Salvage Surgery for Esophageal Cancer: How to Improve Outcomes?

• Published in: Annals of surgical oncology Vol. 25; no. 5; pp. 1277 - 1286
• Main Authors: Cohen, Charlotte, Tessier, Williams, Gronnier, Caroline, Renaud, Florence, Pasquer, Arnaud, Théreaux, Jérémie, Gagnière, Johan, Meunier, Bernard, Collet, Denis, Piessen, Guillaume, Mariette, Christophe
• Format: Journal Article
• Language: English
• Published: Cham Springer International Publishing 01.05.2018; Springer Nature B.V; Springer Verlag
• Subjects: Adult; Aged; Aged, 80 and over; Anastomosis; Anastomotic Leak - etiology; Cancer; Carcinoma, Squamous Cell - pathology; Carcinoma, Squamous Cell - therapy; Cervix; Chemoradiotherapy; Data processing; Esophageal cancer; Esophageal Neoplasms - pathology; Esophageal Neoplasms - therapy; Esophagectomy - adverse effects; Esophagus; Female; Health risk assessment; Hospital Mortality; Human health and pathology; Humans; Life Sciences; Male; Medical prognosis; Medicine; Medicine & Public Health; Middle Aged; Morbidity; Mortality; Neoplasm Recurrence, Local - surgery; Neoplasm Staging; Neoplasm, Residual; Oncology; Radiotherapy Dosage; Retrospective Studies; Salvage Therapy - adverse effects; Surgery; Surgical Oncology; Survival Rate; Thoracic Oncology; Treatment Outcome; Esophageal Cancer; Anastomosis Location; Cervical Anastomosis; ypTNM Stage; Definitive Chemoradiotherapy

Background Locoregional recurrence rates after definitive chemoradiotherapy (dCRT) for locally advanced esophageal cancer (EC) are high. Salvage surgery (SALV) is considered the best treatment option in case of persistent or recurrent disease for operable patients, but SALV has been associated with...