Characteristics of in peripheral blood of 70 hospitalized patients and 8 diarrhea patients with COVID-19

• Published in: International journal of medical sciences Vol. 17; no. 9; pp. 1142 - 1146
• Main Authors: Wei, Xiao-Yu, Jing, Ding, Jia, Bei, Li, Qing, Zhou, Xia-Qia, Gong, Ming-Feng, Zou, Jing-Bo, Zhang, Qiang, Huang, Wen-Xiang, Tian, Wen-Guang
• Format: Journal Article
• Language: English
• Published: Australia Ivyspring International Publisher Pty Ltd 01.01.2020; Ivyspring International Publisher
• Subjects: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Betacoronavirus - isolation & purification; Biomarkers - blood; Blood tests; Child; Coronavirus Infections - blood; Coronavirus Infections - complications; Coronavirus Infections - diagnosis; Coronavirus Infections - virology; Coronaviruses; COVID-19; Creatinine; Diarrhea; Diarrhea - blood; Diarrhea - diagnosis; Diarrhea - virology; Disease transmission; Female; gamma-Glutamyltransferase - blood; Gender; Hemoglobin; Hospitals; Humans; Infections; Lungs; Lymphocytes; Male; Middle Aged; Pandemics; Patients; Pneumonia; Pneumonia, Viral - blood; Pneumonia, Viral - complications; Pneumonia, Viral - diagnosis; Pneumonia, Viral - virology; Research Paper; SARS-CoV-2; Young Adult; China; COVID-19; Diarrhea; GGT; Peripheral blood
• DOI: 10.7150/ijms.45743
• ISSN: 1449-1907

To analyze the blood test indicators of patients after infection of COVID-19 in Chongqing and analyze the clinical indicators of 8 patients with diarrhea. : From January 26, 2019 to February 13, 2020, 70 patients diagnosed with 2019-nCoV according to the World Health Organization interim guidance for NCP and divided into diarrhea and non-diarrhea groups. The laboratory tests liver and kidney function, blood routine, coagulation function, and immune status. : The study population included 70 hospitalized patients with confirmed CONV-2019. NCP patients (43males and 27 females) with a mean age of 48.57±17.80 (9~82) years and only 4.3% of patients have lung-related diseases. The positive rate of ESR, CRP, PT, IL6, lymphocyte count, GGT, Prealbumin and CD4 was more than 50%. We further analyzed the differences between 8 diarrhea patients and 62 non-diarrhea patients. Among these indicators, only Lymphocyte, CRP, Prealbumin and Cystatin C positive rate is more than 50%. Although there is no statistical difference in GGT, 100% of the 7 patients tested decreased. Our data recommended that the ESR, CRP, PT, IL6, lymphocyte count, GGT, prealbumin and CD4 have important value in the diagnosis of COVID-19, and the decrease of GGT may be an important indicator for judging the intestinal dysfunction of patients.