A parameter study of pencil beam proton dose distributions for the treatment of ocular melanoma utilizing spot scanning
The results of Monte Carlo calculated dose distributions of proton treatment of ocular melanoma are presented. An efficient spot scanning method utilizing active energy modulation, which also minimizes the number of target spots was developed. We simulated various parameter values for the particle e...
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| Published in | Radiological physics and technology Vol. 3; no. 1; pp. 16 - 22 |
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| Main Authors | , , , , , , , , |
| Format | Journal Article |
| Language | English |
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Japan
Springer Japan
01.01.2010
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| Abstract | The results of Monte Carlo calculated dose distributions of proton treatment of ocular melanoma are presented. An efficient spot scanning method utilizing active energy modulation, which also minimizes the number of target spots was developed. We simulated various parameter values for the particle energy spread and the pencil beam diameter in order to determine values suitable for medical treatment. We found that a 2.5-mm-diameter proton beam with a 5% Gaussian energy spread was suitable for treatment of ocular melanoma while preserving vision for the typical case that we simulated. The energy spectra and the required proton current were also calculated and are reported. The results are intended to serve as a guideline for a new class of low-cost, compact accelerators. |
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| AbstractList | The results of Monte Carlo calculated dose distributions of proton treatment of ocular melanoma are presented. An efficient spot scanning method utilizing active energy modulation, which also minimizes the number of target spots was developed. We simulated various parameter values for the particle energy spread and the pencil beam diameter in order to determine values suitable for medical treatment. We found that a 2.5-mm-diameter proton beam with a 5% Gaussian energy spread was suitable for treatment of ocular melanoma while preserving vision for the typical case that we simulated. The energy spectra and the required proton current were also calculated and are reported. The results are intended to serve as a guideline for a new class of low-cost, compact accelerators. |
| Author | Ishikawa, Masayori Sutherland, Kenneth Bolton, Paul Miyajima, Satoshi Murakami, Masao Shirato, Hiroki Date, Hiroyuki Tajima, Toshiki Yamagiwa, Mitsuru |
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| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/20821097$$D View this record in MEDLINE/PubMed |
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| SubjectTerms | Eye Neoplasms - pathology Eye Neoplasms - radiotherapy Humans Imaging Lasers Medical and Radiation Physics Medicine Medicine & Public Health Melanoma - pathology Melanoma - radiotherapy Monte Carlo Method Nuclear Medicine Organs at Risk - radiation effects Protons - therapeutic use Radiation Dosage Radiology Radiotherapy Radiotherapy Dosage Tumor Burden |
| Title | A parameter study of pencil beam proton dose distributions for the treatment of ocular melanoma utilizing spot scanning |
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