In Vitro Activities of Daptomycin, Linezolid, and Quinupristin-Dalfopristin against a Challenge Panel of Staphylococci and Enterococci, Including Vancomycin-Intermediate Staphylococcus aureus and Vancomycin-Resistant Enterococcus faecium

• Published in: Microbial drug resistance (Larchmont, N.Y.) Vol. 9; no. 4; pp. 389 - 393
• Main Authors: Jevitt, Laura A., Smith, Amanda J., Williams, Portia P., Raney, Patti M., McGowan, John E., Tenover, Fred C.
• Format: Journal Article
• Language: English
• Published: United States Mary Ann Liebert, Inc 01.12.2003
• Subjects: Acetamides - pharmacology; Anti-Bacterial Agents - pharmacology; Anti-Infective Agents - pharmacology; Antibiotic resistance; Antimicrobial agents; Daptomycin - pharmacology; Disease; Drug Therapy, Combination - pharmacology; Enterococcus faecium; Enterococcus faecium - drug effects; Genes, Bacterial - genetics; Linezolid; Methicillin Resistance; Microbial Sensitivity Tests; Oxazolidinones - pharmacology; Staphylococcus aureus; Staphylococcus aureus - drug effects; Staphylococcus aureus - genetics; Vancomycin Resistance - genetics; Virginiamycin - pharmacology

We assessed the in vitro activities of daptomycin, linezolid, and quinupristin-dalfopristin (QD) against a contemporary challenge panel of 88 staphylococcal and 90 enterococcal isolates. The staphylococci selected included vancomycin-intermediate Staphylococcus aureus (VISA), methicillin-resistant S...