Spinal and Paraspinal Plexiform Neurofibromas in Patients with Neurofibromatosis Type 1: A Novel Scoring System for Radiological-Clinical Correlation

• Published in: American journal of neuroradiology : AJNR Vol. 38; no. 10; pp. 1869 - 1875
• Main Authors: Mauda-Havakuk, M, Shofty, B, Ben-Shachar, S, Ben-Sira, L, Constantini, S, Bokstein, F
• Format: Journal Article
• Language: English
• Published: United States American Society of Neuroradiology 01.10.2017
• Subjects: Adult; Aged; Classification; Cohort Studies; Female; Genetic disorders; Humans; Lesions; Lumbar region; Lumbosacral Region - pathology; Male; Mathematical analysis; Middle Aged; Morbidity; Neurofibroma, Plexiform - complications; Neurofibroma, Plexiform - diagnostic imaging; Neurofibroma, Plexiform - pathology; Neurofibromatosis; Neurofibromatosis 1 - complications; Neurofibromatosis 1 - diagnostic imaging; Neurofibromatosis 1 - pathology; Pain; Patients; Recklinghausen's disease; Risk; Spinal Diseases - complications; Spinal Diseases - diagnostic imaging; Spinal Diseases - pathology; Spine; Tumors

Neurofibromatosis type 1 is a common tumor predisposition syndrome. The aim of this study was to characterize the radiologic presentation of patients with neurofibromatosis type 1 with widespread spinal disease and to correlate it to clinical presentation and outcome. We conducted a historical cohor...