PROX1-mediated epigenetic silencing of SIRT3 contributes to proliferation and glucose metabolism in colorectal cancer - Gan, Lu; Li, Qingguo; Nie, Wei; Zhang, Yi; Jiang, Hesheng; Tan, Cong; Zhang, Long; Zhang, Jieyun; Li, Qian; Hou, Pengcong; Yuan, Yitao; Sun, Xun; et al. (International journal of biological sciences, 2023)
Keywords: Cancer; Cancer therapies; Cell growth; Cell Line, Tumor; Cell proliferation; Cell Proliferation - genetics; Chemotherapy; Colorectal cancer; Colorectal carcinoma; Colorectal Neoplasms - metabolism; Consortia; Epigenesis, Genetic - genetics; Epigenetics; Experiments; Gene expression; Gene Expression Regulation, Neoplastic - genetics; Genomes; Glucose; Glucose - metabolism; Glycolysis; Homeobox; Human subjects; Humans; Kinases; Medical prognosis; Metabolism; Metastasis; Online data bases; Prospero protein; Protein expression; Proteins; R&D; Research & development; Research Paper; Sirtuin 3 - metabolism; Tomography; Transcription Factors - metabolism; Tumors; United States--US; China; colorectal cancer; PROX1; aerobic glycolysis; prognosis; EZH2; SIRT3