its numerous roles, malfunctioning of this pathway leads to several diseases and disorders of the nervous system. In this review, I examine the ubiquitin-proteasome pathway in detail and describe the role of regulated proteolysis in long-term synaptic plasticity. Also, using synaptic tagging theory of synapse-specific plasticity, I provide a model on the possible roles and regulation of local protein degradation by the ubiquitin-proteasome pathway.
A proteolytic pathway in which attachment of a small protein, ubiquitin, marks the substrates for degradation by a multi-subunit complex called the proteasome has been shown to function in synaptic plasticity and in several other physiological processes of the nervous system. Attachment of ubiquitin to protein substrates occurs through a series of highly specific and regulated steps. Degradation by the proteasome is subject to multiple levels of regulation as well. How does the ubiquitin-proteasome pathway contribute to synaptic plasticity? Long-lasting, protein synthesis-dependent, changes in the synaptic strength occur through activation of molecular cascades in the nucleus in coordination with signaling events in specific synapses. Available evidence indicates that ubiquitin-proteasome-mediated degradation has a role in the molecular mechanisms underlying synaptic plasticity that operate in the nucleus as well as at the synapse. Since the ubiquitin-proteasome pathway has been shown to be versatile in having roles in addition to proteolysis in several other cellular processes relevant to synaptic plasticity, such as endocytosis and transcription, this pathway is highly suited for a localized role in the neuron. Because of its numerous roles, malfunctioning of this pathway leads to several diseases and disorders of the nervous system. In this review, I examine the ubiquitin-proteasome pathway in detail and describe the role of regulated proteolysis in long-term synaptic plasticity. Also, using synaptic tagging theory of synapse-specific plasticity, I provide a model on the possible roles and regulation of local protein degradation by the ubiquitin-proteasome pathway.
Author Hegde, Ashok N.
Author_xml – sequence: 1
  givenname: Ashok N.
  surname: Hegde
  fullname: Hegde, Ashok N.
BackLink https://www.ncbi.nlm.nih.gov/pubmed/15312912$$D View this record in MEDLINE/PubMed
BookMark eNqFkb1PwzAQxT2A-Cj8C5CJLeEcJ046MKCKL6lSFzpbl_iCXKV2iJ2h_z2m5UNiYXrD_d7p7r1zdmSdJcauOWQcuLzdZIOlaXSNcVkOUGRQZgDlETsDATwFqPNTdu79BgCkAHHCTnkpeD7n-RlbrRvzPplgbDqMLhB6t6V0S9pgIJ30rsU-2U-MTTS9jagxGGcTtDrxO4tDMG0y9OijmrC7YMcd9p4uv3TG1o8Pr4vndLl6elncL9O2ABnSrsYWOoKmKDsJukFd1V0nqKp1M59zoFaQJCkEyEYDVrwoKup4ybGisi5QzNjNYW-87X0iH9TW-Jb6Hi25ySspq3lR5fJfkNcgIlxH8OoLnJr4vxpGs8Vxp76zikB1ANrReT9S94uA-mxCbdRPE-qzCQWlik1E590fZ4xqH2MY0fT_-j8AUE-X8g
CitedBy_id crossref_primary_10_1016_j_neuron_2010_11_006
crossref_primary_10_1091_mbc_e05_08_0794
crossref_primary_10_1101_lm_984508
crossref_primary_10_1007_s00702_009_0240_y
crossref_primary_10_1038_ncomms7687
crossref_primary_10_1016_j_mcn_2006_11_019
crossref_primary_10_1016_j_neuron_2006_07_005
crossref_primary_10_1016_j_bbagrm_2010_07_006
crossref_primary_10_3390_antibiotics9110757
crossref_primary_10_1007_s11481_009_9168_0
crossref_primary_10_1016_j_isci_2020_101132
crossref_primary_10_1016_j_neures_2006_04_006
crossref_primary_10_1007_s12264_022_00888_9
crossref_primary_10_1016_j_neuroscience_2012_06_021
crossref_primary_10_1016_j_neuropharm_2018_01_043
crossref_primary_10_1074_jbc_M111_273854
crossref_primary_10_1310_tsr1604_282
crossref_primary_10_1016_j_neulet_2006_09_015
crossref_primary_10_1074_jbc_M109_021956
crossref_primary_10_3390_fishes8040187
crossref_primary_10_1074_jbc_RA119_009618
crossref_primary_10_1560_742P_ET1J_8RLC_2JYV
crossref_primary_10_1111_j_1471_4159_2011_07221_x
crossref_primary_10_1089_ars_2011_4082
crossref_primary_10_1016_j_neurobiolaging_2005_04_016
crossref_primary_10_1016_j_jnutbio_2017_09_016
crossref_primary_10_1089_jir_2005_25_617
crossref_primary_10_3389_fcell_2023_1124907
crossref_primary_10_1093_pcp_pci144
crossref_primary_10_1080_00268976_2019_1705412
crossref_primary_10_3389_fnmol_2019_00109
crossref_primary_10_1016_j_celrep_2022_111588
crossref_primary_10_1016_j_neuint_2011_08_009
crossref_primary_10_3390_cells8010034
crossref_primary_10_3389_fnbeh_2021_807215
crossref_primary_10_3389_fncel_2018_00487
crossref_primary_10_1111_j_1464_410X_2009_08475_x
crossref_primary_10_1016_j_bbagrm_2010_11_006
crossref_primary_10_3389_fnagi_2022_1028148
crossref_primary_10_3390_cells10123501
crossref_primary_10_1111_j_1600_0854_2005_00323_x
crossref_primary_10_1186_1472_6882_12_241
crossref_primary_10_1111_j_1601_183X_2007_00338_x
crossref_primary_10_1017_S0016672309990152
crossref_primary_10_1083_jcb_200511028
crossref_primary_10_1016_j_neuint_2005_11_003
crossref_primary_10_1155_2013_432057
crossref_primary_10_3389_fnins_2022_824871
crossref_primary_10_1016_j_pmrj_2010_09_011
crossref_primary_10_1242_jcs_207027
crossref_primary_10_1016_j_neuron_2011_10_011
crossref_primary_10_1523_JNEUROSCI_1684_06_2006
crossref_primary_10_1111_j_1471_4159_2011_07588_x
crossref_primary_10_1242_jcs_000166
crossref_primary_10_1016_j_neulet_2010_02_033
crossref_primary_10_1016_j_brainres_2006_06_053
crossref_primary_10_1016_j_neuroscience_2010_06_032
crossref_primary_10_1002_bies_20379
crossref_primary_10_1002_syn_20994
crossref_primary_10_1016_j_neurobiolaging_2006_11_008
crossref_primary_10_1155_2012_825364
crossref_primary_10_1073_pnas_0801605105
crossref_primary_10_1534_genetics_107_082487
crossref_primary_10_1042_BST0371375
crossref_primary_10_1111_j_1582_4934_2008_00402_x
crossref_primary_10_1007_s10519_006_9053_z
crossref_primary_10_1038_icb_2010_45
crossref_primary_10_1016_j_nlm_2016_09_003
crossref_primary_10_1016_j_bbamcr_2014_08_006
crossref_primary_10_2353_ajpath_2010_090390
crossref_primary_10_1016_j_tins_2007_08_005
crossref_primary_10_1002_cne_20943
crossref_primary_10_1038_s41380_023_02251_4
crossref_primary_10_1016_j_neuroscience_2007_04_022
crossref_primary_10_3389_fnmol_2014_00096
crossref_primary_10_1038_embor_2008_229
crossref_primary_10_1093_hmg_ddae115
crossref_primary_10_1016_j_expneurol_2009_06_004
crossref_primary_10_1016_j_neuint_2008_07_010
crossref_primary_10_3389_fnagi_2019_00324
crossref_primary_10_1016_j_plantsci_2008_02_010
crossref_primary_10_1038_nrn2963
crossref_primary_10_1038_sj_mp_4001875
crossref_primary_10_1093_hmg_ddu422
crossref_primary_10_1096_fj_201902844RR
crossref_primary_10_1007_s11684_008_0013_2
crossref_primary_10_1093_jnen_nlx104
crossref_primary_10_1007_s11064_005_7047_5
crossref_primary_10_1016_j_mehy_2006_02_023
crossref_primary_10_1126_science_1147570
crossref_primary_10_1016_j_molimm_2012_07_003
crossref_primary_10_1074_jbc_M411491200
crossref_primary_10_3390_ijms26030966
crossref_primary_10_1038_cr_2016_86
crossref_primary_10_1002_cne_24063
crossref_primary_10_1093_cercor_bhv084
crossref_primary_10_1016_j_molmed_2017_11_006
crossref_primary_10_1523_JNEUROSCI_4573_05_2006
crossref_primary_10_1016_j_neuint_2009_08_013
crossref_primary_10_1101_lm_1504010
crossref_primary_10_1016_j_neuroscience_2009_11_066
crossref_primary_10_1134_S1819712409030027
crossref_primary_10_1523_JNEUROSCI_6094_08_2009
crossref_primary_10_1016_j_neuropharm_2008_04_015
crossref_primary_10_1523_JNEUROSCI_3291_13_2014
crossref_primary_10_1016_j_cell_2006_12_047
crossref_primary_10_1016_j_jip_2021_107602
crossref_primary_10_1523_JNEUROSCI_1571_07_2007
Cites_doi 10.1016/0092-8674(95)90240-6
10.1038/329062a0
10.1128/MCB.22.20.6946-6958.2002
10.1074/jbc.274.48.33959
10.1038/nn811
10.1093/hmg/ddg269
10.1016/S0006-8993(02)03729-0
10.1126/science.1082475
10.1016/S0968-0004(99)01420-6
10.1093/brain/119.5.1633
10.1016/S1097-2765(00)80020-9
10.1101/lm.4.6.496
10.1046/j.1460-9568.1999.00713.x
10.1073/pnas.1835674100
10.1016/S0960-9822(03)00332-4
10.1093/brain/121.7.1329
10.1126/science.1063866
10.1016/S0896-6273(03)00206-X
10.1126/science.1067020
10.1523/JNEUROSCI.19-11-04314.1999
10.1074/jbc.M209626200
10.1016/S1534-5807(02)00220-4
10.1074/jbc.M008761200
10.1016/S0014-5793(99)01072-8
10.1006/scdb.2000.0164
10.1074/jbc.273.16.9734
10.1016/0896-6273(91)90166-W
10.1038/365176a0
10.1126/science.279.5348.242
10.1016/S0896-6273(04)00073-X
10.1101/SQB.1990.055.01.045
10.1074/jbc.275.2.875
10.1093/emboj/18.20.5528
10.1074/jbc.M003949200
10.1074/jbc.M111958200
10.1074/jbc.272.45.28438
10.1016/S0092-8674(00)81653-0
10.1034/j.1600-0854.2003.00115.x
10.1128/MCB.23.9.3363-3372.2003
10.1038/35050524
10.1002/ana.410370516
10.1016/S0083-6729(08)61037-7
10.1016/S0092-8674(01)00633-X
10.1038/nsb906
10.1073/pnas.93.24.13797
10.1146/annurev.cb.07.110191.000325
10.1016/S1357-2725(99)00042-4
10.1016/S0896-6273(00)80874-0
10.1038/sj.onc.1207390
10.1038/416183a
10.1046/j.1471-4159.2003.01650.x
10.1074/jbc.272.14.9002
10.1126/science.283.5409.1923
10.1002/j.1460-2075.1992.tb05308.x
10.1016/S0092-8674(02)00657-8
10.1016/S0092-8674(00)00126-4
10.1016/S0962-8924(00)01834-1
10.1101/gad.877901
10.1146/annurev.biochem.67.1.425
10.1146/annurev.cb.11.110195.002035
10.1073/pnas.92.20.9303
10.1016/S0960-9822(98)70088-0
10.1038/nn0901-908
10.1016/S0959-4388(99)80013-0
10.1016/S0306-4522(02)00566-3
10.1016/S0896-6273(00)80686-8
10.1042/bj3300683
10.1042/bst0200631
10.1038/sj.onc.1200872
10.1034/j.1600-0854.2002.030204.x
10.1038/386463a0
10.1046/j.1460-9568.2002.02106.x
10.1038/ncb758
10.1093/emboj/cdf510
10.1093/nar/19.5.1035
10.1038/366313a0
10.1016/S0896-6273(02)01166-2
10.1016/S1097-2765(01)00250-7
10.1038/nature01276
10.1073/pnas.96.16.9124
10.1126/science.1060627
10.1093/emboj/20.24.7052
10.1126/science.1069989
10.1523/JNEUROSCI.22-07-02718.2002
10.1074/jbc.M211796200
10.1016/S1534-5807(02)00186-7
10.1016/S0896-6273(03)00606-8
10.1126/science.1074069
10.1126/science.279.5354.1219
10.1128/MCB.20.17.6568-6578.2000
10.1523/JNEUROSCI.17-10-03455.1997
10.1073/pnas.91.8.3196
10.1515/BC.2000.121
10.1038/nature01273
10.1091/mbc.11.10.3425
10.1006/dbio.1994.1342
10.1523/JNEUROSCI.21-02-00382.2001
10.1093/emboj/18.1.22
10.1073/pnas.031470698
10.1016/S1534-5807(02)00219-8
10.1074/jbc.M207991200
10.1016/S0968-0004(98)01217-1
10.1146/annurev.neuro.20.1.157
10.1016/S0968-0004(02)02190-4
10.1016/0896-6273(93)90182-Q
10.1111/j.1471-4159.2004.02707.x
10.1146/annurev.bi.65.070196.004101
10.1242/jcs.110.15.1793
10.1073/pnas.93.15.8040
10.1073/pnas.96.20.11364
10.1038/ng1006
10.1002/j.1460-2075.1991.tb07940.x
10.1021/bi001815n
10.1523/JNEUROSCI.15-11-07592.1995
10.1074/jbc.C300096200
10.1038/ncb983
10.1046/j.1471-4159.1999.0731075.x
10.1038/nrn942
10.1016/0092-8674(94)90400-6
10.1016/0012-1606(92)90210-8
10.1038/13178
10.1111/j.1749-6632.2000.tb06901.x
10.1016/0006-8993(71)90302-7
10.1126/science.6144182
10.1046/j.1471-4159.1999.0732415.x
10.1093/emboj/16.15.4540
10.1091/mbc.12.8.2556
10.1038/26652
10.1016/S0092-8674(00)81400-2
10.1093/nar/15.2.443
10.1002/(SICI)1097-4652(200001)182:1<1::AID-JCP1>3.0.CO;2-V
10.1093/emboj/17.17.5001
10.1126/science.1585177
10.1016/S1357-2725(02)00392-8
10.1074/jbc.M102755200
10.1126/science.278.5337.455
10.1523/JNEUROSCI.14-05-03166.1994
10.1074/jbc.M008054200
10.1093/emboj/20.18.5187
10.1016/S0021-9258(18)53218-X
10.1016/S1097-2765(02)00682-2
10.1016/S0021-9258(18)48343-3
10.1128/MCB.13.2.775
10.1126/science.284.5413.499
10.1046/j.1460-9568.2000.00991.x
10.1038/ng0197-70
10.1016/S0021-9258(18)89632-6
10.1016/0092-8674(94)90399-9
10.1128/MCB.18.6.3149
10.1074/jbc.M101968200
10.1016/S0378-1119(99)00197-3
10.1152/physrev.00027.2001
10.1038/416535a
10.1002/j.1460-2075.1985.tb03825.x
10.1126/science.274.5284.99
10.1016/0014-4886(73)90108-8
10.1016/S0896-6273(02)00749-3
10.1038/385533a0
10.1038/nature01803
10.1126/science.273.5282.1725
10.1016/S0361-9230(01)00611-6
10.1091/mbc.12.5.1293
10.1074/jbc.271.26.15608
10.1016/S0960-9822(99)80352-2
10.1146/annurev.ph.55.030193.002145
10.1146/annurev.immunol.18.1.621
10.1083/jcb.150.1.119
10.1074/jbc.270.46.27687
10.1046/j.1471-4159.2000.0742607.x
10.1016/S0960-9822(99)80091-8
10.1016/S0968-0004(03)00113-0
10.1007/BF00990967
10.1002/cne.902380210
10.1093/emboj/20.24.7096
10.1038/312101a0
10.1111/j.1749-6632.1991.tb25924.x
10.1101/gad.12.23.3663
10.1016/0006-8993(90)90148-5
10.1016/S0092-8674(00)80574-7
10.1038/77060
10.1006/abbi.2000.2178
10.1172/JCI5713
10.1016/S0014-5793(98)00676-0
10.1046/j.1471-4159.1998.71031298.x
10.1038/35055162
10.1016/S0896-6273(01)00355-5
10.1074/jbc.275.12.8945
10.1126/science.7725097
10.1523/JNEUROSCI.20-13-05115.2000
10.1089/oli.1.2000.10.17
10.1074/jbc.272.20.13403
10.1016/S0092-8674(00)81634-7
10.1016/S0960-9822(00)00398-5
10.1038/nature01802
10.1016/S0960-9822(02)00900-4
10.1074/jbc.M001697200
10.1038/35085597
10.1073/pnas.92.7.2563
10.1093/hmg/10.10.1049
10.1038/416451a
10.1038/25159
10.1016/S0028-3908(98)00040-9
10.1016/S1097-2765(03)00193-X
10.1083/jcb.150.4.905
10.1083/jcb.141.6.1415
10.1093/hmg/8.5.763
10.1093/emboj/18.11.3007
10.1523/JNEUROSCI.21-22-08772.2001
10.1002/bies.10320
10.1136/jnnp.58.5.598
10.1016/S0896-6273(00)80198-1
10.1016/j.cub.2003.10.028
10.1016/0006-8993(94)91578-4
10.1016/S0960-9822(03)00338-5
10.1126/science.7732382
10.1016/S0169-328X(00)00021-8
10.1126/science.275.5298.400
10.1126/science.284.5414.601
10.1016/S0166-2236(97)01189-2
10.1101/gad.12.7.901
10.1074/jbc.270.4.1850
10.1016/S0021-9258(17)31904-X
10.1038/nrn961
10.1126/science.2544030
10.1074/jbc.M203300200
10.1074/jbc.M107857200
10.1016/S0896-6273(01)00551-7
10.1016/S0896-6273(00)80596-6
10.1146/annurev.biochem.68.1.583
10.1038/12647
10.1093/emboj/19.20.5502
10.1093/emboj/21.7.1833
10.1126/science.287.5452.501
10.1016/S1097-2765(00)80156-2
10.1016/0306-4522(92)90336-Z
10.1016/S0092-8674(02)00630-X
10.1091/mbc.10.8.2583
10.1126/science.1585176
10.1073/pnas.97.15.8501
10.1097/00041552-200009000-00012
10.1074/jbc.M102121200
10.1002/cne.902530405
10.1016/S0092-8674(00)81752-3
10.1128/MCB.14.5.3158
10.1002/j.1460-2075.1988.tb02921.x
10.1038/nature01811
10.1007/BF00237559
10.1073/pnas.88.1.139
10.1016/S1097-2765(02)00826-2
10.1093/emboj/19.1.94
10.1038/26506
10.1016/S0074-7696(08)61056-6
10.1038/nature01720
10.1104/pp.012781
10.1021/bi972274d
10.1016/S0092-8674(00)81603-7
10.1186/1471-2091-3-28
10.1083/jcb.153.4.649
10.1016/S0968-0004(03)00092-6
10.1093/embo-reports/kve184
10.1038/345718a0
10.1038/35086595
10.1073/pnas.88.1.258
10.1038/ncb746
10.1126/science.278.5344.1806
10.1016/S1097-2765(02)00802-X
10.1016/S1097-2765(02)00638-X
10.1016/S0092-8674(01)00434-2
10.1073/pnas.96.5.1858
10.1073/pnas.050007597
10.1016/S1097-2765(00)80231-2
10.1038/35050509
10.1016/0092-8674(94)90193-7
10.1073/pnas.240347797
10.1002/j.1460-2075.1993.tb06080.x
10.1006/dbio.2001.0153
10.1016/0896-6273(92)90037-E
10.1016/S0960-9822(01)00487-0
10.1038/nn1013
10.1126/science.1063127
10.1038/ncb1001-e232
10.1002/j.1460-2075.1996.tb00560.x
10.1126/science.1077209
10.1038/384432a0
10.1093/emboj/17.8.2208
10.1006/bbrc.1996.1692
10.1074/jbc.M107706200
10.1074/jbc.M308947200
10.1016/S0968-0004(98)01222-5
10.1046/j.1471-4159.2000.0750436.x
10.1016/S0960-9822(03)00064-2
10.1016/S0092-8674(00)80484-5
10.1038/ng0197-74
10.1038/42276
10.1002/mds.870060207
10.1073/pnas.90.16.7436
10.1038/28660
10.1016/S0968-0004(03)00055-0
10.1038/35019643
10.1038/416345a
10.1074/jbc.M007991200
10.1038/35107009
10.1093/emboj/cdf493
10.1038/35014629
10.1146/annurev.biophys.28.1.295
10.1093/emboj/16.21.6325
10.1074/jbc.M308285200
10.1074/jbc.273.37.24057
10.1126/stke.2003.190.pe26
10.1074/jbc.274.38.27299
10.1021/bi00044a032
10.1016/S0896-6273(00)80199-3
10.1016/S0092-8674(00)80575-9
10.1016/S0014-5793(00)01098-X
10.1016/S0896-6273(00)00100-8
10.1126/science.1062079
10.1007/BF00711089
10.2741/furlow
10.1038/33416
10.1038/sj.embor.embor764
10.1093/emboj/17.5.1336
10.1016/0092-8674(95)90241-4
10.1126/science.290.5496.1574
10.1126/science.274.5290.1199
10.1074/jbc.275.3.1575
10.1126/science.292.5521.1552
10.1073/pnas.042575699
10.1002/cne.902530404
10.1016/S1097-2765(00)80037-4
10.1126/science.6828885
10.1016/S0968-0004(01)01835-7
10.1016/S0092-8674(00)00077-5
10.1016/S0896-6273(03)00295-2
10.1091/mbc.8.5.825
10.1523/JNEUROSCI.15-01-00001.1995
10.1016/S0092-8674(00)80188-9
10.1126/science.278.5337.460
10.1016/S0896-6273(03)00687-1
10.1002/j.1460-2075.1996.tb00912.x
10.1016/0014-4886(67)90029-5
10.1016/S1097-2765(00)80056-8
10.1016/0968-0004(96)10036-0
10.1038/361453a0
10.1146/annurev.bi.61.070192.003553
10.1046/j.1471-4159.2003.01642.x
10.1016/S0021-9258(18)42714-7
10.1002/pro.5560070521
10.1046/j.0953-816x.2001.01806.x
10.1038/nrn983
10.1038/ncb1106
10.1073/pnas.96.20.11317
10.1126/science.1075901
10.1038/ncb1107
10.1016/S0896-6273(02)00795-X
ContentType Journal Article
DBID AAYXX
CITATION
CGR
CUY
CVF
ECM
EIF
NPM
7TK
7X8
DOI 10.1016/j.pneurobio.2004.05.005
DatabaseName CrossRef
Medline
MEDLINE
MEDLINE (Ovid)
MEDLINE
MEDLINE
PubMed
Neurosciences Abstracts
MEDLINE - Academic
DatabaseTitle CrossRef
MEDLINE
Medline Complete
MEDLINE with Full Text
PubMed
MEDLINE (Ovid)
Neurosciences Abstracts
MEDLINE - Academic
DatabaseTitleList MEDLINE - Academic
MEDLINE
Neurosciences Abstracts
Database_xml – sequence: 1
  dbid: NPM
  name: PubMed
  url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
– sequence: 2
  dbid: EIF
  name: MEDLINE
  url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search
  sourceTypes: Index Database
DeliveryMethod fulltext_linktorsrc
Discipline Anatomy & Physiology
EndPage 357
ExternalDocumentID 15312912
10_1016_j_pneurobio_2004_05_005
Genre Research Support, U.S. Gov't, P.H.S
Journal Article
Review
GrantInformation_xml – fundername: NIMH NIH HHS
  grantid: MH60225
GroupedDBID ---
--K
--M
-~X
.GJ
.~1
0R~
123
1B1
1CY
1RT
1~.
1~5
29P
4.4
457
4G.
53G
5RE
5VS
7-5
71M
8P~
9JM
AABNK
AAEDT
AAEDW
AAIKJ
AAKOC
AALRI
AAOAW
AAQFI
AAQXK
AATTM
AAXKI
AAXLA
AAXUO
AAYWO
AAYXX
ABCQJ
ABFNM
ABFRF
ABJNI
ABMAC
ABWVN
ABXDB
ACDAQ
ACGFO
ACGFS
ACIUM
ACRLP
ACRPL
ACVFH
ADBBV
ADCNI
ADEZE
ADIYS
ADMUD
ADNMO
ADVLN
AEBSH
AEFWE
AEIPS
AEKER
AENEX
AEUPX
AFJKZ
AFPUW
AFTJW
AFXIZ
AGCQF
AGHFR
AGQPQ
AGRNS
AGUBO
AGWIK
AGYEJ
AHHHB
AIEXJ
AIGII
AIIUN
AIKHN
AITUG
AKBMS
AKRWK
AKYEP
ALMA_UNASSIGNED_HOLDINGS
AMRAJ
ANKPU
APXCP
ASPBG
AVWKF
AXJTR
AZFZN
BKOJK
BLXMC
BNPGV
C45
CITATION
CS3
DU5
EBS
EFJIC
EJD
EO8
EO9
EP2
EP3
F5P
FDB
FEDTE
FGOYB
FIRID
FNPLU
FYGXN
G-2
G-Q
GBLVA
HMQ
HVGLF
HZ~
IHE
J1W
KOM
L7B
M2V
M41
MO0
MOBAO
N9A
O-L
O9-
OAUVE
OVD
OZT
P-8
P-9
P2P
PC.
Q38
R2-
RIG
ROL
RPZ
SCC
SDF
SDG
SDP
SES
SEW
SNS
SPCBC
SSH
SSN
SSZ
T5K
TEORI
WUQ
ZGI
ZXP
~G-
AACTN
AFKWA
AJOXV
AMFUW
CGR
CUY
CVF
ECM
EIF
NPM
7TK
7X8
ID FETCH-LOGICAL-c406t-f8ac0fe0b45f60dbad78ff3e78db9910ec3e6e63306bd0a71447ef151a7e584a3
ISSN 0301-0082
IngestDate Thu Jul 10 19:00:19 EDT 2025
Fri Jul 11 11:17:43 EDT 2025
Wed Feb 19 01:54:55 EST 2025
Tue Jul 01 02:40:13 EDT 2025
Thu Apr 24 23:04:47 EDT 2025
IsPeerReviewed true
IsScholarly true
Issue 5
Language English
License https://www.elsevier.com/tdm/userlicense/1.0
LinkModel OpenURL
MergedId FETCHMERGED-LOGICAL-c406t-f8ac0fe0b45f60dbad78ff3e78db9910ec3e6e63306bd0a71447ef151a7e584a3
Notes ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
ObjectType-Review-3
content type line 23
ObjectType-Article-1
ObjectType-Feature-2
PMID 15312912
PQID 18036678
PQPubID 23462
PageCount 47
ParticipantIDs proquest_miscellaneous_66794726
proquest_miscellaneous_18036678
pubmed_primary_15312912
crossref_primary_10_1016_j_pneurobio_2004_05_005
crossref_citationtrail_10_1016_j_pneurobio_2004_05_005
ProviderPackageCode CITATION
AAYXX
PublicationCentury 2000
PublicationDate 2004-8-00
2004-Aug
20040801
PublicationDateYYYYMMDD 2004-08-01
PublicationDate_xml – month: 08
  year: 2004
  text: 2004-8-00
PublicationDecade 2000
PublicationPlace England
PublicationPlace_xml – name: England
PublicationTitle Progress in neurobiology
PublicationTitleAlternate Prog Neurobiol
PublicationYear 2004
References Walsh (10.1016/j.pneurobio.2004.05.005_bib337) 2002; 416
Baker (10.1016/j.pneurobio.2004.05.005_bib17) 1987; 15
Hochstrasser (10.1016/j.pneurobio.2004.05.005_bib126) 1998; 12
Valverde (10.1016/j.pneurobio.2004.05.005_bib328) 1971; 33
Sapetschnig (10.1016/j.pneurobio.2004.05.005_bib277) 2002; 21
Kandel (10.1016/j.pneurobio.2004.05.005_bib148) 1979; 73
Ferdous (10.1016/j.pneurobio.2004.05.005_bib82) 2001; 7
Martin (10.1016/j.pneurobio.2004.05.005_bib197) 1997; 91
Helliwell (10.1016/j.pneurobio.2004.05.005_bib119) 2001; 153
Hari (10.1016/j.pneurobio.2004.05.005_bib110) 2001; 15
Murphy (10.1016/j.pneurobio.2004.05.005_bib227) 2000; 20
Carbone (10.1016/j.pneurobio.2004.05.005_bib42) 1997; 57
Plafker (10.1016/j.pneurobio.2004.05.005_bib253) 2000; 19
Rocca (10.1016/j.pneurobio.2004.05.005_bib268) 2001; 12
Tamura (10.1016/j.pneurobio.2004.05.005_bib312) 1998; 95
Traidej (10.1016/j.pneurobio.2004.05.005_bib318) 2000; 10
Burbea (10.1016/j.pneurobio.2004.05.005_bib38) 2002; 35
Barco (10.1016/j.pneurobio.2004.05.005_bib19) 2002; 108
Lynch (10.1016/j.pneurobio.2004.05.005_bib192) 1984; 224
Aravind (10.1016/j.pneurobio.2004.05.005_bib6) 2000; 10
Glickman (10.1016/j.pneurobio.2004.05.005_bib99) 1998; 18
Lam (10.1016/j.pneurobio.2004.05.005_bib167) 1997; 272
10.1016/j.pneurobio.2004.05.005_bib101
Dubiel (10.1016/j.pneurobio.2004.05.005_bib76) 1995; 21
Bozdagi (10.1016/j.pneurobio.2004.05.005_bib35) 2000; 28
Trachtenberg (10.1016/j.pneurobio.2004.05.005_bib317) 2002; 20
Ciechanover (10.1016/j.pneurobio.2004.05.005_bib53) 1991; 88
Ciechanover (10.1016/j.pneurobio.2004.05.005_bib52) 2003; 40
Mendez (10.1016/j.pneurobio.2004.05.005_bib216) 2002; 21
Rotin (10.1016/j.pneurobio.2004.05.005_bib272) 2000; 9
Saigoh (10.1016/j.pneurobio.2004.05.005_bib279) 1999; 23
Buchs (10.1016/j.pneurobio.2004.05.005_bib37) 1996; 93
Hatakeyama (10.1016/j.pneurobio.2004.05.005_bib113) 2001; 276
Saurin (10.1016/j.pneurobio.2004.05.005_bib281) 1996; 21
Crick (10.1016/j.pneurobio.2004.05.005_bib59) 1984; 312
Gieffers (10.1016/j.pneurobio.2004.05.005_bib95) 1999; 96
Pak (10.1016/j.pneurobio.2004.05.005_bib243) 2003; 302
Satoh (10.1016/j.pneurobio.2004.05.005_bib280) 2001; 40
Bedford (10.1016/j.pneurobio.2004.05.005_bib22) 2001; 4
McCracken (10.1016/j.pneurobio.2004.05.005_bib210) 2003; 25
Laroia (10.1016/j.pneurobio.2004.05.005_bib168) 1999; 284
Tyers (10.1016/j.pneurobio.2004.05.005_bib321) 1999; 284
Verma (10.1016/j.pneurobio.2004.05.005_bib334) 2000; 11
Ding (10.1016/j.pneurobio.2004.05.005_bib74) 2002; 277
Lotharius (10.1016/j.pneurobio.2004.05.005_bib189) 2002; 3
Glickman (10.1016/j.pneurobio.2004.05.005_bib97) 2002; 82
Ohi (10.1016/j.pneurobio.2004.05.005_bib237) 2003; 10
Schwarzschild (10.1016/j.pneurobio.2004.05.005_bib287) 1997; 17
Peters (10.1016/j.pneurobio.2004.05.005_bib251) 1996; 274
Hietanen (10.1016/j.pneurobio.2004.05.005_bib123) 2000; 97
Jiang (10.1016/j.pneurobio.2004.05.005_bib144) 2001; 276
Jensen (10.1016/j.pneurobio.2004.05.005_bib141) 1995; 83
Liu (10.1016/j.pneurobio.2004.05.005_bib184) 2003; 959
Schwob (10.1016/j.pneurobio.2004.05.005_bib288) 1994; 79
Aravind (10.1016/j.pneurobio.2004.05.005_bib7) 1998; 7
Biederer (10.1016/j.pneurobio.2004.05.005_bib28) 1997; 278
Hershko (10.1016/j.pneurobio.2004.05.005_bib122) 1998; 67
McDonald (10.1016/j.pneurobio.2004.05.005_bib212) 2000; 290
Middleton (10.1016/j.pneurobio.2004.05.005_bib217) 2002; 22
Honda (10.1016/j.pneurobio.2004.05.005_bib132) 1999; 18
Meiri (10.1016/j.pneurobio.2004.05.005_bib215) 1994; 91
Trompouki (10.1016/j.pneurobio.2004.05.005_bib319) 2003; 424
Rosenthal (10.1016/j.pneurobio.2004.05.005_bib270) 1999; 274
Mastrandrea (10.1016/j.pneurobio.2004.05.005_bib202) 1999; 274
Schuster (10.1016/j.pneurobio.2004.05.005_bib284) 1996; 17
Hoelzl (10.1016/j.pneurobio.2004.05.005_bib128) 2000; 150
Yamano (10.1016/j.pneurobio.2004.05.005_bib354) 1996; 15
Fang (10.1016/j.pneurobio.2004.05.005_bib80) 2000; 275
O’Leary (10.1016/j.pneurobio.2004.05.005_bib239) 1990; 55
Yu (10.1016/j.pneurobio.2004.05.005_bib360) 2001; 276
McCabe (10.1016/j.pneurobio.2004.05.005_bib208) 2004; 41
Zhou (10.1016/j.pneurobio.2004.05.005_bib364) 1998; 2
Madani (10.1016/j.pneurobio.2004.05.005_bib193) 1999; 18
Wood (10.1016/j.pneurobio.2004.05.005_bib351) 2003; 11
Nakazawa (10.1016/j.pneurobio.2004.05.005_bib231) 1999; 73
Rechsteiner (10.1016/j.pneurobio.2004.05.005_bib264) 1993; 268
Martin-Aparicio (10.1016/j.pneurobio.2004.05.005_bib200) 2001; 21
Mayer (10.1016/j.pneurobio.2004.05.005_bib206) 1989; 244
Baker (10.1016/j.pneurobio.2004.05.005_bib18) 1991; 19
Plemper (10.1016/j.pneurobio.2004.05.005_bib257) 1999; 24
Ward (10.1016/j.pneurobio.2004.05.005_bib346) 1995; 83
Mason (10.1016/j.pneurobio.2004.05.005_bib201) 1998; 430
Hofmann (10.1016/j.pneurobio.2004.05.005_bib131) 2001; 26
Lange (10.1016/j.pneurobio.2004.05.005_bib173) 1995; 58
Wilkinson (10.1016/j.pneurobio.2004.05.005_bib344) 1992; 20
Sommer (10.1016/j.pneurobio.2004.05.005_bib299) 1993; 365
Bock (10.1016/j.pneurobio.2004.05.005_bib31) 1999; 11
Qian (10.1016/j.pneurobio.2004.05.005_bib263) 1993; 361
Jackson (10.1016/j.pneurobio.2004.05.005_bib138) 2000; 10
Abrams (10.1016/j.pneurobio.2004.05.005_bib1) 1985; 5
Beer-Romero (10.1016/j.pneurobio.2004.05.005_bib23) 1997; 14
Foroud (10.1016/j.pneurobio.2004.05.005_bib87) 1995; 37
Lahav-Baratz (10.1016/j.pneurobio.2004.05.005_bib166) 1995; 92
Dittmar (10.1016/j.pneurobio.2004.05.005_bib75) 2002; 295
Ehlers (10.1016/j.pneurobio.2004.05.005_bib79) 2003; 6
Pak (10.1016/j.pneurobio.2004.05.005_bib244) 2001; 31
Abriel (10.1016/j.pneurobio.2004.05.005_bib3) 2000; 466
Dash (10.1016/j.pneurobio.2004.05.005_bib61) 1990; 345
Abrams (10.1016/j.pneurobio.2004.05.005_bib2) 1998; 4
Handley (10.1016/j.pneurobio.2004.05.005_bib109) 1991; 88
Bence (10.1016/j.pneurobio.2004.05.005_bib24) 2001; 292
Chain (10.1016/j.pneurobio.2004.05.005_bib45) 1995; 15
Hart (10.1016/j.pneurobio.2004.05.005_bib111) 1999; 9
Mosesson (10.1016/j.pneurobio.2004.05.005_bib225) 2003; 278
Lee (10.1016/j.pneurobio.2004.05.005_bib176) 2003; 85
Yaron (10.1016/j.pneurobio.2004.05.005_bib357) 1998; 396
D’Andrea (10.1016/j.pneurobio.2004.05.005_bib60) 1998; 33
Hegde (10.1016/j.pneurobio.2004.05.005_bib115) 2002; 3
Kotani (10.1016/j.pneurobio.2004.05.005_bib164) 1998; 1
Salghetti (10.1016/j.pneurobio.2004.05.005_bib275) 2000; 97
Yamada (10.1016/j.pneurobio.2004.05.005_bib352) 1997; 110
Pilon (10.1016/j.pneurobio.2004.05.005_bib255) 1997; 16
Myat (10.1016/j.pneurobio.2004.05.005_bib229) 2002; 35
Joazeiro (10.1016/j.pneurobio.2004.05.005_bib146) 2000; 102
von der Lehr (10.1016/j.pneurobio.2004.05.005_bib336) 2003; 11
Tanaka (10.1016/j.pneurobio.2004.05.005_bib313) 2000; 25
Werner (10.1016/j.pneurobio.2004.05.005_bib341) 1996; 93
Lorick (10.1016/j.pneurobio.2004.05.005_bib188) 1999; 96
Gorbea (10.1016/j.pneurobio.2004.05.005_bib102) 2000; 275
Yu (10.1016/j.pneurobio.2004.05.005_bib359) 1998; 279
Hofmann (10.1016/j.pneurobio.2004.05.005_bib130) 1999; 96
Wheeler (10.1016/j.pneurobio.2004.05.005_bib342) 2002; 277
Yao (10.1016/j.pneurobio.2004.05.005_bib356) 1999; 9
Fujita (10.1016/j.pneurobio.2004.05.005_bib91) 2002; 4
Chain (10.1016/j.pneurobio.2004.05.005_bib46) 1999; 22
Groll (10.1016/j.pneurobio.2004.05.005_bib104) 1997; 386
Sassone-Corsi (10.1016/j.pneurobio.2004.05.005_bib278) 1995; 11
Bernier-Villamor (10.1016/j.pneurobio.2004.05.005_bib26) 2002; 108
10.1016/j.pneurobio.2004.05.005_bib29
Bochtler (10.1016/j.pneurobio.2004.05.005_bib30) 1999; 28
Campbell (10.1016/j.pneurobio.2004.05.005_bib41) 2001; 32
Mori (10.1016/j.pneurobio.2004.05.005_bib222) 1992; 267
Denny (10.1016/j.pneurobio.2004.05.005_bib69) 1990; 534
Rodriguez (10.1016/j.pneurobio.2004.05.005_bib269) 2003; 4
Zhang (10.1016/j.pneurobio.2004.05.005_bib362) 2000; 97
Huibregtse (10.1016/j.pneurobio.2004.05.005_bib134) 1993; 13
Richmond (10.1016/j.pneurobio.2004.05.005_bib266) 1997; 272
Puertollano (10.1016/j.pneurobio.2004.05.005_bib262) 2004; 6
Kitada (10.1016/j.pneurobio.2004.05.005_bib161) 1998; 392
Wing (10.1016/j.pneurobio.2004.05.005_bib349) 2003; 35
Oldham (10.1016/j.pneurobio.2004.05.005_bib238) 2002; 12
Lawrence (10.1016/j.pneurobio.2004.05.005_bib175) 1998; 121
Papa (10.1016/j.pneurobio.2004.05.005_bib246) 1995; 15
Onyike (10.1016/j.pneurobio.2004.05.005_bib241) 1998; 71
Wan (10.1016/j.pneurobio.2004.05.005_bib338) 2000; 26
Bailey (10.1016/j.pneurobio.2004.05.005_bib15) 1993; 55
Desmond (10.1016/j.pneurobio.2004.05.005_bib71) 1986; 253
Watts (10.1016/j.pneurobio.2004.05.005_bib340) 2003; 38
Bailey (10.1016/j.pneurobio.2004.05.005_bib13) 1991; 627
Casadio (10.1016/j.pneurobio.2004.05.005_bib43) 1999; 99
Confalonieri (10.1016/j.pneurobio.2004.05.005_bib55) 2000; 150
Globus (10.1016/j.pneurobio.2004.05.005_bib100) 1967; 19
Kawahara (10.1016/j.pneurobio.2004.05.005_bib154) 1994; 166
Calabresi (10.1016/j.pneurobio.2004.05.005_bib40) 2000; 12
Leggett (10.1016/j.pneurobio.2004.05.005_bib171) 2002; 10
Polo (10.1016/j.pneurobio.2004.05.005_bib258) 2002; 416
Frey (10.1016/j.pneurobio.2004.05.005_bib89) 1998; 37
Kornitzer (10.1016/j.pneurobio.2004.05.005_bib163) 2000; 182
Luscher (10.1016/j.pneurobio.2004.05.005_bib191) 2001; 3
Hegde (10.1016/j.pneurobio.2004.05.005_bib116) 1993; 90
Dubnau (10.1016/j.pneurobio.2004.05.005_bib77) 2003; 13
Mizushima (10.1016/j.pneurobio.2004.05.005_bib219) 1998; 395
Swaminathan (10.1016/j.pneurobio.2004.05.005_bib309) 1999; 10
Salghetti (10.1016/j.pneurobio.2004.05.005_bib276) 2001; 293
Van Leeuwen (10.1016/j.pneurobio.2004.05.005_bib331) 1998; 279
Hauser (10.1016/j.pneurobio.2004.05.005_bib114) 1998; 141
Verma (10.1016/j.pneurobio.2004.05.005_bib332) 1997; 278
Frey (10.1016/j.pneurobio.2004.05.005_bib88) 1998; 21
Marmor (10.1016/j.pneurobio.2004.05.005_bib196) 2004; 23
Pomerantz (10.1016/j.pneurobio.2004.05.005_bib260) 1998; 92
Terrell (10.1016/j.pneurobio.2004.05.005_bib314) 1998; 1
Brummelkamp (10.1016/j.pneurobio.2004.05.005_bib36) 2003; 424
Hegde (10.1016/j.pneurobio.2004.05.005_bib117) 1997; 89
Fu (10.1016/j.pneurobio.2004.05.005_bib90) 2001; 20
Yang (10.1016/j.pneurobio.2004.05.005_bib355) 1995; 270
Finley (10.1016/j.pneurobio.2004.05.005_bib83) 1991; 7
Takayanagi (10.1016/j.pneurobio.2004.05.005_bib311) 1996; 228
Jenuwein (10.1016/j.p
References_xml – volume: 83
  start-page: 121
  year: 1995
  ident: 10.1016/j.pneurobio.2004.05.005_bib346
  article-title: Degradation of CFTR by the ubiquitin-proteasome pathway
  publication-title: Cell
  doi: 10.1016/0092-8674(95)90240-6
– volume: 329
  start-page: 62
  year: 1987
  ident: 10.1016/j.pneurobio.2004.05.005_bib103
  article-title: A molecular mechanism for long-term sensitization in Aplysia
  publication-title: Nature
  doi: 10.1038/329062a0
– volume: 22
  start-page: 6946
  year: 2002
  ident: 10.1016/j.pneurobio.2004.05.005_bib147
  article-title: Rsp5p, a new link between the actin cytoskeleton and endocytosis in the yeast Saccharomyces cerevisiae
  publication-title: Mol. Cell. Biol.
  doi: 10.1128/MCB.22.20.6946-6958.2002
– volume: 274
  start-page: 33959
  year: 1999
  ident: 10.1016/j.pneurobio.2004.05.005_bib270
  article-title: The epsins define a family of proteins that interact with components of the clathrin coat and contain a new protein module
  publication-title: J. Biol. Chem.
  doi: 10.1074/jbc.274.48.33959
– volume: 5
  start-page: 239
  year: 2002
  ident: 10.1016/j.pneurobio.2004.05.005_bib305
  article-title: Rapid turnover of actin in dendritic spines and its regulation by activity
  publication-title: Nat. Neurosci.
  doi: 10.1038/nn811
– volume: 12
  start-page: 2587
  year: 2003
  ident: 10.1016/j.pneurobio.2004.05.005_bib136
  article-title: The autosomal recessive juvenile Parkinson disease gene product, parkin, interacts with and ubiquitinates synaptotagmin XI
  publication-title: Hum. Mol. Genet.
  doi: 10.1093/hmg/ddg269
– volume: 959
  start-page: 68
  year: 2003
  ident: 10.1016/j.pneurobio.2004.05.005_bib184
  article-title: The cytoplasmic polyadenylation element binding protein and polyadenylation of messenger RNA in Aplysia neurons
  publication-title: Brain Res.
  doi: 10.1016/S0006-8993(02)03729-0
– volume: 302
  start-page: 1368
  year: 2003
  ident: 10.1016/j.pneurobio.2004.05.005_bib243
  article-title: Targeted protein degradation and synapse remodeling by an inducible protein kinase
  publication-title: Science
  doi: 10.1126/science.1082475
– volume: 24
  start-page: 266
  year: 1999
  ident: 10.1016/j.pneurobio.2004.05.005_bib257
  article-title: Retrograde protein translocation: ERADication of secretory proteins in health and disease
  publication-title: Trends Biochem. Sci.
  doi: 10.1016/S0968-0004(99)01420-6
– volume: 119
  start-page: 1633
  issue: Pt. 5
  year: 1996
  ident: 10.1016/j.pneurobio.2004.05.005_bib174
  article-title: Executive and mnemonic functions in early Huntington’s disease
  publication-title: Brain
  doi: 10.1093/brain/119.5.1633
– volume: 1
  start-page: 193
  year: 1998
  ident: 10.1016/j.pneurobio.2004.05.005_bib314
  article-title: A function for monoubiquitination in the internalization of a G protein-coupled receptor
  publication-title: Mol. Cell
  doi: 10.1016/S1097-2765(00)80020-9
– volume: 4
  start-page: 496
  year: 1998
  ident: 10.1016/j.pneurobio.2004.05.005_bib2
  article-title: Analysis of sequence-dependent interactions between transient calcium and transmitter stimuli in activating adenylyl cyclase in Aplysia: possible contribution to CS–US sequence requirement during conditioning
  publication-title: Learn. Mem.
  doi: 10.1101/lm.4.6.496
– volume: 11
  start-page: 2566
  year: 1999
  ident: 10.1016/j.pneurobio.2004.05.005_bib31
  article-title: Filial imprinting in domestic chicks is associated with spine pruning in the associative area, dorsocaudal neostriatum
  publication-title: Eur. J. Neurosci.
  doi: 10.1046/j.1460-9568.1999.00713.x
– volume: 100
  start-page: 13680
  year: 2003
  ident: 10.1016/j.pneurobio.2004.05.005_bib96
  article-title: Axonal transport of eukaryotic translation elongation factor 1alpha mRNA couples transcription in the nucleus to long-term facilitation at the synapse
  publication-title: Proc. Natl. Acad. Sci. U.S.A.
  doi: 10.1073/pnas.1835674100
– volume: 13
  start-page: 887
  year: 2003
  ident: 10.1016/j.pneurobio.2004.05.005_bib363
  article-title: The ubiquitin proteasome system functions as an inhibitory constraint on synaptic strengthening
  publication-title: Curr. Biol.
  doi: 10.1016/S0960-9822(03)00332-4
– volume: 121
  start-page: 1329
  issue: Pt. 7
  year: 1998
  ident: 10.1016/j.pneurobio.2004.05.005_bib175
  article-title: Evidence for specific cognitive deficits in preclinical Huntington’s disease
  publication-title: Brain
  doi: 10.1093/brain/121.7.1329
– volume: 294
  start-page: 1307
  year: 2001
  ident: 10.1016/j.pneurobio.2004.05.005_bib293
  article-title: Regulation of receptor fate by ubiquitination of activated beta 2-adrenergic receptor and beta-arrestin
  publication-title: Science
  doi: 10.1126/science.1063866
– volume: 38
  start-page: 447
  year: 2003
  ident: 10.1016/j.pneurobio.2004.05.005_bib92
  article-title: Hippocampal LTP is accompanied by enhanced F-actin content within the dendritic spine that is essential for late LTP maintenance in vivo
  publication-title: Neuron
  doi: 10.1016/S0896-6273(03)00206-X
– volume: 294
  start-page: 1030
  year: 2001
  ident: 10.1016/j.pneurobio.2004.05.005_bib149
  article-title: The molecular biology of memory storage: a dialogue between genes and synapses
  publication-title: Science
  doi: 10.1126/science.1067020
– volume: 19
  start-page: 4314
  year: 1999
  ident: 10.1016/j.pneurobio.2004.05.005_bib158
  article-title: A role of actin filament in synaptic transmission and long-term potentiation
  publication-title: J. Neurosci.
  doi: 10.1523/JNEUROSCI.19-11-04314.1999
– volume: 278
  start-page: 14498
  year: 2003
  ident: 10.1016/j.pneurobio.2004.05.005_bib292
  article-title: Trafficking patterns of beta-arrestin and G protein-coupled receptors determined by the kinetics of beta-arrestin deubiquitination
  publication-title: J. Biol. Chem.
  doi: 10.1074/jbc.M209626200
– volume: 3
  start-page: 271
  year: 2002
  ident: 10.1016/j.pneurobio.2004.05.005_bib10
  article-title: ESCRT-III: an endosome-associated heterooligomeric protein complex required for mvb sorting
  publication-title: Dev. Cell
  doi: 10.1016/S1534-5807(02)00220-4
– volume: 276
  start-page: 20357
  year: 2001
  ident: 10.1016/j.pneurobio.2004.05.005_bib183
  article-title: Divergent N-terminal sequences of a deubiquitinating enzyme modulate substrate specificity
  publication-title: J. Biol. Chem.
  doi: 10.1074/jbc.M008761200
– volume: 457
  start-page: 333
  year: 1999
  ident: 10.1016/j.pneurobio.2004.05.005_bib361
  article-title: The proteasome inhibitor PI31 competes with PA28 for binding to 20S proteasomes
  publication-title: FEBS Lett.
  doi: 10.1016/S0014-5793(99)01072-8
– volume: 11
  start-page: 141
  year: 2000
  ident: 10.1016/j.pneurobio.2004.05.005_bib343
  article-title: Ubiquitination and deubiquitination: targeting of proteins for degradation by the proteasome
  publication-title: Semin. Cell Dev. Biol.
  doi: 10.1006/scdb.2000.0164
– volume: 273
  start-page: 9734
  year: 1998
  ident: 10.1016/j.pneurobio.2004.05.005_bib72
  article-title: Ubiquitination is required for the retro-translocation of a short-lived luminal endoplasmic reticulum glycoprotein to the cytosol for degradation by the proteasome
  publication-title: J. Biol. Chem.
  doi: 10.1074/jbc.273.16.9734
– volume: 6
  start-page: 679
  year: 1991
  ident: 10.1016/j.pneurobio.2004.05.005_bib282
  article-title: Target-dependent structural changes in sensory neurons of Aplysia accompany long-term heterosynaptic inhibition
  publication-title: Neuron
  doi: 10.1016/0896-6273(91)90166-W
– volume: 365
  start-page: 176
  year: 1993
  ident: 10.1016/j.pneurobio.2004.05.005_bib299
  article-title: A protein translocation defect linked to ubiquitin conjugation at the endoplasmic reticulum
  publication-title: Nature
  doi: 10.1038/365176a0
– volume: 279
  start-page: 242
  year: 1998
  ident: 10.1016/j.pneurobio.2004.05.005_bib331
  article-title: Frameshift mutants of β-amyloid precursor protein and ubiquitin-B in Alzheimer’s and Down’s patients
  publication-title: Science
  doi: 10.1126/science.279.5348.242
– volume: 41
  start-page: 891
  year: 2004
  ident: 10.1016/j.pneurobio.2004.05.005_bib208
  article-title: Highwire regulates presynaptic BMP signaling essential for synaptic growth
  publication-title: Neuron
  doi: 10.1016/S0896-6273(04)00073-X
– volume: 55
  start-page: 453
  year: 1990
  ident: 10.1016/j.pneurobio.2004.05.005_bib239
  article-title: Target selection by cortical axons: alternative mechanisms to establish axonal connections in the developing brain
  publication-title: Cold Spring Harb. Symp. Quant. Biol.
  doi: 10.1101/SQB.1990.055.01.045
– volume: 57
  start-page: 5498
  year: 1997
  ident: 10.1016/j.pneurobio.2004.05.005_bib42
  article-title: eps15 and eps15R are essential components of the endocytic pathway
  publication-title: Cancer Res.
– volume: 275
  start-page: 875
  year: 2000
  ident: 10.1016/j.pneurobio.2004.05.005_bib102
  article-title: Mapping subunit contacts in the regulatory complex of the 26 S proteasome. S2 and S5b form a tetramer with ATPase subunits S4 and S7
  publication-title: J. Biol. Chem.
  doi: 10.1074/jbc.275.2.875
– volume: 18
  start-page: 5528
  year: 1999
  ident: 10.1016/j.pneurobio.2004.05.005_bib152
  article-title: The polo-like protein kinases Fnk and Snk associate with a Ca(2+)- and integrin-binding protein and are regulated dynamically with synaptic plasticity
  publication-title: EMBO J.
  doi: 10.1093/emboj/18.20.5528
– volume: 275
  start-page: 40765
  year: 2000
  ident: 10.1016/j.pneurobio.2004.05.005_bib186
  article-title: Identification and characterization of a SUMO-1 conjugation system that modifies neuronal calcium/calmodulin-dependent protein kinase II in Drosophila melanogaster
  publication-title: J. Biol. Chem.
  doi: 10.1074/jbc.M003949200
– volume: 277
  start-page: 11709
  year: 2002
  ident: 10.1016/j.pneurobio.2004.05.005_bib94
  article-title: A principal role for the proteasome in endoplasmic reticulum-associated degradation of misfolded intracellular cystic fibrosis transmembrane conductance regulator
  publication-title: J. Biol. Chem.
  doi: 10.1074/jbc.M111958200
– volume: 272
  start-page: 28438
  year: 1997
  ident: 10.1016/j.pneurobio.2004.05.005_bib167
  article-title: Specificity of the ubiquitin isopeptidase in the PA700 regulatory complex of 26 S proteasomes
  publication-title: J. Biol. Chem.
  doi: 10.1074/jbc.272.45.28438
– volume: 99
  start-page: 221
  year: 1999
  ident: 10.1016/j.pneurobio.2004.05.005_bib43
  article-title: A transient, neuron-wide form of CREB-mediated long-term facilitation can be stabilized at specific synapses by local protein synthesis
  publication-title: Cell
  doi: 10.1016/S0092-8674(00)81653-0
– volume: 4
  start-page: 566
  year: 2003
  ident: 10.1016/j.pneurobio.2004.05.005_bib269
  article-title: The HECT ubiquitin ligase Rsp5p is required for proper nuclear export of mRNA in Saccharomyces cerevisiae
  publication-title: Traffic
  doi: 10.1034/j.1600-0854.2003.00115.x
– volume: 23
  start-page: 3363
  year: 2003
  ident: 10.1016/j.pneurobio.2004.05.005_bib333
  article-title: The Grb10/Nedd4 complex regulates ligand-induced ubiquitination and stability of the insulin-like growth factor I receptor
  publication-title: Mol. Cell. Biol.
  doi: 10.1128/MCB.23.9.3363-3372.2003
– volume: 3
  start-page: 24
  year: 2001
  ident: 10.1016/j.pneurobio.2004.05.005_bib21
  article-title: Hrd1p/Der3p is a membrane-anchored ubiquitin ligase required for ER-associated degradation
  publication-title: Nature Cell Biol.
  doi: 10.1038/35050524
– volume: 37
  start-page: 657
  year: 1995
  ident: 10.1016/j.pneurobio.2004.05.005_bib87
  article-title: Cognitive scores in carriers of Huntington’s disease gene compared to noncarriers
  publication-title: Ann. Neurol.
  doi: 10.1002/ana.410370516
– volume: 51
  start-page: 1
  year: 1995
  ident: 10.1016/j.pneurobio.2004.05.005_bib106
  article-title: cAMP-dependent regulation of gene transcription by cAMP response element-binding protein and cAMP response element modulator
  publication-title: Vitamins Hormones
  doi: 10.1016/S0083-6729(08)61037-7
– volume: 108
  start-page: 109
  year: 2002
  ident: 10.1016/j.pneurobio.2004.05.005_bib252
  article-title: The nucleoporin RanBP2 has SUMO1 E3 ligase activity
  publication-title: Cell
  doi: 10.1016/S0092-8674(01)00633-X
– volume: 10
  start-page: 250
  year: 2003
  ident: 10.1016/j.pneurobio.2004.05.005_bib237
  article-title: Structural insights into the U-box, a domain associated with multi-ubiquitination
  publication-title: Nat. Struct. Biol.
  doi: 10.1038/nsb906
– volume: 93
  start-page: 13797
  year: 1996
  ident: 10.1016/j.pneurobio.2004.05.005_bib341
  article-title: Proteasome-dependent endoplasmic reticulum-associated protein degradation: an unconventional route to a familiar fate
  publication-title: Proc. Natl. Acad. Sci. U.S.A.
  doi: 10.1073/pnas.93.24.13797
– volume: 991
  start-page: 10
  year: 1993
  ident: 10.1016/j.pneurobio.2004.05.005_bib240
  article-title: Development of projection neuron types, axon pathways, and patterned connections of the mammalian cortex
  publication-title: Neuron
– volume: 7
  start-page: 25
  year: 1991
  ident: 10.1016/j.pneurobio.2004.05.005_bib83
  article-title: Ubiquitination
  publication-title: Annu. Rev. Cell Biol.
  doi: 10.1146/annurev.cb.07.110191.000325
– volume: 31
  start-page: 805
  year: 1999
  ident: 10.1016/j.pneurobio.2004.05.005_bib274
  article-title: Epidermal growth factor pathway substrate 15, Eps15
  publication-title: Int. J. Biochem. Cell Biol.
  doi: 10.1016/S1357-2725(99)00042-4
– volume: 25
  start-page: 93
  year: 2000
  ident: 10.1016/j.pneurobio.2004.05.005_bib313
  article-title: Molecular modification of N-cadherin in response to synaptic activity
  publication-title: Neuron
  doi: 10.1016/S0896-6273(00)80874-0
– volume: 23
  start-page: 2057
  year: 2004
  ident: 10.1016/j.pneurobio.2004.05.005_bib196
  article-title: Role of protein ubiquitylation in regulating endocytosis of receptor tyrosine kinases
  publication-title: Oncogene
  doi: 10.1038/sj.onc.1207390
– volume: 416
  start-page: 183
  year: 2002
  ident: 10.1016/j.pneurobio.2004.05.005_bib301
  article-title: Cbl-CIN85-endophilin complex mediates ligand-induced downregulation of EGF receptors
  publication-title: Nature
  doi: 10.1038/416183a
– volume: 85
  start-page: 160
  year: 2003
  ident: 10.1016/j.pneurobio.2004.05.005_bib176
  article-title: Aggregate formation and the impairment of long-term synaptic facilitation by ectopic expression of mutant huntingtin in Aplysia neurons
  publication-title: J. Neurochem.
  doi: 10.1046/j.1471-4159.2003.01650.x
– volume: 272
  start-page: 9002
  year: 1997
  ident: 10.1016/j.pneurobio.2004.05.005_bib25
  article-title: Ubiquitin-dependent degradation of certain protein substrates in vitro requires the molecular chaperone Hsc70
  publication-title: J. Biol. Chem.
  doi: 10.1074/jbc.272.14.9002
– volume: 283
  start-page: 1923
  year: 1999
  ident: 10.1016/j.pneurobio.2004.05.005_bib194
  article-title: Rapid dendritic morphogenesis in CA1 hippocampal dendrites induced by synaptic activity
  publication-title: Science
  doi: 10.1126/science.283.5409.1923
– volume: 11
  start-page: 2433
  year: 1992
  ident: 10.1016/j.pneurobio.2004.05.005_bib234
  article-title: The “second-codon rule” and autophosphorylation govern the stability and activity of Mos during the meiotic cell cycle in Xenopus oocytes
  publication-title: EMBO J.
  doi: 10.1002/j.1460-2075.1992.tb05308.x
– volume: 108
  start-page: 689
  year: 2002
  ident: 10.1016/j.pneurobio.2004.05.005_bib19
  article-title: Expression of constitutively active CREB protein facilitates the late phase of long-term potentiation by enhancing synaptic capture
  publication-title: Cell
  doi: 10.1016/S0092-8674(02)00657-8
– volume: 103
  start-page: 351
  year: 2000
  ident: 10.1016/j.pneurobio.2004.05.005_bib68
  article-title: Activation of the IκB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain
  publication-title: Cell
  doi: 10.1016/S0092-8674(00)00126-4
– volume: 10
  start-page: 429
  year: 2000
  ident: 10.1016/j.pneurobio.2004.05.005_bib138
  article-title: The lore of the RINGS: substrate recognition and catalysis by ubiquitin ligases
  publication-title: Trends Cell Biol.
  doi: 10.1016/S0962-8924(00)01834-1
– volume: 15
  start-page: 1334
  year: 2001
  ident: 10.1016/j.pneurobio.2004.05.005_bib110
  article-title: The Drosophila Su(var)2-10 locus regulates chromosome structure and function and encodes a member of the PIAS protein family
  publication-title: Genes Dev.
  doi: 10.1101/gad.877901
– volume: 67
  start-page: 425
  year: 1998
  ident: 10.1016/j.pneurobio.2004.05.005_bib122
  article-title: The ubiquitin-proteasome pathway
  publication-title: Annu. Rev. Biochem.
  doi: 10.1146/annurev.biochem.67.1.425
– volume: 11
  start-page: 355
  year: 1995
  ident: 10.1016/j.pneurobio.2004.05.005_bib278
  article-title: Transcription factors responsive to cAMP
  publication-title: Annu. Rev. Cell Dev. Biol.
  doi: 10.1146/annurev.cb.11.110195.002035
– volume: 92
  start-page: 9303
  year: 1995
  ident: 10.1016/j.pneurobio.2004.05.005_bib166
  article-title: Reversible phosphorylation controls the activity of cyclosome-associated cyclin-ubiquitin ligase
  publication-title: Proc. Natl. Acad. Sci. U.S.A.
  doi: 10.1073/pnas.92.20.9303
– volume: 8
  start-page: 231
  year: 1998
  ident: 10.1016/j.pneurobio.2004.05.005_bib181
  article-title: Cdc20 is essential for the cyclosome-mediated proteolysis of both Pds1 and Clb2 during M phase in budding yeast
  publication-title: Curr. Biol.
  doi: 10.1016/S0960-9822(98)70088-0
– volume: 26
  start-page: 313
  year: 2000
  ident: 10.1016/j.pneurobio.2004.05.005_bib338
  article-title: Highwire regulates synaptic growth in Drosophila
  publication-title: Nature
– volume: 4
  start-page: 908
  year: 2001
  ident: 10.1016/j.pneurobio.2004.05.005_bib22
  article-title: GABA(A) receptor cell surface number and subunit stability are regulated by the ubiquitin-like protein Plic-1
  publication-title: Nat. Neurosci.
  doi: 10.1038/nn0901-908
– volume: 9
  start-page: 105
  year: 1999
  ident: 10.1016/j.pneurobio.2004.05.005_bib283
  article-title: Neurotrophin regulation of synaptic transmission
  publication-title: Curr. Opin. Neurobiol.
  doi: 10.1016/S0959-4388(99)80013-0
– volume: 116
  start-page: 13
  year: 2003
  ident: 10.1016/j.pneurobio.2004.05.005_bib78
  article-title: Serotonin persistently activates the extracellular signal-related kinase in sensory neurons of Aplysia independently of cAMP or protein kinase C
  publication-title: Neuroscience
  doi: 10.1016/S0306-4522(02)00566-3
– volume: 22
  start-page: 1
  year: 1999
  ident: 10.1016/j.pneurobio.2004.05.005_bib46
  article-title: Mechanisms for generating the autonomous cAMP-dependent protein kinase required for long-term facilitation in Aplysia
  publication-title: Neuron
  doi: 10.1016/S0896-6273(00)80686-8
– volume: 330
  start-page: 683
  year: 1998
  ident: 10.1016/j.pneurobio.2004.05.005_bib230
  article-title: Ubiquitin-like polypeptide conjugates to acceptor proteins in concanavalin A- and interferon gamma-stimulated T-cells
  publication-title: Biochem. J.
  doi: 10.1042/bj3300683
– volume: 20
  start-page: 631
  year: 1992
  ident: 10.1016/j.pneurobio.2004.05.005_bib344
  article-title: Comparisons of neuronal (PGP 9.5) and non-neuronal ubiquitin C-terminal hydrolases
  publication-title: Biochem. Soc. Trans.
  doi: 10.1042/bst0200631
– volume: 14
  start-page: 595
  year: 1997
  ident: 10.1016/j.pneurobio.2004.05.005_bib23
  article-title: Antisense targeting of E6AP elevates p53 in HPV-infected cells but not in normal cells
  publication-title: Oncogene
  doi: 10.1038/sj.onc.1200872
– volume: 3
  start-page: 110
  year: 2002
  ident: 10.1016/j.pneurobio.2004.05.005_bib50
  article-title: Ubiquitin-independent entry into the yeast recycling pathway
  publication-title: Traffic
  doi: 10.1034/j.1600-0854.2002.030204.x
– volume: 386
  start-page: 463
  year: 1997
  ident: 10.1016/j.pneurobio.2004.05.005_bib104
  article-title: Structure of 20S proteasome from yeast at a 2.4 Angstrom resolution
  publication-title: Nature
  doi: 10.1038/386463a0
– volume: 16
  start-page: 713
  year: 2002
  ident: 10.1016/j.pneurobio.2004.05.005_bib44
  article-title: Tissue plasminogen activator is required for corticostriatal long-term potentiation
  publication-title: Eur. J. Neurosci.
  doi: 10.1046/j.1460-9568.2002.02106.x
– volume: 4
  start-page: 222
  year: 2002
  ident: 10.1016/j.pneurobio.2004.05.005_bib91
  article-title: Hakai, a c-Cbl-like protein, ubiquitinates and induces endocytosis of the E-cadherin complex
  publication-title: Nat. Cell Biol.
  doi: 10.1038/ncb758
– volume: 21
  start-page: 5206
  year: 2002
  ident: 10.1016/j.pneurobio.2004.05.005_bib277
  article-title: Transcription factor Sp3 is silenced through SUMO modification by PIAS1
  publication-title: EMBO J.
  doi: 10.1093/emboj/cdf510
– volume: 19
  start-page: 1035
  year: 1991
  ident: 10.1016/j.pneurobio.2004.05.005_bib18
  article-title: The human ubiquitin-52 amino acid fusion protein gene shares several structural features with mammalian ribosomal protein genes
  publication-title: Nucleic Acids Res.
  doi: 10.1093/nar/19.5.1035
– volume: 366
  start-page: 313
  year: 1993
  ident: 10.1016/j.pneurobio.2004.05.005_bib245
  article-title: The yeast DOA4 gene encodes a deubiquitinating enzyme related to a product of the tre-2 oncogene
  publication-title: Nature
  doi: 10.1038/366313a0
– volume: 37
  start-page: 7
  year: 2003
  ident: 10.1016/j.pneurobio.2004.05.005_bib56
  article-title: Pathways to Parkinsonism
  publication-title: Neuron
  doi: 10.1016/S0896-6273(02)01166-2
– volume: 7
  start-page: 981
  year: 2001
  ident: 10.1016/j.pneurobio.2004.05.005_bib82
  article-title: The 19S regulatory particle of the proteasome is required for efficient transcription elongation by RNA polymerase II
  publication-title: Mol. Cell
  doi: 10.1016/S1097-2765(01)00250-7
– volume: 420
  start-page: 812
  year: 2002
  ident: 10.1016/j.pneurobio.2004.05.005_bib105
  article-title: Long-term dendritic spine stability in the adult cortex
  publication-title: Nature
  doi: 10.1038/nature01276
– volume: 96
  start-page: 9124
  year: 1999
  ident: 10.1016/j.pneurobio.2004.05.005_bib93
  article-title: Ubiquitin-dependent degradation of multiple F-box proteins by an autocatalytic mechanism
  publication-title: Proc. Natl. Acad. Sci. U.S.A.
  doi: 10.1073/pnas.96.16.9124
– volume: 293
  start-page: 263
  year: 2001
  ident: 10.1016/j.pneurobio.2004.05.005_bib296
  article-title: Ubiquitination of a new form of alpha-synuclein by parkin from human brain: implications for Parkinson’s disease
  publication-title: Science
  doi: 10.1126/science.1060627
– volume: 20
  start-page: 7052
  year: 2001
  ident: 10.1016/j.pneurobio.2004.05.005_bib65
  article-title: Phosphorylation of Nedd4-2 by Sgk1 regulates epithelial Na+ channel cell surface expression
  publication-title: EMBO J.
  doi: 10.1093/emboj/20.24.7052
– volume: 295
  start-page: 2442
  year: 2002
  ident: 10.1016/j.pneurobio.2004.05.005_bib75
  article-title: Role of a ubiquitin-like modification in polarized morphogenesis
  publication-title: Science
  doi: 10.1126/science.1069989
– volume: 22
  start-page: 2718
  year: 2002
  ident: 10.1016/j.pneurobio.2004.05.005_bib217
  article-title: Gene expression profiling reveals alterations of specific metabolic pathways in schizophrenia
  publication-title: J. Neurosci.
  doi: 10.1523/JNEUROSCI.22-07-02718.2002
– volume: 278
  start-page: 15429
  year: 2003
  ident: 10.1016/j.pneurobio.2004.05.005_bib294
  article-title: Tumor necrosis factor (TNF)-induced germinal center kinase-related (GCKR) and stress-activated protein kinase (SAPK) activation depends upon the E2/E3 complex Ubc13-Uev1A/TNF receptor-associated factor 2 (TRAF2)
  publication-title: J. Biol. Chem.
  doi: 10.1074/jbc.M211796200
– volume: 2
  start-page: 745
  year: 2002
  ident: 10.1016/j.pneurobio.2004.05.005_bib298
  article-title: Regulated SUMOylation and ubiquitination of DdMEK1 is required for proper chemotaxis
  publication-title: Dev. Cell
  doi: 10.1016/S1534-5807(02)00186-7
– volume: 40
  start-page: 427
  year: 2003
  ident: 10.1016/j.pneurobio.2004.05.005_bib52
  article-title: The ubiquitin proteasome system in neurodegenerative diseases. Sometimes the chicken, sometimes the egg
  publication-title: Neuron
  doi: 10.1016/S0896-6273(03)00606-8
– volume: 298
  start-page: 789
  year: 2002
  ident: 10.1016/j.pneurobio.2004.05.005_bib290
  article-title: Alzheimer’s disease is a synaptic failure
  publication-title: Science
  doi: 10.1126/science.1074069
– ident: 10.1016/j.pneurobio.2004.05.005_bib323
– volume: 279
  start-page: 1219
  year: 1998
  ident: 10.1016/j.pneurobio.2004.05.005_bib359
  article-title: Identification of a cullin homology region in a subunit of the anaphase-promoting complex
  publication-title: Science
  doi: 10.1126/science.279.5354.1219
– volume: 20
  start-page: 6568
  year: 2000
  ident: 10.1016/j.pneurobio.2004.05.005_bib182
  article-title: Divergent N-terminal sequences target an inducible testis deubiquitinating enzyme to distinct subcellular structures
  publication-title: Mol. Cell. Biol.
  doi: 10.1128/MCB.20.17.6568-6578.2000
– volume: 17
  start-page: 3455
  year: 1997
  ident: 10.1016/j.pneurobio.2004.05.005_bib287
  article-title: Glutamate, but not dopamine, stimulates stress-activated protein kinase and AP-1-mediated transcription in striatal neurons
  publication-title: J. Neurosci.
  doi: 10.1523/JNEUROSCI.17-10-03455.1997
– volume: 91
  start-page: 3196
  year: 1994
  ident: 10.1016/j.pneurobio.2004.05.005_bib215
  article-title: Overexpression of urokinase-type plasminogen activator in transgenic mice is correlated with impaired learning
  publication-title: Proc. Natl. Acad. Sci. U.S.A.
  doi: 10.1073/pnas.91.8.3196
– volume: 9–10
  start-page: 981
  year: 2000
  ident: 10.1016/j.pneurobio.2004.05.005_bib5
  article-title: Analysis of the deubiquitinating enzymes of the yeast S. cerevisiae
  publication-title: Biol. Chem.
  doi: 10.1515/BC.2000.121
– volume: 20
  start-page: 788
  year: 2002
  ident: 10.1016/j.pneurobio.2004.05.005_bib317
  article-title: Long-term in vivo imaging of experience-dependent synaptic plasticity in adult cortex
  publication-title: Nature
  doi: 10.1038/nature01273
– volume: 11
  start-page: 3425
  year: 2000
  ident: 10.1016/j.pneurobio.2004.05.005_bib334
  article-title: Proteasomal proteomics: identification of nucleotide-sensitive proteasome-interacting proteins by mass spectrometric analysis of affinity-purified proteasomes
  publication-title: Mol. Biol. Cell
  doi: 10.1091/mbc.11.10.3425
– volume: 166
  start-page: 623
  year: 1994
  ident: 10.1016/j.pneurobio.2004.05.005_bib154
  article-title: Intra cellular calcium mobilization regulates the activity of 26 S proteasome during the metaphase-anaphase transition in the ascidian meiotic cell cycle
  publication-title: Dev. Biol.
  doi: 10.1006/dbio.1994.1342
– volume: 21
  start-page: 382
  year: 2001
  ident: 10.1016/j.pneurobio.2004.05.005_bib157
  article-title: Serotonin activates S6 kinase in a rapamycin-sensitive manner in Aplysia synaptosomes
  publication-title: J. Neurosci.
  doi: 10.1523/JNEUROSCI.21-02-00382.2001
– volume: 18
  start-page: 22
  year: 1999
  ident: 10.1016/j.pneurobio.2004.05.005_bib132
  article-title: Association of p19(ARF) with Mdm2 inhibits ubiquitin ligase activity of Mdm2 for tumor suppressor p53
  publication-title: EMBO J.
  doi: 10.1093/emboj/18.1.22
– volume: 98
  start-page: 1218
  year: 2001
  ident: 10.1016/j.pneurobio.2004.05.005_bib120
  article-title: Complete switch from Mdm2 to human papillomavirus E6-mediated degradation of p53 in cervical cancer cells
  publication-title: Proc. Natl. Acad. Sci. U.S.A.
  doi: 10.1073/pnas.031470698
– volume: 3
  start-page: 283
  year: 2002
  ident: 10.1016/j.pneurobio.2004.05.005_bib9
  article-title: Endosome-associated complex, ESCRT-II, recruits transport machinery for protein sorting at the multivesicular body
  publication-title: Dev. Cell
  doi: 10.1016/S1534-5807(02)00219-8
– volume: 277
  start-page: 49554
  year: 2002
  ident: 10.1016/j.pneurobio.2004.05.005_bib303
  article-title: A lack of SUMO conjugation affects cNLS-dependent nuclear protein import in yeast
  publication-title: J. Biol. Chem.
  doi: 10.1074/jbc.M207991200
– volume: 23
  start-page: 204
  year: 1998
  ident: 10.1016/j.pneurobio.2004.05.005_bib129
  article-title: The PCI domain: a common theme in three multi-protein complexes
  publication-title: Trends Biochem. Sci.
  doi: 10.1016/S0968-0004(98)01217-1
– volume: 20
  start-page: 157
  year: 1997
  ident: 10.1016/j.pneurobio.2004.05.005_bib47
  article-title: Molecular genetic analysis of synaptic plasticity, activity-dependent neural development, learning, and memory in the mammalian brain
  publication-title: Annu. Rev. Neurosci.
  doi: 10.1146/annurev.neuro.20.1.157
– volume: 27
  start-page: 506
  year: 2002
  ident: 10.1016/j.pneurobio.2004.05.005_bib143
  article-title: Regulation and function of local protein synthesis in neuronal dendrites
  publication-title: Trends Biochem. Sci.
  doi: 10.1016/S0968-0004(02)02190-4
– volume: 11
  start-page: 253
  year: 1993
  ident: 10.1016/j.pneurobio.2004.05.005_bib226
  article-title: The Drosophila bendless gene encodes a neural protein related to ubiquitin-conjugating enzymes
  publication-title: Neuron
  doi: 10.1016/0896-6273(93)90182-Q
– ident: 10.1016/j.pneurobio.2004.05.005_bib325
  doi: 10.1111/j.1471-4159.2004.02707.x
– volume: 65
  start-page: 801
  year: 1996
  ident: 10.1016/j.pneurobio.2004.05.005_bib58
  article-title: Structure and functions of the 20 S and 26 S proteasome
  publication-title: Annu. Rev. Biochem.
  doi: 10.1146/annurev.bi.65.070196.004101
– volume: 110
  start-page: 1793
  year: 1997
  ident: 10.1016/j.pneurobio.2004.05.005_bib352
  article-title: Distinct subunit functions and cell cycle regulated phosphorylation of 20S APC/cyclosome required for anaphase in fission yeast
  publication-title: J. Cell Sci.
  doi: 10.1242/jcs.110.15.1793
– volume: 93
  start-page: 8040
  year: 1996
  ident: 10.1016/j.pneurobio.2004.05.005_bib37
  article-title: Induction of long-term potentiation is associated with major ultrastructural changes of activated synapses
  publication-title: Proc. Natl. Acad. Sci. U.S.A.
  doi: 10.1073/pnas.93.15.8040
– volume: 96
  start-page: 11364
  year: 1999
  ident: 10.1016/j.pneurobio.2004.05.005_bib188
  article-title: RING finger mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitination
  publication-title: Proc. Natl. Acad. Sci. U.S.A.
  doi: 10.1073/pnas.96.20.11364
– volume: 32
  start-page: 420
  year: 2002
  ident: 10.1016/j.pneurobio.2004.05.005_bib348
  article-title: Synaptic defects in ataxia mice result from a mutation in Usp14, encoding a ubiquitin-specific protease
  publication-title: Nat. Genet.
  doi: 10.1038/ng1006
– volume: 10
  start-page: 227
  year: 1991
  ident: 10.1016/j.pneurobio.2004.05.005_bib213
  article-title: UBAl: an essential yeast gene encoding ubiquitin-activating enzyme
  publication-title: EMBO J.
  doi: 10.1002/j.1460-2075.1991.tb07940.x
– volume: 40
  start-page: 314
  year: 2001
  ident: 10.1016/j.pneurobio.2004.05.005_bib280
  article-title: Assembly of the 26S proteasome is regulated by phosphorylation of the p45/Rpt6 ATPase subunit
  publication-title: Biochemistry
  doi: 10.1021/bi001815n
– volume: 15
  start-page: 7592
  year: 1995
  ident: 10.1016/j.pneurobio.2004.05.005_bib45
  article-title: Persistent activation of cAMP-dependent protein kinase by regulated proteolysis suggests a neuron-specific function of the ubiquitin system in Aplysia
  publication-title: J. Neurosci.
  doi: 10.1523/JNEUROSCI.15-11-07592.1995
– volume: 278
  start-page: 21323
  year: 2003
  ident: 10.1016/j.pneurobio.2004.05.005_bib225
  article-title: Endocytosis of receptor tyrosine kinases is driven by monoubiquitylation, not polyubiquitylation
  publication-title: J. Biol. Chem.
  doi: 10.1074/jbc.C300096200
– volume: 5
  start-page: 461
  year: 2003
  ident: 10.1016/j.pneurobio.2004.05.005_bib108
  article-title: Multiple monoubiquitination of RTKs is sufficient for their endocytosis and degradation
  publication-title: Nat. Cell Biol.
  doi: 10.1038/ncb983
– volume: 73
  start-page: 1075
  year: 1999
  ident: 10.1016/j.pneurobio.2004.05.005_bib231
  article-title: Activation of nuclear calcium dynamics by synaptic stimulation in cultured cortical neurons
  publication-title: J. Neurochem.
  doi: 10.1046/j.1471-4159.1999.0731075.x
– volume: 3
  start-page: 813
  year: 2002
  ident: 10.1016/j.pneurobio.2004.05.005_bib198
  article-title: Synaptic tagging—who’s it? Nat
  publication-title: Rev. Neurosci.
  doi: 10.1038/nrn942
– volume: 79
  start-page: 59
  year: 1994
  ident: 10.1016/j.pneurobio.2004.05.005_bib34
  article-title: Deficient long-term memory in mice with a targeted mutation of the cAMP-responsive element-binding protein
  publication-title: Cell
  doi: 10.1016/0092-8674(94)90400-6
– volume: 151
  start-page: 27
  year: 1992
  ident: 10.1016/j.pneurobio.2004.05.005_bib153
  article-title: Cell cycle-dependent change of proteasome distribution during embryonic development of the ascidian Halocynthia roretzi
  publication-title: Dev. Biol.
  doi: 10.1016/0012-1606(92)90210-8
– volume: 2
  start-page: 878
  year: 1999
  ident: 10.1016/j.pneurobio.2004.05.005_bib159
  article-title: Dendrites are more spiny on mature hippocampal neurons when synapses are inactivated
  publication-title: Nat. Neurosci.
  doi: 10.1038/13178
– volume: 920
  start-page: 28
  year: 2000
  ident: 10.1016/j.pneurobio.2004.05.005_bib259
  article-title: Genetics of Parkinson’s disease
  publication-title: Ann. NY Acad. Sci.
  doi: 10.1111/j.1749-6632.2000.tb06901.x
– volume: 33
  start-page: 1
  year: 1971
  ident: 10.1016/j.pneurobio.2004.05.005_bib328
  article-title: Rate and extent of recovery from dark rearing in the visual cortex of the mouse
  publication-title: Brain Res.
  doi: 10.1016/0006-8993(71)90302-7
– volume: 224
  start-page: 1057
  year: 1984
  ident: 10.1016/j.pneurobio.2004.05.005_bib192
  article-title: The biochemistry of memory: a new and specific hypothesis
  publication-title: Science
  doi: 10.1126/science.6144182
– volume: 73
  start-page: 2415
  year: 1999
  ident: 10.1016/j.pneurobio.2004.05.005_bib353
  article-title: Activation and degradation of the transcription factor C/EBP during long-term facilitation in Aplysia
  publication-title: J. Neurochem.
  doi: 10.1046/j.1471-4159.1999.0732415.x
– volume: 16
  start-page: 4540
  year: 1997
  ident: 10.1016/j.pneurobio.2004.05.005_bib255
  article-title: Sec61p mediates export of a misfolded secretory protein from the endoplasmic reticulum to the cytosol for degradation
  publication-title: EMBO J.
  doi: 10.1093/emboj/16.15.4540
– volume: 12
  start-page: 2556
  year: 2001
  ident: 10.1016/j.pneurobio.2004.05.005_bib330
  article-title: Proteasome inhibitors block a late step in lysosomal transport of selected membrane but not soluble proteins
  publication-title: Mol. Biol. Cell
  doi: 10.1091/mbc.12.8.2556
– volume: 395
  start-page: 451
  year: 1998
  ident: 10.1016/j.pneurobio.2004.05.005_bib172
  article-title: The ubiquitin pathway in Parkinson’s disease
  publication-title: Nature
  doi: 10.1038/26652
– volume: 92
  start-page: 713
  year: 1998
  ident: 10.1016/j.pneurobio.2004.05.005_bib260
  article-title: The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2’s inhibition of p53
  publication-title: Cell
  doi: 10.1016/S0092-8674(00)81400-2
– volume: 15
  start-page: 443
  year: 1987
  ident: 10.1016/j.pneurobio.2004.05.005_bib17
  article-title: The human ubiquitin gene family: structure of a gene and pseudogenes from the Ub B subfamily
  publication-title: Nucleic Acids Res.
  doi: 10.1093/nar/15.2.443
– volume: 182
  start-page: 1
  year: 2000
  ident: 10.1016/j.pneurobio.2004.05.005_bib163
  article-title: Modes of regulation of ubiquitin-mediated protein degradation
  publication-title: J. Cell. Physiol.
  doi: 10.1002/(SICI)1097-4652(200001)182:1<1::AID-JCP1>3.0.CO;2-V
– volume: 17
  start-page: 5001
  year: 1998
  ident: 10.1016/j.pneurobio.2004.05.005_bib308
  article-title: The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2
  publication-title: EMBO J.
  doi: 10.1093/emboj/17.17.5001
– volume: 256
  start-page: 645
  year: 1992
  ident: 10.1016/j.pneurobio.2004.05.005_bib14
  article-title: Serotonin-mediated endocytosis of apCAM: an early step of learning-related synaptic growth in Aplysia
  publication-title: Science
  doi: 10.1126/science.1585177
– volume: 35
  start-page: 590
  year: 2003
  ident: 10.1016/j.pneurobio.2004.05.005_bib349
  article-title: Deubiquitinating enzymes—the importance of driving in reverse along the ubiquitin-proteasome pathway
  publication-title: Int. J. Biochem. Cell Biol.
  doi: 10.1016/S1357-2725(02)00392-8
– volume: 276
  start-page: 33111
  year: 2001
  ident: 10.1016/j.pneurobio.2004.05.005_bib113
  article-title: U-box proteins as a new family of ubiquitin-protein ligases
  publication-title: J. Biol. Chem.
  doi: 10.1074/jbc.M102755200
– volume: 278
  start-page: 455
  year: 1997
  ident: 10.1016/j.pneurobio.2004.05.005_bib332
  article-title: Phosphorylation of Sic1p by G1 Cdk required for its degradation and entry into S phase
  publication-title: Science
  doi: 10.1126/science.278.5337.455
– volume: 14
  start-page: 3166
  year: 1994
  ident: 10.1016/j.pneurobio.2004.05.005_bib236
  article-title: bendless, a Drosophila gene affecting neuronal connectivity, encodes a ubiquitin-conjugating enzyme homolog
  publication-title: J. Neurosci.
  doi: 10.1523/JNEUROSCI.14-05-03166.1994
– volume: 276
  start-page: 12345
  year: 2001
  ident: 10.1016/j.pneurobio.2004.05.005_bib49
  article-title: Proteasome involvement in agonist-induced down-regulation of mu and delta opioid receptors
  publication-title: J. Biol. Chem.
  doi: 10.1074/jbc.M008054200
– volume: 20
  start-page: 5187
  year: 2001
  ident: 10.1016/j.pneurobio.2004.05.005_bib33
  article-title: A novel active site-directed probe specific for deubiquitylating enzymes reveals proteasome association of USP14
  publication-title: EMBO J.
  doi: 10.1093/emboj/20.18.5187
– volume: 268
  start-page: 6065
  year: 1993
  ident: 10.1016/j.pneurobio.2004.05.005_bib264
  article-title: The multicatalytic and 26S proteases
  publication-title: J. Biol. Chem.
  doi: 10.1016/S0021-9258(18)53218-X
– volume: 10
  start-page: 831
  year: 2002
  ident: 10.1016/j.pneurobio.2004.05.005_bib271
  article-title: SUMO-1 modification represses Sp3 transcriptional activation and modulates its subnuclear localization
  publication-title: Mol. Cell
  doi: 10.1016/S1097-2765(02)00682-2
– volume: 267
  start-page: 719
  year: 1992
  ident: 10.1016/j.pneurobio.2004.05.005_bib107
  article-title: A ubiquitin-C-terminal isopeptidase that acts on polyubiquitin chains: role in protein degradation
  publication-title: J. Biol. Chem.
  doi: 10.1016/S0021-9258(18)48343-3
– volume: 13
  start-page: 775
  year: 1993
  ident: 10.1016/j.pneurobio.2004.05.005_bib134
  article-title: Cloning and expression of the cDNA for E6-AP, a protein that mediates the interaction of the human papillomavirus E6 oncoprotein with p53
  publication-title: Mol. Cell. Biol.
  doi: 10.1128/MCB.13.2.775
– volume: 284
  start-page: 499
  year: 1999
  ident: 10.1016/j.pneurobio.2004.05.005_bib168
  article-title: Control of mRNA decay by heat shock-ubiquitin-proteasome pathway
  publication-title: Science
  doi: 10.1126/science.284.5413.499
– volume: 12
  start-page: 1002
  year: 2000
  ident: 10.1016/j.pneurobio.2004.05.005_bib40
  article-title: Tissue plasminogen activator controls multiple forms of synaptic plasticity and memory
  publication-title: Eur. J. Neurosci.
  doi: 10.1046/j.1460-9568.2000.00991.x
– volume: 15
  start-page: 70
  year: 1997
  ident: 10.1016/j.pneurobio.2004.05.005_bib160
  article-title: UBE3a/E6-AP mutations cause Angelman syndrome
  publication-title: Nat. Genet.
  doi: 10.1038/ng0197-70
– volume: 260
  start-page: 1573
  year: 1985
  ident: 10.1016/j.pneurobio.2004.05.005_bib254
  article-title: Functional heterogeneity of ubiquitin carrier proteins
  publication-title: J. Biol. Chem.
  doi: 10.1016/S0021-9258(18)89632-6
– ident: 10.1016/j.pneurobio.2004.05.005_bib324
– volume: 79
  start-page: 49
  year: 1994
  ident: 10.1016/j.pneurobio.2004.05.005_bib358
  article-title: Induction of a dominant negative CREB transgene specifically blocks long-term memory in Drosophila
  publication-title: Cell
  doi: 10.1016/0092-8674(94)90399-9
– volume: 18
  start-page: 3149
  year: 1998
  ident: 10.1016/j.pneurobio.2004.05.005_bib99
  article-title: The regulatory particle of the S. cerevisiae proteasome
  publication-title: Mol. Cell. Biol.
  doi: 10.1128/MCB.18.6.3149
– volume: 276
  start-page: 42938
  year: 2001
  ident: 10.1016/j.pneurobio.2004.05.005_bib144
  article-title: CHIP is a U-box-dependent E3 ubiquitin ligase: identification of Hsc70 as a target for ubiquitylation
  publication-title: J. Biol. Chem.
  doi: 10.1074/jbc.M101968200
– volume: 234
  start-page: 285
  year: 1999
  ident: 10.1016/j.pneurobio.2004.05.005_bib326
  article-title: Yeast tom1 mutant exhibits pleiotropic defects in nuclear division, maintenance of nuclear structure and nucleocytoplasmic transport at high temperatures
  publication-title: Gene
  doi: 10.1016/S0378-1119(99)00197-3
– volume: 82
  start-page: 373
  year: 2002
  ident: 10.1016/j.pneurobio.2004.05.005_bib97
  article-title: The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction
  publication-title: Physiol. Rev.
  doi: 10.1152/physrev.00027.2001
– volume: 416
  start-page: 535
  year: 2002
  ident: 10.1016/j.pneurobio.2004.05.005_bib337
  article-title: Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo
  publication-title: Nature
  doi: 10.1038/416535a
– volume: 4
  start-page: 1609
  year: 1985
  ident: 10.1016/j.pneurobio.2004.05.005_bib218
  article-title: Repetitive zinc-binding domains in the protein transcription factor IIIA from Xenopus oocytes
  publication-title: EMBO J.
  doi: 10.1002/j.1460-2075.1985.tb03825.x
– volume: 274
  start-page: 99
  year: 1996
  ident: 10.1016/j.pneurobio.2004.05.005_bib133
  article-title: Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice
  publication-title: Science
  doi: 10.1126/science.274.5284.99
– volume: 40
  start-page: 742
  year: 1973
  ident: 10.1016/j.pneurobio.2004.05.005_bib247
  article-title: Continuous illumination from birth affects spine density of neurons in the visual cortex of the rat
  publication-title: Exp. Neurol.
  doi: 10.1016/0014-4886(73)90108-8
– volume: 35
  start-page: 107
  year: 2002
  ident: 10.1016/j.pneurobio.2004.05.005_bib38
  article-title: Ubiquitin and AP180 regulate the abundance of GLR-1 glutamate receptors at postsynaptic elements in C. elegans
  publication-title: Neuron
  doi: 10.1016/S0896-6273(02)00749-3
– volume: 385
  start-page: 533
  year: 1997
  ident: 10.1016/j.pneurobio.2004.05.005_bib86
  article-title: Synaptic tagging and long-term potentiation
  publication-title: Nature
  doi: 10.1038/385533a0
– volume: 424
  start-page: 793
  year: 2003
  ident: 10.1016/j.pneurobio.2004.05.005_bib319
  article-title: CYLD is a deubiquitinating enzyme that negatively regulates NF-kappaB activation by TNFR family members
  publication-title: Nature
  doi: 10.1038/nature01803
– volume: 273
  start-page: 1725
  year: 1996
  ident: 10.1016/j.pneurobio.2004.05.005_bib124
  article-title: ER degradation of a misfolded luminal protein by the cytosolic ubiquitin-proteasome pathway
  publication-title: Science
  doi: 10.1126/science.273.5282.1725
– volume: 56
  start-page: 111
  year: 2001
  ident: 10.1016/j.pneurobio.2004.05.005_bib224
  article-title: Abnormalities in the synaptic vesicle fusion machinery in Huntington’s disease.
  publication-title: Brain Res. Bull.
  doi: 10.1016/S0361-9230(01)00611-6
– volume: 12
  start-page: 1293
  year: 2001
  ident: 10.1016/j.pneurobio.2004.05.005_bib268
  article-title: Involvement of the ubiquitin/proteasome system in sorting of the interleukin 2 receptor beta chain to late endocytic compartments.
  publication-title: Mol. Biol. Cell
  doi: 10.1091/mbc.12.5.1293
– volume: 271
  start-page: 15608
  year: 1996
  ident: 10.1016/j.pneurobio.2004.05.005_bib307
  article-title: The ubiquitin-activating enzyme E1 is phosphorylated and localized to the nucleus in a cell cycle-dependent manner
  publication-title: J. Biol. Chem.
  doi: 10.1074/jbc.271.26.15608
– volume: 9
  start-page: R551
  year: 1999
  ident: 10.1016/j.pneurobio.2004.05.005_bib356
  article-title: Giant proteases: beyond the proteasome
  publication-title: Curr. Biol.
  doi: 10.1016/S0960-9822(99)80352-2
– volume: 55
  start-page: 397
  year: 1993
  ident: 10.1016/j.pneurobio.2004.05.005_bib15
  article-title: Structural changes accompanying memory storage
  publication-title: Annu. Rev. Physiol.
  doi: 10.1146/annurev.ph.55.030193.002145
– volume: 18
  start-page: 621
  year: 2000
  ident: 10.1016/j.pneurobio.2004.05.005_bib150
  article-title: Phosphorylation meets ubiquitination: the control of NF-κB activity
  publication-title: Annu. Rev. Immunol.
  doi: 10.1146/annurev.immunol.18.1.621
– volume: 150
  start-page: 119
  year: 2000
  ident: 10.1016/j.pneurobio.2004.05.005_bib128
  article-title: The regulatory complex of Drosophila melanogaster 26S proteasomes. Subunit composition and localization of a deubiquitylating enzyme
  publication-title: J. Cell. Biol.
  doi: 10.1083/jcb.150.1.119
– volume: 270
  start-page: 27687
  year: 1995
  ident: 10.1016/j.pneurobio.2004.05.005_bib355
  article-title: In vivo assembly of the proteasomal complexes, implications for antigen processing
  publication-title: J. Biol. Chem.
  doi: 10.1074/jbc.270.46.27687
– volume: 74
  start-page: 2607
  year: 2000
  ident: 10.1016/j.pneurobio.2004.05.005_bib85
  article-title: A synthetic peptide ligand of neural cell adhesion molecule (NCAM) IgI domain prevents NCAM internalization and disrupts passive avoidance learning
  publication-title: J. Neurochem.
  doi: 10.1046/j.1471-4159.2000.0742607.x
– volume: 9
  start-page: 207
  year: 1999
  ident: 10.1016/j.pneurobio.2004.05.005_bib111
  article-title: The F-box protein beta-TrCP associates with phosphorylated betaβ-catenin and regulates its activity in the cell
  publication-title: Curr. Biol.
  doi: 10.1016/S0960-9822(99)80091-8
– volume: 28
  start-page: 321
  year: 2003
  ident: 10.1016/j.pneurobio.2004.05.005_bib286
  article-title: A superfamily of protein tags: ubiquitin. SUMO and related modifiers
  publication-title: Trends Biochem. Sci.
  doi: 10.1016/S0968-0004(03)00113-0
– volume: 21
  start-page: 27
  year: 1995
  ident: 10.1016/j.pneurobio.2004.05.005_bib76
  article-title: Subunits of the regulatory complex of the 26S proteasome
  publication-title: Mol. Biol. Rep.
  doi: 10.1007/BF00990967
– volume: 238
  start-page: 236
  year: 1985
  ident: 10.1016/j.pneurobio.2004.05.005_bib304
  article-title: The transient corticospinal projection from the occipital cortex during the postnatal development of the rat
  publication-title: J. Comp. Neurol.
  doi: 10.1002/cne.902380210
– volume: 20
  start-page: 7096
  year: 2001
  ident: 10.1016/j.pneurobio.2004.05.005_bib90
  article-title: Subunit interaction maps for the regulatory particle of the 26s proteasome and the cop9 signalosome reveal a conserved core structure
  publication-title: EMBO J.
  doi: 10.1093/emboj/20.24.7096
– volume: 312
  start-page: 101
  year: 1984
  ident: 10.1016/j.pneurobio.2004.05.005_bib59
  article-title: Memory and molecular turnover
  publication-title: Nature
  doi: 10.1038/312101a0
– volume: 627
  start-page: 181
  year: 1991
  ident: 10.1016/j.pneurobio.2004.05.005_bib13
  article-title: Morphological aspects of synaptic plasticity in Aplysia. An anatomical substrate for long-term memory
  publication-title: Ann. N.Y. Acad. Sci.
  doi: 10.1111/j.1749-6632.1991.tb25924.x
– volume: 12
  start-page: 3663
  year: 1998
  ident: 10.1016/j.pneurobio.2004.05.005_bib177
  article-title: c-Cbl regulates endocytic sorting and ubiquitination of the epidermal growth factor receptor
  publication-title: Genes Dev.
  doi: 10.1101/gad.12.23.3663
– volume: 116
  start-page: PE4
  year: 2002
  ident: 10.1016/j.pneurobio.2004.05.005_bib250
  article-title: A new gun in town: the U box is a ubiquitin ligase domain
  publication-title: Sci STKE
– volume: 534
  start-page: 317
  year: 1990
  ident: 10.1016/j.pneurobio.2004.05.005_bib69
  article-title: Calpain inhibitors block long-term potentiation
  publication-title: Brain Res.
  doi: 10.1016/0006-8993(90)90148-5
– volume: 96
  start-page: 635
  year: 1999
  ident: 10.1016/j.pneurobio.2004.05.005_bib162
  article-title: A novel ubiquitination factor, E4, is involved in multiubiquitin chain assembly
  publication-title: Cell
  doi: 10.1016/S0092-8674(00)80574-7
– volume: 25
  start-page: 302
  year: 2000
  ident: 10.1016/j.pneurobio.2004.05.005_bib295
  article-title: Familial Parkinson disease gene product, Parkin, is a ubiquitin-protein ligase
  publication-title: Nat. Genet.
  doi: 10.1038/77060
– volume: 386
  start-page: 89
  year: 2001
  ident: 10.1016/j.pneurobio.2004.05.005_bib112
  article-title: Quaternary structure of the ATPase complex of human 26S proteasomes determined by chemical cross-linking
  publication-title: Arch. Biochem. Biophys.
  doi: 10.1006/abbi.2000.2178
– volume: 103
  start-page: 667
  year: 1999
  ident: 10.1016/j.pneurobio.2004.05.005_bib4
  article-title: Defective regulation of the epithelial Na+ channel by Nedd4 in Liddle’s syndrome
  publication-title: J. Clin. Invest.
  doi: 10.1172/JCI5713
– volume: 430
  start-page: 269
  year: 1998
  ident: 10.1016/j.pneurobio.2004.05.005_bib201
  article-title: Phosphorylation of ATPase subunits of the 26S proteasome
  publication-title: FEBS Lett.
  doi: 10.1016/S0014-5793(98)00676-0
– volume: 71
  start-page: 1298
  year: 1998
  ident: 10.1016/j.pneurobio.2004.05.005_bib241
  article-title: Persistence of the interaction of calmodulin with adenylyl cyclase: implications for integration of transient calcium stimuli
  publication-title: J. Neurochem.
  doi: 10.1046/j.1471-4159.1998.71031298.x
– ident: 10.1016/j.pneurobio.2004.05.005_bib209
  doi: 10.1038/35055162
– volume: 31
  start-page: 289
  year: 2001
  ident: 10.1016/j.pneurobio.2004.05.005_bib244
  article-title: Regulation of dendritic spine morphology by SPAR, a PSD-95-associated RapGAP
  publication-title: Neuron.
  doi: 10.1016/S0896-6273(01)00355-5
– volume: 275
  start-page: 8945
  year: 2000
  ident: 10.1016/j.pneurobio.2004.05.005_bib80
  article-title: Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53
  publication-title: J. Biol. Chem.
  doi: 10.1074/jbc.275.12.8945
– volume: 268
  start-page: 533
  year: 1995
  ident: 10.1016/j.pneurobio.2004.05.005_bib185
  article-title: Crystal structure of the 20S proteasome from the archeon T. acidophilum at 3.4 Angstrom resolution
  publication-title: Science
  doi: 10.1126/science.7725097
– volume: 20
  start-page: 5115
  year: 2000
  ident: 10.1016/j.pneurobio.2004.05.005_bib227
  article-title: Abnormal synaptic plasticity and impaired spatial cognition in mice transgenic for exon 1 of the human Huntington’s disease mutation
  publication-title: J. Neurosci.
  doi: 10.1523/JNEUROSCI.20-13-05115.2000
– volume: 10
  start-page: 17
  year: 2000
  ident: 10.1016/j.pneurobio.2004.05.005_bib318
  article-title: The roles of E6-AP and MDM2 in p53 regulation in human papillomavirus-positive cervical cancer cells
  publication-title: Antisense. Nucleic Acid Drug Dev.
  doi: 10.1089/oli.1.2000.10.17
– volume: 272
  start-page: 13403
  year: 1997
  ident: 10.1016/j.pneurobio.2004.05.005_bib266
  article-title: Specific interactions between ATPase subunits of the 26S proteasome
  publication-title: J. Biol. Chem.
  doi: 10.1074/jbc.272.20.13403
– volume: 95
  start-page: 637
  year: 1998
  ident: 10.1016/j.pneurobio.2004.05.005_bib312
  article-title: The role of tricorn protease and its aminopeptidase-interacting factors in cellular protein degradation
  publication-title: Cell
  doi: 10.1016/S0092-8674(00)81634-7
– volume: 10
  start-page: R132
  year: 2000
  ident: 10.1016/j.pneurobio.2004.05.005_bib6
  article-title: The U box is a modified RING finger: a common domain in ubiquitination
  publication-title: Curr. Biol.
  doi: 10.1016/S0960-9822(00)00398-5
– volume: 424
  start-page: 801
  year: 2003
  ident: 10.1016/j.pneurobio.2004.05.005_bib165
  article-title: The tumour suppressor CYLD negatively regulates NF-κB signalling by deubiquitination
  publication-title: Nature
  doi: 10.1038/nature01802
– volume: 12
  start-page: 1112
  year: 2002
  ident: 10.1016/j.pneurobio.2004.05.005_bib238
  article-title: The ubiquitin-interacting motifs target the endocytic adaptor protein epsin for ubiquitination
  publication-title: Curr. Biol.
  doi: 10.1016/S0960-9822(02)00900-4
– volume: 275
  start-page: 18557
  year: 2000
  ident: 10.1016/j.pneurobio.2004.05.005_bib211
  article-title: cDNA cloning, expression, and functional characterization of PI31, a proline-rich inhibitor of the proteasome
  publication-title: J. Biol. Chem.
  doi: 10.1074/jbc.M001697200
– volume: 412
  start-page: 346
  year: 2001
  ident: 10.1016/j.pneurobio.2004.05.005_bib339
  article-title: Tak1 is a ubiquitin-dependent kinase of MKK and IKK
  publication-title: Nature
  doi: 10.1038/35085597
– volume: 92
  start-page: 2563
  year: 1995
  ident: 10.1016/j.pneurobio.2004.05.005_bib135
  article-title: A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase
  publication-title: Proc. Natl. Acad. Sci. U.S.A.
  doi: 10.1073/pnas.92.7.2563
– volume: 10
  start-page: 1049
  year: 2001
  ident: 10.1016/j.pneurobio.2004.05.005_bib139
  article-title: Altered proteasomal function due to the expression of polyglutamine-expanded truncated N-terminal huntingtin induces apoptosis by caspase activation through mitochondrial cytochrome c release
  publication-title: Hum. Mol. Genet.
  doi: 10.1093/hmg/10.10.1049
– volume: 416
  start-page: 451
  year: 2002
  ident: 10.1016/j.pneurobio.2004.05.005_bib258
  article-title: A single motif responsible for ubiquitin recognition and monoubiquitination in endocytic proteins
  publication-title: Nature
  doi: 10.1038/416451a
– volume: 396
  start-page: 590
  year: 1998
  ident: 10.1016/j.pneurobio.2004.05.005_bib357
  article-title: Identification of the receptor component of the IkB-ubiquitin ligase
  publication-title: Nature
  doi: 10.1038/25159
– volume: 37
  start-page: 545
  year: 1998
  ident: 10.1016/j.pneurobio.2004.05.005_bib89
  article-title: Weak before strong: dissociating synaptic tagging and plasticity-factor accounts of late-LTP
  publication-title: Neuropharmacology
  doi: 10.1016/S0028-3908(98)00040-9
– volume: 11
  start-page: 1189
  year: 2003
  ident: 10.1016/j.pneurobio.2004.05.005_bib336
  article-title: The F-box protein Skp2 participates in c-Myc proteosomal degradation and acts as a cofactor for c-Myc-regulated transcription
  publication-title: Mol. Cell
  doi: 10.1016/S1097-2765(03)00193-X
– volume: 150
  start-page: 905
  year: 2000
  ident: 10.1016/j.pneurobio.2004.05.005_bib55
  article-title: Tyrosine phosphorylation of Eps15 is required for ligand-regulated, but not constitutive, endocytosis
  publication-title: J. Cell Biol.
  doi: 10.1083/jcb.150.4.905
– volume: 141
  start-page: 1415
  year: 1998
  ident: 10.1016/j.pneurobio.2004.05.005_bib114
  article-title: A giant ubiquitin-conjugating enzyme related to IAP apoptosis inhibitors
  publication-title: J. Cell. Biol.
  doi: 10.1083/jcb.141.6.1415
– volume: 8
  start-page: 763
  year: 1999
  ident: 10.1016/j.pneurobio.2004.05.005_bib291
  article-title: A Huntington’s disease CAG expansion at the murine Hdh locus is unstable and associated with behavioural abnormalities in mice
  publication-title: Hum. Mol. Genet.
  doi: 10.1093/hmg/8.5.763
– volume: 18
  start-page: 3007
  year: 1999
  ident: 10.1016/j.pneurobio.2004.05.005_bib193
  article-title: Enhanced hippocampal long-term potentiation and learning by increased neuronal expression of tissue-type plasminogen activator in transgenic mice
  publication-title: EMBO J.
  doi: 10.1093/emboj/18.11.3007
– volume: 21
  start-page: 8772
  year: 2001
  ident: 10.1016/j.pneurobio.2004.05.005_bib200
  article-title: Proteasomal-dependent aggregate reversal and absence of cell death in a conditional mouse model of Huntington’s disease
  publication-title: J. Neurosci.
  doi: 10.1523/JNEUROSCI.21-22-08772.2001
– volume: 25
  start-page: 868
  year: 2003
  ident: 10.1016/j.pneurobio.2004.05.005_bib210
  article-title: Evolving questions and paradigm shifts in endoplasmic-reticulum-associated degradation (ERAD)
  publication-title: Bioessays.
  doi: 10.1002/bies.10320
– volume: 58
  start-page: 598
  year: 1995
  ident: 10.1016/j.pneurobio.2004.05.005_bib173
  article-title: Comparison of executive and visuospatial memory function in Huntington’s disease and dementia of Alzheimer type matched for degree of dementia
  publication-title: J. Neurol. Neurosurg. Psychiatr.
  doi: 10.1136/jnnp.58.5.598
– volume: 17
  start-page: 655
  year: 1996
  ident: 10.1016/j.pneurobio.2004.05.005_bib284
  article-title: Genetic dissection of structural and functional components of synaptic plasticity. II. Fasciclin II controls presynaptic structural plasticity
  publication-title: Neuron
  doi: 10.1016/S0896-6273(00)80198-1
– volume: 13
  start-page: 2073
  year: 2003
  ident: 10.1016/j.pneurobio.2004.05.005_bib249
  article-title: Ubiquitin-mediated proteasome activity is required for agonist-induced endocytosis of GluRs
  publication-title: Curr. Biol.
  doi: 10.1016/j.cub.2003.10.028
– volume: 654
  start-page: 129
  year: 1994
  ident: 10.1016/j.pneurobio.2004.05.005_bib190
  article-title: Dendritic spine density in the lobus parolfactorius of the domestic chick is increased 24h after one-trial passive avoidance training.
  publication-title: Brain Res.
  doi: 10.1016/0006-8993(94)91578-4
– volume: 13
  start-page: 899
  year: 2003
  ident: 10.1016/j.pneurobio.2004.05.005_bib302
  article-title: The ubiquitin proteasome system acutely regulates presynaptic protein turnover and synaptic efficacy
  publication-title: Curr. Biol.
  doi: 10.1016/S0960-9822(03)00338-5
– volume: 268
  start-page: 726
  year: 1995
  ident: 10.1016/j.pneurobio.2004.05.005_bib81
  article-title: Inhibition of proteasome activities and subunit-specific amino-terminal threonine modification by lactacystin
  publication-title: Science
  doi: 10.1126/science.7732382
– volume: 76
  start-page: 424
  year: 2000
  ident: 10.1016/j.pneurobio.2004.05.005_bib118
  article-title: Structure and expression of the Aplysia polyubiquitin gene
  publication-title: Brain Res. Mol. Brain Res.
  doi: 10.1016/S0169-328X(00)00021-8
– volume: 275
  start-page: 400
  year: 1997
  ident: 10.1016/j.pneurobio.2004.05.005_bib228
  article-title: Reduced ubiquitin-dependent degradation of c-Jun after phosphorylation by MAP kinases
  publication-title: Science
  doi: 10.1126/science.275.5298.400
– volume: 284
  start-page: 901
  year: 1999
  ident: 10.1016/j.pneurobio.2004.05.005_bib321
  article-title: One RING to rule a superfamily of E3 ubiquitin ligases
  publication-title: Science
  doi: 10.1126/science.284.5414.601
– volume: 21
  start-page: 181
  year: 1998
  ident: 10.1016/j.pneurobio.2004.05.005_bib88
  article-title: Synaptic tagging: implications for late maintenance of hippocampal long-term potentiation
  publication-title: Trends Neurosci.
  doi: 10.1016/S0166-2236(97)01189-2
– volume: 12
  start-page: 901
  year: 1998
  ident: 10.1016/j.pneurobio.2004.05.005_bib126
  article-title: There’s the rub: a novel ubiquitin-like modification linked to cell cycle regulation
  publication-title: Genes Dev.
  doi: 10.1101/gad.12.7.901
– ident: 10.1016/j.pneurobio.2004.05.005_bib29
  doi: 10.1016/j.cub.2003.10.028
– volume: 270
  start-page: 1850
  year: 1995
  ident: 10.1016/j.pneurobio.2004.05.005_bib64
  article-title: Developmental changes of the 26S proteasome in abdominal intersegmental muscles of Manduca sexta during programmed cell death
  publication-title: J. Biol. Chem.
  doi: 10.1074/jbc.270.4.1850
– volume: 269
  start-page: 20878
  year: 1994
  ident: 10.1016/j.pneurobio.2004.05.005_bib67
  article-title: PA700, an ATP-dependent activator of the 20S proteasome, is an ATPase containing multiple members of a nucleotide binding protein family
  publication-title: J. Biol. Chem.
  doi: 10.1016/S0021-9258(17)31904-X
– volume: 3
  start-page: 854
  year: 2002
  ident: 10.1016/j.pneurobio.2004.05.005_bib115
  article-title: Ubiquitin and the synapse
  publication-title: Nat. Rev. Neurosci.
  doi: 10.1038/nrn961
– volume: 244
  start-page: 1480
  year: 1989
  ident: 10.1016/j.pneurobio.2004.05.005_bib206
  article-title: Degradation of proteins with acetylated amino termini by the ubiquitin system
  publication-title: Science
  doi: 10.1126/science.2544030
– volume: 277
  start-page: 35071
  year: 2002
  ident: 10.1016/j.pneurobio.2004.05.005_bib51
  article-title: Staring, a novel E3 ubiquitin-protein ligase that targets syntaxin 1 for degradation
  publication-title: J. Biol. Chem.
  doi: 10.1074/jbc.M203300200
– volume: 277
  start-page: 10273
  year: 2002
  ident: 10.1016/j.pneurobio.2004.05.005_bib342
  article-title: Regulation of synaptophysin degradation by mammalian homologues of seven in absentia
  publication-title: J. Biol. Chem.
  doi: 10.1074/jbc.M107857200
– volume: 32
  start-page: 1013
  year: 2001
  ident: 10.1016/j.pneurobio.2004.05.005_bib41
  article-title: Chemotropic responses of retinal growth cones mediated by rapid local protein synthesis and degradation
  publication-title: Neuron
  doi: 10.1016/S0896-6273(01)00551-7
– volume: 21
  start-page: 799
  year: 1998
  ident: 10.1016/j.pneurobio.2004.05.005_bib145
  article-title: Mutation of the Angelman ubiquitin ligase in mice causes increased cytoplasmic p53 and deficits of contextual learning and long-term potentiation
  publication-title: Neuron
  doi: 10.1016/S0896-6273(00)80596-6
– volume: 68
  start-page: 583
  year: 1999
  ident: 10.1016/j.pneurobio.2004.05.005_bib242
  article-title: The anaphase-promoting complex: new substrates and regulators
  publication-title: Annu. Rev. Biochem.
  doi: 10.1146/annurev.biochem.68.1.583
– volume: 23
  start-page: 47
  year: 1999
  ident: 10.1016/j.pneurobio.2004.05.005_bib279
  article-title: Intragenic deletion in the gene encoding ubiquitin carboxy-terminal hydrolase in gad mice
  publication-title: Nat. Genet.
  doi: 10.1038/12647
– volume: 19
  start-page: 5502
  year: 2000
  ident: 10.1016/j.pneurobio.2004.05.005_bib253
  article-title: Importin-11, a nuclear import receptor for the ubiquitin-conjugating enzyme, UbcM2
  publication-title: EMBO J.
  doi: 10.1093/emboj/19.20.5502
– volume: 21
  start-page: 1833
  year: 2002
  ident: 10.1016/j.pneurobio.2004.05.005_bib216
  article-title: Differential mRNA translation and meiotic progression require Cdc2-mediated CPEB destruction
  publication-title: EMBO J.
  doi: 10.1093/emboj/21.7.1833
– volume: 287
  start-page: 501
  year: 2000
  ident: 10.1016/j.pneurobio.2004.05.005_bib267
  article-title: Rad6-dependent ubiquitination of histone H2B in yeast
  publication-title: Science
  doi: 10.1126/science.287.5452.501
– volume: 2
  start-page: 571
  year: 1998
  ident: 10.1016/j.pneurobio.2004.05.005_bib364
  article-title: Ubiquitination and degradation of the substrate recognition subunits of SCF ubiquitin-protein ligases
  publication-title: Mol. Cell
  doi: 10.1016/S1097-2765(00)80156-2
– volume: 48
  start-page: 45
  year: 1992
  ident: 10.1016/j.pneurobio.2004.05.005_bib261
  article-title: Repeated changes of dendritic morphology in the hippocampus of ground squirrels in the course of hibernation
  publication-title: Neuroscience
  doi: 10.1016/0306-4522(92)90336-Z
– volume: 108
  start-page: 345
  year: 2002
  ident: 10.1016/j.pneurobio.2004.05.005_bib26
  article-title: Structural basis for E2-mediated SUMO conjugation revealed by a complex between ubiquitin-conjugating enzyme Ubc9 and RanGAP1
  publication-title: Cell
  doi: 10.1016/S0092-8674(02)00630-X
– volume: 10
  start-page: 2583
  year: 1999
  ident: 10.1016/j.pneurobio.2004.05.005_bib309
  article-title: The Doa4 deubiquitinating enzyme is required for ubiquitin homeostasis in yeast
  publication-title: Mol. Biol. Cell
  doi: 10.1091/mbc.10.8.2583
– volume: 256
  start-page: 638
  year: 1992
  ident: 10.1016/j.pneurobio.2004.05.005_bib207
  article-title: Modulation of an NCAM-related adhesion molecule with long-term synaptic plasticity in Aplysia
  publication-title: Science
  doi: 10.1126/science.1585176
– volume: 97
  start-page: 8501
  year: 2000
  ident: 10.1016/j.pneurobio.2004.05.005_bib123
  article-title: Activation of p53 in cervical carcinoma cells by small molecules
  publication-title: Proc. Natl. Acad. Sci. U.S.A.
  doi: 10.1073/pnas.97.15.8501
– volume: 9
  start-page: 529
  year: 2000
  ident: 10.1016/j.pneurobio.2004.05.005_bib272
  article-title: Regulation of the epithelial sodium channel (ENaC) by accessory proteins
  publication-title: Curr. Opin. Nephrol. Hypertens.
  doi: 10.1097/00041552-200009000-00012
– volume: 276
  start-page: 42978
  year: 2001
  ident: 10.1016/j.pneurobio.2004.05.005_bib39
  article-title: Ubiquitination precedes internalization and proteolytic cleavage of plasma membrane-bound glycine receptors
  publication-title: J. Biol. Chem.
  doi: 10.1074/jbc.M102121200
– volume: 253
  start-page: 476
  year: 1986
  ident: 10.1016/j.pneurobio.2004.05.005_bib71
  article-title: Changes in the postsynaptic density with long-term potentiation in the dentate gyrus
  publication-title: J. Comp. Neurol.
  doi: 10.1002/cne.902530405
– volume: 95
  start-page: 1
  year: 1998
  ident: 10.1016/j.pneurobio.2004.05.005_bib20
  article-title: CREB-1 encodes a nuclear activator, a repressor and a cytoplasmic modulator that together constitute a regulatory unit critical for long-term facilitation in Aplysia
  publication-title: Cell
  doi: 10.1016/S0092-8674(00)81752-3
– volume: 14
  start-page: 3158
  year: 1994
  ident: 10.1016/j.pneurobio.2004.05.005_bib125
  article-title: The Glc7 type 1 protein phosphatase of Saccharomyces cerevisiae is required for cell cycle progression in G2/M
  publication-title: Mol. Cell. Biol.
  doi: 10.1128/MCB.14.5.3158
– volume: 7
  start-page: 1121
  year: 1988
  ident: 10.1016/j.pneurobio.2004.05.005_bib310
  article-title: The genomic organization and transcription of the ubiquitin genes of Trypanosoma cruzi
  publication-title: EMBO J.
  doi: 10.1002/j.1460-2075.1988.tb02921.x
– volume: 424
  start-page: 797
  year: 2003
  ident: 10.1016/j.pneurobio.2004.05.005_bib36
  article-title: Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-κB
  publication-title: Nature
  doi: 10.1038/nature01811
– volume: 3
  start-page: 337
  year: 1967
  ident: 10.1016/j.pneurobio.2004.05.005_bib327
  article-title: Apical dendritic spines of the visual cortex and light deprivation in the mouse
  publication-title: Exp. Brain Res.
  doi: 10.1007/BF00237559
– volume: 88
  start-page: 139
  year: 1991
  ident: 10.1016/j.pneurobio.2004.05.005_bib53
  article-title: Degradation of nuelar oncoproteins by the ubiquitin sytem in vitro
  publication-title: Proc. Natl. Acad. Sci. U.S.A.
  doi: 10.1073/pnas.88.1.139
– volume: 11
  start-page: 261
  year: 2003
  ident: 10.1016/j.pneurobio.2004.05.005_bib137
  article-title: A conserved RING finger protein required for histone H2B monoubiquitination and cell size control
  publication-title: Mol. Cell
  doi: 10.1016/S1097-2765(02)00826-2
– volume: 19
  start-page: 94
  year: 2000
  ident: 10.1016/j.pneurobio.2004.05.005_bib315
  article-title: Recognition of the polyubiquitin proteolytic signal
  publication-title: EMBO J.
  doi: 10.1093/emboj/19.1.94
– volume: 395
  start-page: 395
  year: 1998
  ident: 10.1016/j.pneurobio.2004.05.005_bib219
  article-title: A protein conjugation system essential for autophagy
  publication-title: Nature
  doi: 10.1038/26506
– volume: 186
  start-page: 261
  year: 1999
  ident: 10.1016/j.pneurobio.2004.05.005_bib316
  article-title: Nature and role of proteasome in fish oocytes
  publication-title: Int. Rev. Cytol.
  doi: 10.1016/S0074-7696(08)61056-6
– volume: 424
  start-page: 1009
  year: 2003
  ident: 10.1016/j.pneurobio.2004.05.005_bib223
  article-title: Cks1-dependent proteasome recruitment and activation of CDC20 transcription in budding yeast
  publication-title: Nature
  doi: 10.1038/nature01720
– volume: 131
  start-page: 27
  year: 2003
  ident: 10.1016/j.pneurobio.2004.05.005_bib220
  article-title: Identification and characterization of the ARIADNE gene family in Arabidopsis. A group of putative E3 ligases
  publication-title: Plant Physiol.
  doi: 10.1104/pp.012781
– volume: 37
  start-page: 3358
  year: 1998
  ident: 10.1016/j.pneurobio.2004.05.005_bib170
  article-title: Substrate specificity of deubiquitinating enzymes: ubiquitin C-terminal hydrolases
  publication-title: Biochemistry
  doi: 10.1021/bi972274d
– volume: 94
  start-page: 615
  year: 1998
  ident: 10.1016/j.pneurobio.2004.05.005_bib98
  article-title: A subcomplex of the proteasome regulatory particle required for ubiquitin-conjugate degradation and related to the COP9/Signalosome and eIF3
  publication-title: Cell
  doi: 10.1016/S0092-8674(00)81603-7
– volume: 3
  start-page: 28
  year: 2002
  ident: 10.1016/j.pneurobio.2004.05.005_bib205
  article-title: MPN+, a putative catalytic motif found in a subset of MPN domain proteins from eukaryotes and prokaryotes, is critical for Rpn11 function
  publication-title: BMC Biochem.
  doi: 10.1186/1471-2091-3-28
– volume: 153
  start-page: 649
  year: 2001
  ident: 10.1016/j.pneurobio.2004.05.005_bib119
  article-title: Components of a ubiquitin ligase complex specify polyubiquitination and intracellular trafficking of the general amino acid permease
  publication-title: J. Cell. Biol.
  doi: 10.1083/jcb.153.4.649
– volume: 28
  start-page: 280
  year: 2003
  ident: 10.1016/j.pneurobio.2004.05.005_bib322
  article-title: A potential proteasome-interacting motif within the ubiquitin-like domain of parkin and other proteins
  publication-title: Trends Biochem. Sci.
  doi: 10.1016/S0968-0004(03)00092-6
– volume: 2
  start-page: 821
  year: 2001
  ident: 10.1016/j.pneurobio.2004.05.005_bib63
  article-title: A protein-protein map of the C. elegans 26S proteasome
  publication-title: EMBO Rep.
  doi: 10.1093/embo-reports/kve184
– volume: 345
  start-page: 718
  year: 1990
  ident: 10.1016/j.pneurobio.2004.05.005_bib61
  article-title: Injection of the cAMP-responsive element into the nucleus of Aplysia sensory neurons blocks long-term facilitation
  publication-title: Nature
  doi: 10.1038/345718a0
– volume: 412
  start-page: 449
  year: 2001
  ident: 10.1016/j.pneurobio.2004.05.005_bib73
  article-title: Ubiquitination-dependent mechanisms regulate synaptic growth and function
  publication-title: Nature
  doi: 10.1038/35086595
– volume: 88
  start-page: 258
  year: 1991
  ident: 10.1016/j.pneurobio.2004.05.005_bib109
  article-title: Molecular cloning, sequence, and tissue distribution of the human ubiquitin-activating enzyme, E1
  publication-title: Proc. Natl. Acad. Sci. U.S.A.
  doi: 10.1073/pnas.88.1.258
– volume: 4
  start-page: 134
  year: 2002
  ident: 10.1016/j.pneurobio.2004.05.005_bib140
  article-title: Protein dislocation from the ER requires polyubiquitination and the AAA-ATPase Cdc48
  publication-title: Nat. Cell Biol.
  doi: 10.1038/ncb746
– volume: 278
  start-page: 1806
  year: 1997
  ident: 10.1016/j.pneurobio.2004.05.005_bib28
  article-title: Role of Cue1p in ubiquitination and degradation at the ER surface
  publication-title: Science
  doi: 10.1126/science.278.5344.1806
– volume: 11
  start-page: 267
  year: 2003
  ident: 10.1016/j.pneurobio.2004.05.005_bib351
  article-title: Bre1, an E3 ubiquitin ligase required for recruitment and substrate selection of Rad6 at a promoter
  publication-title: Mol. Cell
  doi: 10.1016/S1097-2765(02)00802-X
– volume: 10
  start-page: 495
  year: 2002
  ident: 10.1016/j.pneurobio.2004.05.005_bib171
  article-title: Multiple associated proteins regulate proteasome structure and function
  publication-title: Mol. Cell
  doi: 10.1016/S1097-2765(02)00638-X
– volume: 106
  start-page: 145
  year: 2001
  ident: 10.1016/j.pneurobio.2004.05.005_bib151
  article-title: Ubiquitin-dependent sorting into the multivesicular body pathway requires the function of a conserved endosomal protein sorting complex, ESCRT-I
  publication-title: Cell
  doi: 10.1016/S0092-8674(01)00434-2
– volume: 96
  start-page: 1858
  year: 1999
  ident: 10.1016/j.pneurobio.2004.05.005_bib233
  article-title: Proteasome-dependent degradation of the human estrogen receptor
  publication-title: Proc. Natl. Acad. Sci. U.S.A.
  doi: 10.1073/pnas.96.5.1858
– volume: 97
  start-page: 3118
  year: 2000
  ident: 10.1016/j.pneurobio.2004.05.005_bib275
  article-title: Functional overlap of sequences that activate transcription and signal ubiquitin-mediated proteolysis
  publication-title: Proc. Natl. Acad. Sci. U.S.A.
  doi: 10.1073/pnas.050007597
– volume: 4
  start-page: 1029
  year: 1999
  ident: 10.1016/j.pneurobio.2004.05.005_bib178
  article-title: Ubiquitin ligase activity and tyrosine phosphorylation underlie suppression of growth factor signaling by c-Cbl/Sli-1
  publication-title: Mol. Cell
  doi: 10.1016/S1097-2765(00)80231-2
– volume: 3
  start-page: 100
  year: 2001
  ident: 10.1016/j.pneurobio.2004.05.005_bib214
  article-title: The Hsc70 co-chaperone CHIP targets immature CFTR for proteasomal degradation
  publication-title: Nat. Cell Biol.
  doi: 10.1038/35050509
– volume: 79
  start-page: 233
  year: 1994
  ident: 10.1016/j.pneurobio.2004.05.005_bib288
  article-title: The B-type cyclin kinase inhibitor p40-SIC1 controls the G1 to S transition in S. cerevisiae
  publication-title: Cell
  doi: 10.1016/0092-8674(94)90193-7
– volume: 97
  start-page: 13354
  year: 2000
  ident: 10.1016/j.pneurobio.2004.05.005_bib362
  article-title: Parkin functions as an E2-dependent ubiquitin-protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1
  publication-title: Proc. Natl. Acad. Sci. U.S.A.
  doi: 10.1073/pnas.240347797
– volume: 12
  start-page: 4021
  year: 1993
  ident: 10.1016/j.pneurobio.2004.05.005_bib235
  article-title: Degradation of Mos by the N-terminal proline (Pro2)-dependent ubiquitin pathway on fertilization of Xenopus eggs: possible significance of natural selection for Pro2 in Mos
  publication-title: EMBO J.
  doi: 10.1002/j.1460-2075.1993.tb06080.x
– volume: 231
  start-page: 447
  year: 2001
  ident: 10.1016/j.pneurobio.2004.05.005_bib265
  article-title: CPEB degradation during Xenopus oocyte maturation requires a PEST domain and the 26S proteasome
  publication-title: Dev. Biol.
  doi: 10.1006/dbio.2001.0153
– volume: 19
  start-page: 215
  year: 1996
  ident: 10.1016/j.pneurobio.2004.05.005_bib300
  article-title: Mechanisms for the generation of synapse specificity in long-term memory: the implications of a requirement for transcription
  publication-title: Trends Neurosci.
– volume: 9
  start-page: 749
  year: 1992
  ident: 10.1016/j.pneurobio.2004.05.005_bib16
  article-title: Inhibitors of protein and RNA synthesis block structural changes that accompany long-term heterosynaptic plasticity in Aplysia
  publication-title: Neuron
  doi: 10.1016/0896-6273(92)90037-E
– volume: 11
  start-page: 1569
  year: 2001
  ident: 10.1016/j.pneurobio.2004.05.005_bib66
  article-title: Cooperation of a ubiquitin domain protein and an E3 ubiquitin ligase during chaperone/proteasome coupling
  publication-title: Curr. Biol.
  doi: 10.1016/S0960-9822(01)00487-0
– volume: 6
  start-page: 231
  year: 2003
  ident: 10.1016/j.pneurobio.2004.05.005_bib79
  article-title: Activity level controls postsynaptic composition and signaling via the ubiquitin-proteasome system
  publication-title: Nat. Neurosci.
  doi: 10.1038/nn1013
– volume: 293
  start-page: 1074
  year: 2001
  ident: 10.1016/j.pneurobio.2004.05.005_bib142
  article-title: Translating the histone code
  publication-title: Science
  doi: 10.1126/science.1063127
– volume: 3
  start-page: E232
  year: 2001
  ident: 10.1016/j.pneurobio.2004.05.005_bib191
  article-title: Ubiquitination, proteasomes and GABA(A) receptors
  publication-title: Nat. Cell Biol.
  doi: 10.1038/ncb1001-e232
– volume: 15
  start-page: 2069
  year: 1996
  ident: 10.1016/j.pneurobio.2004.05.005_bib27
  article-title: Degradation of subunits of the Sec61p complex, an integral component of the ER membrane, by the ubiquitin-proteasome pathway
  publication-title: EMBO J.
  doi: 10.1002/j.1460-2075.1996.tb00560.x
– volume: 299
  start-page: 256
  year: 2003
  ident: 10.1016/j.pneurobio.2004.05.005_bib32
  article-title: Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism
  publication-title: Science
  doi: 10.1126/science.1077209
– volume: 384
  start-page: 432
  year: 1996
  ident: 10.1016/j.pneurobio.2004.05.005_bib347
  article-title: Sec61-mediated transfer of a membrane protein from the endoplasmic reticulum to the proteasome for destruction
  publication-title: Nature
  doi: 10.1038/384432a0
– volume: 17
  start-page: 2208
  year: 1998
  ident: 10.1016/j.pneurobio.2004.05.005_bib180
  article-title: A novel protein modification pathway related to the ubiquitin system
  publication-title: EMBO J.
  doi: 10.1093/emboj/17.8.2208
– volume: 228
  start-page: 517
  year: 1996
  ident: 10.1016/j.pneurobio.2004.05.005_bib311
  article-title: Specific developmental changes in the regulatory subunits of the 26 S proteasome in intersegmental muscles preceding eclosion in Maduca sexta
  publication-title: Biochem. Biophys. Res. Commun.
  doi: 10.1006/bbrc.1996.1692
– volume: 277
  start-page: 13935
  year: 2002
  ident: 10.1016/j.pneurobio.2004.05.005_bib74
  article-title: Polyglutamine expansion, protein aggregation, proteasome activity, and neural survival
  publication-title: J. Biol. Chem.
  doi: 10.1074/jbc.M107706200
– ident: 10.1016/j.pneurobio.2004.05.005_bib101
  doi: 10.1074/jbc.M308947200
– volume: 23
  start-page: 244
  year: 1998
  ident: 10.1016/j.pneurobio.2004.05.005_bib84
  article-title: Unified nomenclature for subunits of the S. cerevisiae proteasome regulatory particle
  publication-title: Trends Biochem. Sci.
  doi: 10.1016/S0968-0004(98)01222-5
– volume: 75
  start-page: 436
  year: 2000
  ident: 10.1016/j.pneurobio.2004.05.005_bib156
  article-title: Impaired proteasome function in Alzheimer’s disease
  publication-title: J. Neurochem.
  doi: 10.1046/j.1471-4159.2000.0750436.x
– volume: 13
  start-page: 286
  year: 2003
  ident: 10.1016/j.pneurobio.2004.05.005_bib77
  article-title: The staufen/pumilio pathway is involved in Drosophila long-term memory
  publication-title: Curr. Biol.
  doi: 10.1016/S0960-9822(03)00064-2
– volume: 91
  start-page: 927
  year: 1997
  ident: 10.1016/j.pneurobio.2004.05.005_bib197
  article-title: Synapse-specific, long-term facilitation of aplysia sensory to motor synapses: a function for local protein synthesis in memory storage
  publication-title: Cell
  doi: 10.1016/S0092-8674(00)80484-5
– volume: 15
  start-page: 74
  year: 1997
  ident: 10.1016/j.pneurobio.2004.05.005_bib203
  article-title: De novo truncating mutations in E6-AP ubiquitin-protein ligase gene (UBE3A) in Angelman syndrome
  publication-title: Nat. Genet.
  doi: 10.1038/ng0197-74
– volume: 388
  start-page: 891
  year: 1997
  ident: 10.1016/j.pneurobio.2004.05.005_bib256
  article-title: Mutant analysis links the translocon and BiP to retrograde protein transport for ER degradation
  publication-title: Nature
  doi: 10.1038/42276
– volume: 6
  start-page: 127
  year: 1991
  ident: 10.1016/j.pneurobio.2004.05.005_bib221
  article-title: Visuospatial cognition in Huntington’s disease
  publication-title: Mov. Disord.
  doi: 10.1002/mds.870060207
– volume: 90
  start-page: 7436
  year: 1993
  ident: 10.1016/j.pneurobio.2004.05.005_bib116
  article-title: Regulatory subunits of the cAMP-dependent protein kinases are degraded after conjugation to ubiquitin: a molecular mechanism underlying long-term synaptic plasticity
  publication-title: Proc. Natl. Acad. Sci. U.S.A.
  doi: 10.1073/pnas.90.16.7436
– volume: 394
  start-page: 793
  year: 1998
  ident: 10.1016/j.pneurobio.2004.05.005_bib48
  article-title: Epsin is an EH-domain-binding protein implicated in clathrin-mediated endocytosis
  publication-title: Nature
  doi: 10.1038/28660
– volume: 28
  start-page: 189
  year: 2003
  ident: 10.1016/j.pneurobio.2004.05.005_bib11
  article-title: Orchestrating nuclear functions: ubiquitin sets the rhythm
  publication-title: Trends Biochem. Sci.
  doi: 10.1016/S0968-0004(03)00055-0
– volume: 2
  start-page: E153
  year: 2000
  ident: 10.1016/j.pneurobio.2004.05.005_bib127
  article-title: Evolution and function of ubiquitin-like protein-conjugating systems
  publication-title: Nature Cell Biol.
  doi: 10.1038/35019643
– volume: 416
  start-page: 345
  year: 2002
  ident: 10.1016/j.pneurobio.2004.05.005_bib179
  article-title: TNF-RII and c-IAP1 mediate ubiquitination and degradation of TRAF2
  publication-title: Nature
  doi: 10.1038/416345a
– volume: 276
  start-page: 381
  year: 2001
  ident: 10.1016/j.pneurobio.2004.05.005_bib360
  article-title: The proteasome regulates receptor-mediated endocytosis of interleukin-2
  publication-title: J. Biol. Chem.
  doi: 10.1074/jbc.M007991200
– volume: 414
  start-page: 514
  year: 2001
  ident: 10.1016/j.pneurobio.2004.05.005_bib232
  article-title: Multisite phosphorylation of a CDK inhibitor sets a threshold for the onset of DNA replication
  publication-title: Nature
  doi: 10.1038/35107009
– volume: 21
  start-page: 4796
  year: 2002
  ident: 10.1016/j.pneurobio.2004.05.005_bib350
  article-title: Sprouty2 attenuates epidermal growth factor receptor ubiquitylation and endocytosis, and consequently enhances Ras/ERK signalling
  publication-title: EMBO J.
  doi: 10.1093/emboj/cdf493
– volume: 405
  start-page: 579
  year: 2000
  ident: 10.1016/j.pneurobio.2004.05.005_bib320
  article-title: Peptides accelerate their uptake by activating ubiquitin-dependent proteolytic pathway
  publication-title: Nature
  doi: 10.1038/35014629
– volume: 28
  start-page: 295
  year: 1999
  ident: 10.1016/j.pneurobio.2004.05.005_bib30
  article-title: The proteasome
  publication-title: Annu. Rev. Biophys. Biomol. Struct.
  doi: 10.1146/annurev.biophys.28.1.295
– volume: 16
  start-page: 6325
  year: 1997
  ident: 10.1016/j.pneurobio.2004.05.005_bib306
  article-title: Regulation of stability and function of the epithelial Na+ channel (ENaC) by ubiquitination
  publication-title: EMBO J.
  doi: 10.1093/emboj/16.21.6325
– ident: 10.1016/j.pneurobio.2004.05.005_bib199
  doi: 10.1074/jbc.M308285200
– volume: 273
  start-page: 24057
  year: 1998
  ident: 10.1016/j.pneurobio.2004.05.005_bib248
  article-title: p35, the neuronal-specific activator of cyclin-dependent kinase 5 (Cdk5) is degraded by the ubiquitin-proteasome pathway
  publication-title: J. Biol. Chem.
  doi: 10.1074/jbc.273.37.24057
– ident: 10.1016/j.pneurobio.2004.05.005_bib285
  doi: 10.1126/stke.2003.190.pe26
– volume: 274
  start-page: 27299
  year: 1999
  ident: 10.1016/j.pneurobio.2004.05.005_bib202
  article-title: E2/E3-mediated assembly of lysine 29-linked polyubiquitin chains
  publication-title: J. Biol. Chem.
  doi: 10.1074/jbc.274.38.27299
– volume: 34
  start-page: 14535
  year: 1995
  ident: 10.1016/j.pneurobio.2004.05.005_bib345
  article-title: Metabolism of the polyubiquitin degradation signal: structure, mechanism, and role of isopeptidase T
  publication-title: Biochemistry
  doi: 10.1021/bi00044a032
– volume: 17
  start-page: 669
  year: 1996
  ident: 10.1016/j.pneurobio.2004.05.005_bib62
  article-title: Genetic dissection of structural and functional components of synaptic plasticity. III. CREB is necessary for presynaptic functional plasticity
  publication-title: Neuron
  doi: 10.1016/S0896-6273(00)80199-3
– volume: 96
  start-page: 645
  year: 1999
  ident: 10.1016/j.pneurobio.2004.05.005_bib130
  article-title: Noncanonical MMS2-encoded ubiquitin-conjugating enzyme functions in assembly of novel polyubiquitin chains for DNA repair
  publication-title: Cell
  doi: 10.1016/S0092-8674(00)80575-9
– volume: 466
  start-page: 377
  year: 2000
  ident: 10.1016/j.pneurobio.2004.05.005_bib3
  article-title: Regulation of the cardiac voltage-gated Na+ channel (H1) by the ubiquitin-protein ligase Nedd4
  publication-title: FEBS Lett.
  doi: 10.1016/S0014-5793(00)01098-X
– volume: 28
  start-page: 245
  year: 2000
  ident: 10.1016/j.pneurobio.2004.05.005_bib35
  article-title: Increasing numbers of synaptic puncta during late-phase LTP: N-cadherin is synthesized, recruited to synaptic sites, and required for potentiation
  publication-title: Neuron
  doi: 10.1016/S0896-6273(00)00100-8
– volume: 293
  start-page: 1651
  year: 2001
  ident: 10.1016/j.pneurobio.2004.05.005_bib276
  article-title: Regulation of transcriptional activation domain function by ubiquitin
  publication-title: Science
  doi: 10.1126/science.1062079
– volume: 5
  start-page: 123
  year: 1985
  ident: 10.1016/j.pneurobio.2004.05.005_bib1
  article-title: Activity-dependent presynaptic facilitation: an associative mechanism in Aplysia
  publication-title: Cell. Mol. Neurobiol.
  doi: 10.1007/BF00711089
– volume: 5
  start-page: D837
  year: 2000
  ident: 10.1016/j.pneurobio.2004.05.005_bib204
  article-title: Proteasomes in the archaea: from structure to function
  publication-title: Front Biosci.
  doi: 10.2741/furlow
– volume: 392
  start-page: 605
  year: 1998
  ident: 10.1016/j.pneurobio.2004.05.005_bib161
  article-title: Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
  publication-title: Nature
  doi: 10.1038/33416
– volume: 4
  start-page: 301
  year: 2003
  ident: 10.1016/j.pneurobio.2004.05.005_bib273
  article-title: Parkin binds the Rpn10 subunit of 26S proteasomes through its ubiquitin-like domain
  publication-title: EMBO Rep.
  doi: 10.1038/sj.embor.embor764
– volume: 17
  start-page: 1336
  year: 1998
  ident: 10.1016/j.pneurobio.2004.05.005_bib297
  article-title: The Polo-like kinase Cdc5p and the WD-repeat protein Cdc20p/fizzy are regulators and substrates of the anaphase promoting complex in Saccharomyces cerevisiae
  publication-title: EMBO J.
  doi: 10.1093/emboj/17.5.1336
– volume: 83
  start-page: 129
  year: 1995
  ident: 10.1016/j.pneurobio.2004.05.005_bib141
  article-title: Multiple proteolytic systems, including the proteasome, contribute to CFTR processing
  publication-title: Cell
  doi: 10.1016/0092-8674(95)90241-4
– volume: 290
  start-page: 1574
  year: 2000
  ident: 10.1016/j.pneurobio.2004.05.005_bib212
  article-title: Beta-arrestin 2: a receptor-regulated MAPK scaffold for the activation of JNK3
  publication-title: Science
  doi: 10.1126/science.290.5496.1574
– volume: 274
  start-page: 1199
  year: 1996
  ident: 10.1016/j.pneurobio.2004.05.005_bib251
  article-title: Identification of BIME as a subunit of the anaphase-promoting complex
  publication-title: Science
  doi: 10.1126/science.274.5290.1199
– volume: 275
  start-page: 1575
  year: 2000
  ident: 10.1016/j.pneurobio.2004.05.005_bib329
  article-title: Endocytosis and degradation of the growth hormone receptor are proteasome-dependent
  publication-title: J. Biol. Chem.
  doi: 10.1074/jbc.275.3.1575
– volume: 292
  start-page: 1552
  year: 2001
  ident: 10.1016/j.pneurobio.2004.05.005_bib24
  article-title: Impairment of the ubiquitin system by protein aggregation
  publication-title: Science
  doi: 10.1126/science.292.5521.1552
– volume: 99
  start-page: 1842
  year: 2002
  ident: 10.1016/j.pneurobio.2004.05.005_bib169
  article-title: Ubiquitin-dependent mechanism regulates rapid turnover of AU-rich cytokine mRNAs
  publication-title: Proc. Natl. Acad. Sci. U.S.A.
  doi: 10.1073/pnas.042575699
– volume: 253
  start-page: 466
  year: 1986
  ident: 10.1016/j.pneurobio.2004.05.005_bib70
  article-title: Changes in the numerical density of synaptic contacts with long-term potentiation in the hippocampal dentate gyrus
  publication-title: J. Comp. Neurol.
  doi: 10.1002/cne.902530404
– volume: 1
  start-page: 371
  year: 1998
  ident: 10.1016/j.pneurobio.2004.05.005_bib164
  article-title: PKA and MPF-activated polo-like kinase regulate anaphase-promoting complex activity and mitosis progression
  publication-title: Mol. Cell
  doi: 10.1016/S1097-2765(00)80037-4
– volume: 220
  start-page: 91
  year: 1983
  ident: 10.1016/j.pneurobio.2004.05.005_bib12
  article-title: Morphological basis of long-term habituation and sensitization in Aplysia
  publication-title: Science
  doi: 10.1126/science.6828885
– volume: 33
  start-page: 332
  year: 1998
  ident: 10.1016/j.pneurobio.2004.05.005_bib60
  article-title: Deubiquitinating enzymes: a new class of biological regulators
  publication-title: Crit. Rev. Biochem. Mol. Biol.
– volume: 26
  start-page: 347
  year: 2001
  ident: 10.1016/j.pneurobio.2004.05.005_bib131
  article-title: A ubiquitin-interacting motif conserved in components of the proteasomal and lysosomal degradation systems
  publication-title: Trends Biochem. Sci.
  doi: 10.1016/S0968-0004(01)01835-7
– volume: 102
  start-page: 549
  year: 2000
  ident: 10.1016/j.pneurobio.2004.05.005_bib146
  article-title: RING finger proteins: mediators of ubiquitin ligase activity
  publication-title: Cell
  doi: 10.1016/S0092-8674(00)00077-5
– volume: 38
  start-page: 871
  year: 2003
  ident: 10.1016/j.pneurobio.2004.05.005_bib340
  article-title: Axon pruning during Drosophila metamorphosis: evidence for local degeneration and requirement of the ubiquitin-proteasome system
  publication-title: Neuron
  doi: 10.1016/S0896-6273(03)00295-2
– volume: 8
  start-page: 825
  year: 1997
  ident: 10.1016/j.pneurobio.2004.05.005_bib8
  article-title: Isolation and molecular characterization of mRNA transport mutants in Schizosaccharomyces pombe
  publication-title: Mol. Biol. Cell
  doi: 10.1091/mbc.8.5.825
– volume: 15
  start-page: 1
  year: 1995
  ident: 10.1016/j.pneurobio.2004.05.005_bib246
  article-title: Morphological analysis of dendritic spine development in primary cultures of hippocampal neurons
  publication-title: J. Neurosci.
  doi: 10.1523/JNEUROSCI.15-01-00001.1995
– volume: 89
  start-page: 115
  year: 1997
  ident: 10.1016/j.pneurobio.2004.05.005_bib117
  article-title: Ubiquitin C-terminal hydrolase is an immediate-early gene essential for long-term facilitation in Aplysia
  publication-title: Cell
  doi: 10.1016/S0092-8674(00)80188-9
– volume: 278
  start-page: 460
  year: 1997
  ident: 10.1016/j.pneurobio.2004.05.005_bib335
  article-title: CDC20 and CDH1: a family of substrate-specific activators of APC-dependent proteolysis
  publication-title: Science
  doi: 10.1126/science.278.5337.460
– volume: 40
  start-page: 595
  year: 2003
  ident: 10.1016/j.pneurobio.2004.05.005_bib54
  article-title: Ubiquitination regulates PSD-95 degradation and AMPA receptor surface expression
  publication-title: Neuron
  doi: 10.1016/S0896-6273(03)00687-1
– volume: 15
  start-page: 5268
  year: 1996
  ident: 10.1016/j.pneurobio.2004.05.005_bib354
  article-title: The role of proteolysis in cell cycle progression in Schizosaccharomyces pombe
  publication-title: EMBO J.
  doi: 10.1002/j.1460-2075.1996.tb00912.x
– volume: 19
  start-page: 331
  year: 1967
  ident: 10.1016/j.pneurobio.2004.05.005_bib100
  article-title: The effect of visual deprivation on cortical neurons: a Golgi study
  publication-title: Exp. Neurol.
  doi: 10.1016/0014-4886(67)90029-5
– volume: 1
  start-page: 565
  year: 1998
  ident: 10.1016/j.pneurobio.2004.05.005_bib195
  article-title: A novel human WD protein, human β-TrCP, that interacts with HIV-1 Vpu, connects CD4 to the ER degradation pathway through an F-box motif
  publication-title: Mol. Cell
  doi: 10.1016/S1097-2765(00)80056-8
– volume: 21
  start-page: 208
  year: 1996
  ident: 10.1016/j.pneurobio.2004.05.005_bib281
  article-title: Does this have a familiar RING?
  publication-title: Trends Biochem. Sci.
  doi: 10.1016/0968-0004(96)10036-0
– volume: 361
  start-page: 453
  year: 1993
  ident: 10.1016/j.pneurobio.2004.05.005_bib263
  article-title: Tissue-plasminogen activator is induced as an immediate-early gene during seizure, kindling and long-term potentiation
  publication-title: Nature
  doi: 10.1038/361453a0
– volume: 61
  start-page: 761
  year: 1992
  ident: 10.1016/j.pneurobio.2004.05.005_bib121
  article-title: The ubiquitin system for protein degradation
  publication-title: Annu. Rev. Biochem.
  doi: 10.1146/annurev.bi.61.070192.003553
– volume: 85
  start-page: 115
  year: 2003
  ident: 10.1016/j.pneurobio.2004.05.005_bib155
  article-title: Proteasome inhibition by paired helical filament-tau in brains of patients with Alzheimer’s disease
  publication-title: J. Neurochem.
  doi: 10.1046/j.1471-4159.2003.01642.x
– volume: 267
  start-page: 6429
  year: 1992
  ident: 10.1016/j.pneurobio.2004.05.005_bib222
  article-title: Ligand-induced polyubiquitination of the platelet-derived growth factor β-receptor
  publication-title: J. Biol. Chem.
  doi: 10.1016/S0021-9258(18)42714-7
– volume: 7
  start-page: 1250
  year: 1998
  ident: 10.1016/j.pneurobio.2004.05.005_bib7
  article-title: Homologues of 26S proteasome subunits are regulators of transcription and translation
  publication-title: Protein Sci.
  doi: 10.1002/pro.5560070521
– volume: 73
  start-page: 19
  year: 1979
  ident: 10.1016/j.pneurobio.2004.05.005_bib148
  article-title: Cellular insights into behavior and learning
  publication-title: Harvey Lect.
– volume: 14
  start-page: 1820
  year: 2001
  ident: 10.1016/j.pneurobio.2004.05.005_bib187
  article-title: The ubiquitin-proteasome cascade is required for mammalian long-term memory formation
  publication-title: Eur. J. Neurosci.
  doi: 10.1046/j.0953-816x.2001.01806.x
– volume: 3
  start-page: 932
  year: 2002
  ident: 10.1016/j.pneurobio.2004.05.005_bib189
  article-title: Pathogenesis of Parkinson’s disease: dopamine, vesicles and alpha-synuclein
  publication-title: Nat. Rev. Neurosci.
  doi: 10.1038/nrn983
– volume: 6
  start-page: 244
  year: 2004
  ident: 10.1016/j.pneurobio.2004.05.005_bib262
  article-title: Interactions of GGA3 with the ubiquitin sorting machinery
  publication-title: Nat. Cell Biol.
  doi: 10.1038/ncb1106
– volume: 96
  start-page: 11317
  year: 1999
  ident: 10.1016/j.pneurobio.2004.05.005_bib95
  article-title: Expression of the CDH1-associated form of the anaphase-promoting complex in postmitotic neurons
  publication-title: Proc. Natl. Acad. Sci. U.S.A.
  doi: 10.1073/pnas.96.20.11317
– volume: 298
  start-page: 608
  year: 2002
  ident: 10.1016/j.pneurobio.2004.05.005_bib57
  article-title: Role of predicted metalloprotease motif of Jab1/Csn5 in cleavage of Nedd8 from Cul1
  publication-title: Science
  doi: 10.1126/science.1075901
– volume: 6
  start-page: 252
  year: 2004
  ident: 10.1016/j.pneurobio.2004.05.005_bib289
  article-title: GGA proteins bind ubiquitin to facilitate sorting at the trans-Golgi network
  publication-title: Nat. Cell Biol.
  doi: 10.1038/ncb1107
– volume: 35
  start-page: 447
  year: 2002
  ident: 10.1016/j.pneurobio.2004.05.005_bib229
  article-title: Drosophila Nedd4, a ubiquitin ligase, is recruited by commissureless to control cell surface levels of the roundabout receptor
  publication-title: Neuron
  doi: 10.1016/S0896-6273(02)00795-X
SSID ssj0006303
Score 2.1704805
SecondaryResourceType review_article
Snippet A proteolytic pathway in which attachment of a small protein, ubiquitin, marks the substrates for degradation by a multi-subunit complex called the proteasome...
SourceID proquest
pubmed
crossref
SourceType Aggregation Database
Index Database
Enrichment Source
StartPage 311
SubjectTerms Animals
Humans
Neuronal Plasticity - physiology
Proteasome Endopeptidase Complex - physiology
Protein Denaturation
Synapses - enzymology
Synapses - metabolism
Synapses - physiology
Ubiquitin - physiology
Title Ubiquitin-proteasome-mediated local protein degradation and synaptic plasticity
URI https://www.ncbi.nlm.nih.gov/pubmed/15312912
https://www.proquest.com/docview/18036678
https://www.proquest.com/docview/66794726
Volume 73
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1Lb9QwELZge-GCgPJYnj4gLiiVEzuxc1xVrSq0tBXalfZm2YldtmqzSzd7KL-esZ1HI1oKXKIoiWPLXzL-bM98g9BHYctU5_CnAfcoIqZjFgmViohSK7KSqphbFyj89Tg7mrMvi3TRZzz10SW13it-3hpX8j-owjXA1UXJ_gOy3UvhApwDvnAEhOH4VxjP9fLHdlkvq8jLLajN6tJEPhbE8Ug_TH32d7zL69mVCgmU_IbB5rpSa6fWugb-7Fyr68EG76nz23JWEIp6zctGralfOz0Lgr2TzXcXLTFYPWCd71oXNeWWE4gYWMSQXKRBPr1h3mgwjL-Z3bACcL63bhvkJ95eEpWk_UjT7q4fn8jD-XQqZweL2UO0kwDDT0ZoZ7L_bXraDaMZJSG3ddPAgXPerRUNqcUd8wXPG2ZP0OOG8ONJQO8pemCqZ2h3Uql6dXmNP2Hvguu7dhed_BFQ7AHFDaD4BqAYAMUtoLgH9DmaHx7M9o-iJuNFVACxqiMrVEGsIZqlNiOlViUX1lLDRanhZyKmoCYzGYV5ni6J4jAb5sYCaVPcAJNU9AUaVavKvEI4J5zbxOkBGs3iXAkmCkryUgPlBlZajlHWdpYsGjl4l5XkQrZ-f-ey62WXrJRJkkro5TEiXcF1UES5v8iHFg0J1sttSanKrLYbGQtgUMCX7n4C7uaMJ9kYvQww9pXC8JHkcfL63rJv0KP-23-LRvXV1rwDLlnr981X9ws763ug
linkProvider Elsevier
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Ubiquitin-proteasome-mediated+local+protein+degradation+and+synaptic+plasticity&rft.jtitle=Progress+in+neurobiology&rft.au=Hegde%2C+Ashok+N&rft.date=2004-08-01&rft.issn=0301-0082&rft.volume=73&rft.issue=5&rft.spage=311&rft_id=info:doi/10.1016%2Fj.pneurobio.2004.05.005&rft.externalDBID=NO_FULL_TEXT
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0301-0082&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0301-0082&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0301-0082&client=summon