Assessment of matrix metalloproteinase (MMP)-2, MMP-8, MMP-9, and their inhibitors, the tissue inhibitors of metalloproteinase (TIMP)-1 and TIMP-2 in obese children and adolescents

• Published in: Clinical biochemistry Vol. 42; no. 10; pp. 984 - 990
• Main Authors: Belo, Vanessa A., Souza-Costa, Debora C., Lana, Carla M., Caputo, Fabio L.D., Marcaccini, Andrea M., Gerlach, Raquel F., Bastos, Marcus G., Tanus-Santos, Jose E.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.07.2009
• Subjects: Adolescent; Adolescents; Child; Children; Demography; Female; Humans; Male; Matrix Metalloproteinase 2 - blood; Matrix Metalloproteinase 8 - blood; Matrix Metalloproteinase 9 - blood; Matrix Metalloproteinases - blood; Metalloproteinases; Obesity; Obesity - blood; Obesity - enzymology; Protein Precursors - blood; Sex Characteristics; TIMPs; Tissue Inhibitor of Metalloproteinase-1 - blood; Tissue Inhibitor of Metalloproteinase-2 - blood; Obesity; TIMPs; Children; Adolescents; Metalloproteinases

To compare the circulating levels of matrix metalloproteinase (MMP)-8, pro-MMP-2, pro-MMP-9, and total MMP-9, their endogenous inhibitors, the tissue inhibitors of metalloproteinases (TIMP)-1 and TIMP-2, and the MMP-8/TIMP-1, MMP-9/TIMP-1, and MMP-2/TIMP-2 ratios in normotensive obese children and a...