Reconstruction of metatarsal bone after giant cell tumor resection with no vascularized fibular graft in a pediatric patient: Case report and review of literature

The Giant Cell tumor (GCT) is a benign, locally aggressive lesion that cause bone destruction and shows a malignant potential. It is a relatively common skeletal tumor that is therefore typically seen in young adults. Few cases are described in literature of GCT in the immature skeleton, and the met...

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Published inFrontiers in pediatrics Vol. 10
Main Authors Florio, M., Careri, S., Zoccali, C., Aulisa, A. G., Falciglia, F., Toniolo, R. M., Giordano, M.
Format Journal Article
LanguageEnglish
Published Frontiers Media S.A 12.10.2022
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Abstract The Giant Cell tumor (GCT) is a benign, locally aggressive lesion that cause bone destruction and shows a malignant potential. It is a relatively common skeletal tumor that is therefore typically seen in young adults. Few cases are described in literature of GCT in the immature skeleton, and the metatarsal is an unusual location for a primary bone GCT, especially in pediatric age. Therefore, there are very few data reported regarding the management protocol of GCT in metatarsal bones. We report a case about the use of no vascularized fibular graft for an original Y-shaped reconstruction of the metatarsal bone after Giant Cell Tumor resection in a 9 years-old patient, and performed a literature review about metatarsal bone reconstruction in skeletally immature patient.
AbstractList The Giant Cell tumor (GCT) is a benign, locally aggressive lesion that cause bone destruction and shows a malignant potential. It is a relatively common skeletal tumor that is therefore typically seen in young adults. Few cases are described in literature of GCT in the immature skeleton, and the metatarsal is an unusual location for a primary bone GCT, especially in pediatric age. Therefore, there are very few data reported regarding the management protocol of GCT in metatarsal bones. We report a case about the use of no vascularized fibular graft for an original Y-shaped reconstruction of the metatarsal bone after Giant Cell Tumor resection in a 9 years-old patient, and performed a literature review about metatarsal bone reconstruction in skeletally immature patient.
Author Careri, S.
Aulisa, A. G.
Toniolo, R. M.
Giordano, M.
Zoccali, C.
Falciglia, F.
Florio, M.
AuthorAffiliation 1 Department of Surgery and Transplant, Division of Traumatology , Bambino Gesu’ Children Hospital (IRCCS) , Rome , Italy
3 University of Cassino and Southern Lazio , Cassino , Italy
2 Department of Human Anatomy, Histology, Forensic Medicine, Orthopedics , Sapienza University , Rome , Italy
AuthorAffiliation_xml – name: 3 University of Cassino and Southern Lazio , Cassino , Italy
– name: 2 Department of Human Anatomy, Histology, Forensic Medicine, Orthopedics , Sapienza University , Rome , Italy
– name: 1 Department of Surgery and Transplant, Division of Traumatology , Bambino Gesu’ Children Hospital (IRCCS) , Rome , Italy
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Cites_doi 10.3113/FAI.2008.0097
10.1007/BF00206148
10.1302/0301-620X.80B1.0800043
10.1007/s002640050057
10.1097/00003086-198603000-00003
10.2106/00004623-198365040-00009
10.5704/MOJ.1311.001
10.1016/0165-4608(92)90125-R
10.1002/(SICI)1097-0142(20000501)88:9%3C2022::AID-CNCR6%3E3.0.CO;2-Y
10.1302/0301-620X.76B6.7983128
10.1016/j.ocl.2005.08.005
10.1148/radiol.2451031776
10.1634/theoncologist.2014-0267
10.1007/BF00209107
10.26355/eurrev_201904_17495
10.2106/00004623-198769010-00018
10.5005/jp-journals-10080-1462
10.1016/S0033-8389(22)02859-7
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Copyright 2022 Florio, Careri, Zoccali, Aulisa, Falciglia, Toniolo and Giordano. 2022 Florio, Careri, Zoccali, Aulisa, Falciglia, Toniolo and Giordano
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Notes Specialty Section: This article was submitted to Pediatric Orthopedics, a section of the journal Frontiers in Pediatrics
Edited by: Marco Rainer Kesting, University Hospital Erlangen, Germany
Reviewed by: Sherif Kheir, Ain Shams University, Egypt Francesco Liuzza, Agostino Gemelli University Polyclinic (IRCCS), Italy
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References Campanacci (B15) 1987; 69
Rengsen (B19) 2013; 7
Lausten (B16) 1996; 20
Guzzanti (B20) 1994; 76
Enneking (B17) 1986; 204
Siebenrock (B1) 1998; 80
Mirra (B3) 1989
Hoeffel (B4) 1996; 63
Picci (B9) 1983; 65
Bridge (B5) 1992; 58
Schutte (B10) 1993; 22
Biscaglia (B14) 2000; 88
Manaster (B2) 1993; 31
Turcotte (B6) 2006; 37
Wang (B13) 2008; 29
Sheridan (B18) 2020; 15
Ly (B11) 2007; 245
Careri (B21) 2019; 23
Aaron (B12) 1993; 22
Cavanna (B7) 2014; 19
Huvos (B8) 1922
References_xml – volume: 29
  start-page: 97
  year: 2008
  ident: B13
  article-title: Allograft reconstruction of a large giant cell tumor of the first metatarsal: a case report
  publication-title: Foot Ankle Int
  doi: 10.3113/FAI.2008.0097
  contributor:
    fullname: Wang
– volume: 22
  start-page: 173
  year: 1993
  ident: B10
  article-title: Giant cell tumor in children and adolescents
  publication-title: Skeletal Radiol
  doi: 10.1007/BF00206148
  contributor:
    fullname: Schutte
– volume: 80
  start-page: 43
  year: 1998
  ident: B1
  article-title: Giant-cell tumour of bone metastasising to the lungs. A long-term follow-up
  publication-title: J Bone Joint Surg Br
  doi: 10.1302/0301-620X.80B1.0800043
  contributor:
    fullname: Siebenrock
– volume: 20
  start-page: 172
  year: 1996
  ident: B16
  article-title: Local recurrences in giant cell tumour of bone. Long-term follow up of 31 cases
  publication-title: Int Orthop
  doi: 10.1007/s002640050057
  contributor:
    fullname: Lausten
– volume: 204
  start-page: 9
  year: 1986
  ident: B17
  article-title: A system of staging musculoskeletal neoplasm
  publication-title: Clin Orthop Relat Res
  doi: 10.1097/00003086-198603000-00003
  contributor:
    fullname: Enneking
– volume: 65
  start-page: 486
  year: 1983
  ident: B9
  article-title: Giant-cell tumor of bone in skeletally immature patients
  publication-title: J Bone Joint Surg Am
  doi: 10.2106/00004623-198365040-00009
  contributor:
    fullname: Picci
– volume: 7
  start-page: 15
  year: 2013
  ident: B19
  article-title: Reconstruction of the second metatarsal with non-vascularized fibular graft following en-bloc resection for giant celll tumour: a case report
  publication-title: Malays Orthop J
  doi: 10.5704/MOJ.1311.001
  contributor:
    fullname: Rengsen
– volume: 58
  start-page: 2
  year: 1992
  ident: B5
  article-title: Giant cell tumor of bone. Chromosomal analysis of 48 specimens and review of the literature
  publication-title: Cancer Genet Cytogenet
  doi: 10.1016/0165-4608(92)90125-R
  contributor:
    fullname: Bridge
– volume: 88
  start-page: 2022
  year: 2000
  ident: B14
  article-title: Giant cell tumor of the bones of the hand and foot
  publication-title: Cancer
  doi: 10.1002/(SICI)1097-0142(20000501)88:9%3C2022::AID-CNCR6%3E3.0.CO;2-Y
  contributor:
    fullname: Biscaglia
– volume: 76
  start-page: 960
  year: 1994
  ident: B20
  article-title: The effect of intra-articular ACL reconstruction on the growth plates of rabbits
  publication-title: J Bone Joint Surg Br
  doi: 10.1302/0301-620X.76B6.7983128
  contributor:
    fullname: Guzzanti
– volume: 37
  start-page: 35
  year: 2006
  ident: B6
  article-title: Giant cell tumor of bone
  publication-title: Orthop Clin North Am
  doi: 10.1016/j.ocl.2005.08.005
  contributor:
    fullname: Turcotte
– volume-title: Bone tumors: Clinical, radiologic and pathologic correlations
  year: 1989
  ident: B3
  contributor:
    fullname: Mirra
– volume: 245
  start-page: 288
  year: 2007
  ident: B11
  article-title: Case 122: giant cell tumor of the second metatarsal
  publication-title: Radiology
  doi: 10.1148/radiol.2451031776
  contributor:
    fullname: Ly
– volume: 19
  start-page: 1207
  year: 2014
  ident: B7
  article-title: Giant cell tumor of bone
  publication-title: Oncologist
  doi: 10.1634/theoncologist.2014-0267
  contributor:
    fullname: Cavanna
– start-page: 1106
  volume-title: Bone tumors: Diagnosis, treatment,and prognosisLancet
  year: 1922
  ident: B8
  article-title: The histogenesis of myeloid sarcoma
  contributor:
    fullname: Huvos
– volume: 22
  start-page: 543
  year: 1993
  ident: B12
  article-title: Case report 810: giant cell tumor of the first metatarsal
  publication-title: Skeletal Radiol
  doi: 10.1007/BF00209107
  contributor:
    fullname: Aaron
– volume: 23
  start-page: 210
  year: 2019
  ident: B21
  article-title: Masquelet technique and osteomyelitis: innovations and literature review
  publication-title: Eur Rev Med Pharmacol Sci
  doi: 10.26355/eurrev_201904_17495
  contributor:
    fullname: Careri
– volume: 69
  start-page: 106
  year: 1987
  ident: B15
  article-title: Giant cell tumor of bone
  publication-title: J Bone Joint Surg Am
  doi: 10.2106/00004623-198769010-00018
  contributor:
    fullname: Campanacci
– volume: 63
  start-page: 618
  year: 1996
  ident: B4
  article-title: Giant cell tumor of bone in children and adolescents
  publication-title: Rev Rhum Engl Ed
  contributor:
    fullname: Hoeffel
– volume: 15
  start-page: 84
  year: 2020
  ident: B18
  article-title: Non-vascularised fibular autograft for reconstruction of paediatric bone defects: an analysis of 10 cases
  publication-title: Strateg Trauma Limb Reconstr
  doi: 10.5005/jp-journals-10080-1462
  contributor:
    fullname: Sheridan
– volume: 31
  start-page: 299
  year: 1993
  ident: B2
  article-title: Giant cell tumors of bone
  publication-title: Radiol Clin North Am
  doi: 10.1016/S0033-8389(22)02859-7
  contributor:
    fullname: Manaster
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Snippet The Giant Cell tumor (GCT) is a benign, locally aggressive lesion that cause bone destruction and shows a malignant potential. It is a relatively common...
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SubjectTerms en-bloc resection
foot tumors
metacarpal replacement
non-vascularized fibular graft
pediatric giant cell tumor
Pediatrics
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Title Reconstruction of metatarsal bone after giant cell tumor resection with no vascularized fibular graft in a pediatric patient: Case report and review of literature
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