Estrogen-induced circRNA, circPGR, functions as a ceRNA to promote estrogen receptor-positive breast cancer cell growth by regulating cell cycle-related genes

• Published in: Theranostics Vol. 11; no. 4; pp. 1732 - 1752
• Main Authors: Wang, Lei, Yi, Jia, Lu, Ling-yun, Zhang, Yue-ying, Wang, Lan, Hu, Guo-sheng, Liu, Yi-chen, Ding, Jian-cheng, Shen, Hai-feng, Zhao, Fang-qing, Huang, Hai-hua, Liu, Wen
• Format: Journal Article
• Language: English
• Published: Australia Ivyspring International Publisher Pty Ltd 2021; Ivyspring International Publisher
• Subjects: Atherosclerosis; Binding sites; Biomarkers; Breast cancer; Cell cycle; Cell growth; Estrogens; Gene expression; Leukemia; Metastasis; MicroRNAs; Proteins; Research Paper; RNA polymerase; ER-positive breast cancer; miRNA; circRNA; cell cycle; estrogen and estrogen receptor

Estrogen and estrogen receptor (ER)-regulated gene transcriptional events have been well known to be involved in ER-positive breast carcinogenesis. Meanwhile, circular RNAs (circRNAs) are emerging as a new family of functional non-coding RNAs (ncRNAs) with implications in a variety of pathological p...