Rare RNF213 variants is related to early-onset intracranial atherosclerosis: A Chinese community-based study

• Published in: Journal of stroke and cerebrovascular diseases Vol. 33; no. 11; p. 107982
• Main Authors: Fang, Jianxun, Yang, Xinzhuang, Tang, Mingyu, Li, Shengde, Han, Fei, Zhou, Lixin, Li, Mingli, Yang, Meng, Cui, Liying, Zhang, Shuyang, Zhu, Yicheng, Yao, Ming, Ni, Jun
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.11.2024
• Subjects: Extracranial atherosclerosis; Intracranial atherosclerosis; Rare variant; RNF213; Rare variant; Intracranial atherosclerosis; RNF213; Extracranial atherosclerosis

The relationship between rare variants in Ring finger protein 213 (RNF213) and intracranial atherosclerosis (ICAS) remained unelucidated. Using whole-exome sequencing (WES) and high-resolution magnetic resonance imaging (HR-MRI), this study aimed at investigating the association between rare RNF213...